Total Reports
1,258
FDA CVM filings
Dog /
FDA CVM · 2025 release 1,258 reports on file
Shar Pei - FDA Adverse Event Profile
Adverse-event records for Shar Pei (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Shar Pei is #97 by FDA report volume; 7.6% of its 1,258 reports (95) were death-coded.
- #97
- most-reported dog breed
- 7.6%
- death-coded report share
- 219
- Vomiting - top reaction
- 5.5 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
95
of 1,258 reports
Death Rate
7.6%
death-coded share
Avg Age at Report
5.5 yr
23.3 kg avg weight
Death-Coded Outcome Share
Shar Pei death-coded reports 7.6%
Cross-breed median
7.6% of 1,258 shar pei reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 23.3 kg (51.4 lbs)
Top Reported Reactions
Vomiting 219
Lethargy (see also Central nervous system depression in 'Neurological') 122
Emesis 90
Diarrhoea 87
Lack of efficacy - NOS 73
Lack of efficacy (endoparasite) - heartworm 73
Anorexia 61
Lack of efficacy (ectoparasite) - flea 61
INEFFECTIVE, HEARTWORM LARVAE 56
Seizure NOS 53
Death 47
Death by euthanasia 45
Other abnormal test result NOS 44
Not eating 35
Behavioural disorder NOS 32
Most Referenced Drugs
Milbemycin Oxime + Spinosad 218
Oclacitinib Maleate 126
Ivermectin + Pyrantel As Pamoate Salt 97
Afoxolaner 83
Spinosad 81
Moxidectin 65
Pyrantel Pamoate;Sarolaner 48
Carprofen 42
Milbemycin Oxime + Praziquantel 38
Bedinvetmab 34
Fluralaner Chew Tablets 31
Maropitant Citrate 24
Ivermectin 23
Gabapentin 23
Trilostane 22
Outcome Breakdown
Outcome Unknown
390 (33.0%)
Recovered/Normal
336 (28.4%)
Ongoing
316 (26.7%)
Died
57 (4.8%)
Recovered with Sequela
45 (3.8%)
Euthanized
38 (3.2%)
Gender Distribution
Female 616 (49.0%)
Male 612 (48.6%)
Unknown 27 (2.1%)
Mixed 3 (0.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 40 | |
| 2011 | 62 | |
| 2012 | 93 | |
| 2013 | 102 | |
| 2014 | 99 | |
| 2015 | 79 | |
| 2016 | 119 | |
| 2017 | 100 | |
| 2018 | 83 | |
| 2019 | 87 | |
| 2020 | 77 | |
| 2021 | 59 | |
| 2022 | 64 | |
| 2023 | 62 | |
| 2024 | 86 | |
| 2025 | 46 | |
Shar Pei Pet Health Insights
Shar Pei accounts for 1,258 FDA adverse event reports, ranking #97 by volume among dog breeds, with 95 reports (7.6%) coded as a death outcome. Mean age at report: 5.5 years, average weight 23.3 kg (51.4 lbs).
Top reported signs: Vomiting (219), Lethargy (see also Central nervous system depression in 'Neurological') (122), Emesis (90). Most-referenced drug: Milbemycin Oxime + Spinosad (218 reports), followed by Oclacitinib Maleate (126) and Ivermectin + Pyrantel As Pamoate Salt (97).
Outcome coding on 1,182 status-recorded reports is dominated by Outcome Unknown (33.0%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Newfoundland
1,261 reports · 7.2% death rate
Saint Bernard Dog
1,253 reports · 7.8% death rate
Shepherd Dog (unspecified)
1,271 reports · 3.2% death rate
Spaniel - Cocker English
1,243 reports · 2.5% death rate
Ridgeback - Rhodesian
1,291 reports · 5.2% death rate
Coonhound (unspecified)
1,210 reports · 3.0% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Shar Pei? ▼
There are 1,258 adverse event reports involving Shar Pei in the FDA database, with 95 reports involving death (7.6% death rate). Shar Pei ranks #97 by report volume.
What are the most common adverse reactions reported for Shar Pei? ▼
The most commonly reported adverse reactions for Shar Pei are Vomiting (219 reports), Lethargy (see also Central nervous system depression in 'Neurological') (122 reports), Emesis (90 reports), Diarrhoea (87 reports), Lack of efficacy - NOS (73 reports).
What drugs are most frequently associated with Shar Pei adverse events? ▼
The drugs most frequently referenced in Shar Pei adverse event reports are Milbemycin Oxime + Spinosad (218 reports), Oclacitinib Maleate (126 reports), Ivermectin + Pyrantel As Pamoate Salt (97 reports), Afoxolaner (83 reports), Spinosad (81 reports).
What is the average age of Shar Pei in adverse event reports? ▼
The average age of Shar Pei at the time of adverse event reports is 5.5 years, with an average weight of 23.3 kg (51.4 lbs).
Does a high number of adverse event reports mean Shar Pei is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Shar Pei safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.