Dog /
2026 FDA CVM data 4,645 reports on file official source

Hound (unspecified) — FDA Adverse Event Profile

Adverse-event records and label data for Hound (unspecified) (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

Verify with FDA CVM →
Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 469 351.75 234.5 117.25 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Hound (unspecified) drawn from FDA CVM filings.

Hound (unspecified) (Dog) has 4,645 FDA adverse event reports on record, with 107 deaths reported (230.0% death rate) — ranking #41 by report volume. The most frequently reported reaction is Lack of efficacy (endoparasite) - heartworm (860 cases). The top associated drug is Ivermectin + Pyrantel As Pamoate Salt. Average age at report: 4.1 years.

Total Reports

4,645

FDA CVM filings

Deaths Reported

107

of 4,645 reports

Death Rate

230.0%

death-coded share

Avg Age at Report

4.1 yr

24.9 kg avg weight

Death-Coded Outcome Share

Hound (unspecified) death-coded reports 100.0%
Database median

230.0% of 4,645 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 24.9 kg (54.9 lbs)

Top Reported Reactions

Lack of efficacy (endoparasite) - heartworm 860
Vomiting 640
Lack of efficacy (endoparasite) - hookworm 552
INEFFECTIVE, HOOKS 269
INEFFECTIVE, HEARTWORM LARVAE 260
Lethargy (see also Central nervous system depression in 'Neurological') 253
Emesis 250
Lack of efficacy - NOS 247
Digestive tract disorder NOS 237
Diarrhoea 219
Seizure NOS 147
Other abnormal test result NOS 114
Lack of efficacy (endoparasite) - roundworm NOS 114
Lack of efficacy (ectoparasite) - flea 107
Lack of efficacy (ectoparasite) - tick NOS 106

Most Referenced Drugs

Ivermectin + Pyrantel As Pamoate Salt 1,094
Milbemycin Oxime + Spinosad 726
Pyrantel Pamoate;Sarolaner 464
Milbemycin Oxime + Praziquantel 434
Moxidectin 369
Afoxolaner 315
Melarsomine Dihydrochloride 192
Sarolaner 138
Oclacitinib Maleate 135
Spinosad 114
Ivermectin 102
Bedinvetmab 96
Carprofen 77
Milbemycin Oxime, Lufenuron 68
Lufenuron + Milbemycin Oxime 67

Outcome Breakdown

Outcome Unknown
1,876 (40.4%)
Ongoing
1,347 (29.0%)
Recovered/Normal
1,045 (22.5%)
Recovered with Sequela
273 (5.9%)
Died
55 (1.2%)
Euthanized
52 (1.1%)

Gender Distribution

Male 2,326 (50.1%)
Female 2,265 (48.8%)
Unknown 40 (0.9%)
Mixed 14 (0.3%)

Reports by Year

Year Reports Trend
2010 4
2011 60
2012 153
2013 177
2014 217
2015 252
2016 305
2017 364
2018 394
2019 469
2020 468
2021 450
2022 339
2023 358
2024 402
2025 233
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Hound (unspecified) sits in the registered size-class taxonomy. Average reported weight: 24.9 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Hound (unspecified) Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Hound (unspecified) accounts for 4,645 submitted reports and currently ranks #41 by report volume within the dog population. Of those reports, 107 involved a death outcome — a 230.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 4.1 years, with an average recorded body weight of 24.9 kg (54.9 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Hound (unspecified) are Lack of efficacy (endoparasite) - heartworm (860 reports), Vomiting (640 reports), Lack of efficacy (endoparasite) - hookworm (552 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Ivermectin + Pyrantel As Pamoate Salt appears in 1,094 reports and is the single most-referenced drug, followed by Milbemycin Oxime + Spinosad (726) and Pyrantel Pamoate;Sarolaner (464). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 4,648 reports with a recorded status is dominated by Outcome Unknown (40.4% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Hound (unspecified) Adverse Event Data

Hound (unspecified) has a moderate volume of adverse event reports (4,645). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 230.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Ivermectin + Pyrantel As Pamoate Salt, appearing in 1,094 reports. This may indicate widespread use of the medication rather than a specific safety concern for Hound (unspecified).

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Hound (unspecified)?
There are 4,645 adverse event reports involving Hound (unspecified) in the FDA database, with 107 reports involving death (230.0% death rate). Hound (unspecified) ranks #41 by report volume.
What are the most common adverse reactions reported for Hound (unspecified)?
The most commonly reported adverse reactions for Hound (unspecified) are Lack of efficacy (endoparasite) - heartworm (860 reports), Vomiting (640 reports), Lack of efficacy (endoparasite) - hookworm (552 reports), INEFFECTIVE, HOOKS (269 reports), INEFFECTIVE, HEARTWORM LARVAE (260 reports).
What drugs are most frequently associated with Hound (unspecified) adverse events?
The drugs most frequently referenced in Hound (unspecified) adverse event reports are Ivermectin + Pyrantel As Pamoate Salt (1,094 reports), Milbemycin Oxime + Spinosad (726 reports), Pyrantel Pamoate;Sarolaner (464 reports), Milbemycin Oxime + Praziquantel (434 reports), Moxidectin (369 reports).
What is the average age of Hound (unspecified) in adverse event reports?
The average age of Hound (unspecified) at the time of adverse event reports is 4.1 years, with an average weight of 24.9 kg (54.9 lbs).
Does a high number of adverse event reports mean Hound (unspecified) is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Hound (unspecified) safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Hound (unspecified) ranks #41 by total report volume. Death rate (230.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial