Total Reports
6,966
FDA CVM filings
Dog /
FDA CVM · 2025 release 6,966 reports on file
Bichon Frise - FDA Adverse Event Profile
Adverse-event records for Bichon Frise (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 6,966 reports on file, Bichon Frise sits at #32 among dog breeds by volume; death-coded share is 3.8% (267 reports).
- #32
- most-reported dog breed
- 3.8%
- death-coded report share
- 1,793
- Vomiting - top reaction
- 7.1 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
267
of 6,966 reports
Death Rate
3.8%
death-coded share
Avg Age at Report
7.1 yr
7.3 kg avg weight
Death-Coded Outcome Share
Bichon Frise death-coded reports 3.8%
Cross-breed median
3.8% of 6,966 bichon frise reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 7.3 kg (16.1 lbs)
Top Reported Reactions
Vomiting 1,793
Emesis 867
Lethargy (see also Central nervous system depression in 'Neurological') 785
Diarrhoea 617
Lack of efficacy (ectoparasite) - flea 452
Lack of efficacy - NOS 330
Anorexia 299
Lack of efficacy (endoparasite) - hookworm 262
Seizure NOS 202
Pruritus 199
Digestive tract disorder NOS 197
Behavioural disorder NOS 183
Other abnormal test result NOS 182
Emesis (multiple) 175
Decreased appetite 166
Most Referenced Drugs
Milbemycin Oxime + Spinosad 1,356
Spinosad 586
Ivermectin + Pyrantel As Pamoate Salt 493
Afoxolaner 477
Oclacitinib Maleate 418
Trilostane 370
Fluralaner Chew Tablets 299
Pyrantel Pamoate;Sarolaner 279
Moxidectin 211
Fluralaner 13.64% 12-Week Chew 171
Carprofen 167
Selamectin 152
Sarolaner 151
Milbemycin Oxime + Praziquantel 147
Maropitant Citrate 134
Outcome Breakdown
Recovered/Normal
2,688 (42.2%)
Outcome Unknown
1,821 (28.6%)
Ongoing
1,416 (22.3%)
Recovered with Sequela
172 (2.7%)
Euthanized
150 (2.4%)
Died
117 (1.8%)
Gender Distribution
Male 3,608 (51.8%)
Female 3,225 (46.3%)
Unknown 124 (1.8%)
Mixed 9 (0.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 303 | |
| 2011 | 439 | |
| 2012 | 631 | |
| 2013 | 624 | |
| 2014 | 670 | |
| 2015 | 588 | |
| 2016 | 551 | |
| 2017 | 547 | |
| 2018 | 449 | |
| 2019 | 404 | |
| 2020 | 374 | |
| 2021 | 285 | |
| 2022 | 305 | |
| 2023 | 285 | |
| 2024 | 327 | |
| 2025 | 184 | |
Bichon Frise Pet Health Insights
Bichon Frise accounts for 6,966 FDA adverse event reports, ranking #32 by volume among dog breeds, with 267 reports (3.8%) coded as a death outcome. Mean age at report: 7.1 years, average weight 7.3 kg (16.1 lbs).
Top reported signs: Vomiting (1,793), Emesis (867), Lethargy (see also Central nervous system depression in 'Neurological') (785). Most-referenced drug: Milbemycin Oxime + Spinosad (1,356 reports), followed by Spinosad (586) and Ivermectin + Pyrantel As Pamoate Salt (493).
Outcome coding on 6,364 status-recorded reports is dominated by Recovered/Normal (42.2%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Bichon Frise? ▼
There are 6,966 adverse event reports involving Bichon Frise in the FDA database, with 267 reports involving death (3.8% death rate). Bichon Frise ranks #32 by report volume.
What are the most common adverse reactions reported for Bichon Frise? ▼
The most commonly reported adverse reactions for Bichon Frise are Vomiting (1,793 reports), Emesis (867 reports), Lethargy (see also Central nervous system depression in 'Neurological') (785 reports), Diarrhoea (617 reports), Lack of efficacy (ectoparasite) - flea (452 reports).
What drugs are most frequently associated with Bichon Frise adverse events? ▼
The drugs most frequently referenced in Bichon Frise adverse event reports are Milbemycin Oxime + Spinosad (1,356 reports), Spinosad (586 reports), Ivermectin + Pyrantel As Pamoate Salt (493 reports), Afoxolaner (477 reports), Oclacitinib Maleate (418 reports).
What is the average age of Bichon Frise in adverse event reports? ▼
The average age of Bichon Frise at the time of adverse event reports is 7.1 years, with an average weight of 7.3 kg (16.1 lbs).
Does a high number of adverse event reports mean Bichon Frise is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Bichon Frise safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.