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Breed profile · FDA CVM July 2026 extract

Shepherd Dog - German adverse-event record

Adverse-event filings for Shepherd Dog - German (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#6 of 510
by report volume (all breeds)
32,220
FDA CVM reports on file
4.4%
death-coded share of reports
#161 of 275
by death-coded share (≥50 reports)

How the 32,220 reports break down

By recorded gender -- every report on file for Shepherd Dog - German, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 2,487 1,865.25 1,243.5 621.75 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Shepherd Dog - German drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Shepherd Dog - German ranks #6 of 510 by total reports (32,220) and #161 of 275 by death-coded share (4.4%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#6
This breed, reports of 510
#161
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Shepherd Dog - German has 32,220 reports now versus 31,778 in that prior snapshot: 442 more (1.4%).

Report change
+442
Death-coded reports
+21
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Shepherd Dog - German changes

Total Reports

32,220

Highest-reported breed

Deaths Reported

1,406

of 32,220 reports

Death-coded share of reports

4.4%

Below-median death-coded share

Avg Age at Report

4.6 yr

33.1 kg avg weight

Breed Safety Scorecard

D (49/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate C-
4.4%

Share of reports coded as a fatality

Euthanasia rate B-
1.8%

Share of reports resulting in euthanasia

Full recovery rate F
23.3%

Share of reports coded "Recovered/Normal"

5-year trend C-
+8%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Shepherd Dog - German death-coded reports 4.4%
Cross-breed median

4.4% of 32,220 shepherd dog - german reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Shepherd Dog - German's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

4% 41st percentile Higher share than 41% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Shepherd Dog - German 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Shepherd Dog - German among report-volume vs. death-rate peers

Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.

Source: FDA openFDA Animal & Veterinary Adverse Events database 2×2 strategic matrix plotting 30 entities by Total Reports (X) and Death Rate (%) (Y), with a crosshair dividing the plot into four quadrants. High volume, high death rateLow volume, high death rateHigh volume, low death rateLow volume, low death rate 020,00040,00060,00080,000100,000 0%5%10%15% Total Reports Death Rate (%) Shepherd Dog - German vs. all breeds, report volume and death-coded share Retriever - Labrador-93675, 3.7%Crossbred Canine/dog-70591, 3.2%Domestic Shorthair-65226, 7.2%Dog (unknown)-48820, 8.8%Retriever - Golden-35980, 3.7%Shepherd Dog - German-32220, 4.4%Chihuahua-31521, 4.2%Terrier - Yorkshire-24924, 3.7%Shih Tzu-24405, 3.6%Boxer (German Boxer)-19405, 4.4%Beagle-17970, 3.6%Pit Bull-17865, 3.1%Shepherd Dog - Australian-16274, 3.7%Terrier (unspecified)-14058, 3.1%Maltese-13940, 3.2%Dachshund (unspecified)-13512, 4.6%Cat (unknown)-13248, 9.3%Terrier - Jack Russell-10423, 3.7%Collie - Border-10130, 4.3%Siberian Husky-9811, 4.5%Domestic Longhair-9615, 7%Pug-9224, 5.2%Spitz - German Pomeranian-9086, 4.9%Terrier - Bull - American Pit-8769, 4.7%Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)-7871, 3.6%Terrier - Boston-7737, 4.5%Spaniel - Cocker American-7640, 4%Domestic (unspecified)-7576, 13.4%Poodle (unspecified)-7534, 3.4%Schnauzer - Miniature-7513, 4.4%
Source: FDA openFDA Animal & Veterinary Adverse Events database
Average weight at time of report: 33.1 kg (73.0 lbs)

Top Reported Reactions

Vomiting 4,601
Lack of efficacy (endoparasite) - heartworm 4,586
INEFFECTIVE, HEARTWORM LARVAE 3,122
Diarrhoea 2,387
Emesis 1,929
Lack of efficacy - NOS 1,890
Lethargy (see also Central nervous system depression in 'Neurological') 1,860
Lack of efficacy (endoparasite) - hookworm 1,623
Lack of efficacy (ectoparasite) - flea 1,447
Digestive tract disorder NOS 881
Seizure NOS 872
Anorexia 840
Cardiac disorder NOS 826
Lack of efficacy (ectoparasite) - tick NOS 779
Lack of efficacy (bacteria) - Borrelia 698

Most Referenced Drugs

Milbemycin Oxime + Spinosad 5,515
Ivermectin + Pyrantel As Pamoate Salt 5,017
Pyrantel Pamoate;Sarolaner 2,204
Afoxolaner 2,049
Milbemycin Oxime + Praziquantel 1,945
Moxidectin 1,744
Spinosad 1,270
Oclacitinib Maleate 1,172
Fluralaner Chew Tablets 1,151
Bedinvetmab 1,106
Fluralaner 13.64% 12-Week Chew 975
Carprofen 956
Melarsomine Dihydrochloride 590
Sarolaner 559
Ivermectin, Pyrantel 515

Outcome Breakdown

Outcome Unknown
10,748 (35.4%)
Ongoing
8,841 (29.1%)
Recovered/Normal
7,501 (24.7%)
Recovered with Sequela
1,898 (6.2%)
Died
821 (2.7%)
Euthanized
585 (1.9%)

Gender Distribution

Male 15,994 (49.6%)
Female 15,500 (48.1%)
Unknown 631 (2.0%)
Mixed 95 (0.3%)

Reports by Year

Year Reports Trend
2010 1,011
2011 1,264
2012 1,714
2013 1,633
2014 1,875
2015 2,083
2016 2,278
2017 2,388
2018 2,289
2019 2,277
2020 2,183
2021 2,071
2022 1,981
2023 2,130
2024 2,487
2025 2,236
2026 320

Shepherd Dog - German: high-volume FDA adverse-event cohort

Signature read: 32,220 reports place Shepherd Dog - German in the upper third of breed filing volume (#6 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Shepherd Dog - German sits at #6 of 510 by report volume among all breeds and #5 of 298 among dog breeds, with 32,220 reports and 1,406 (4.4%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #161 of 275. Mean age at report: 4.6 years, average weight 33.1 kg (73.0 lbs).

Top reported signs: Vomiting (4,601), Lack of efficacy (endoparasite) - heartworm (4,586), INEFFECTIVE, HEARTWORM LARVAE (3,122). Most-referenced drug: Milbemycin Oxime + Spinosad (5,515 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (5,017) and Pyrantel Pamoate;Sarolaner (2,204).

Outcome coding on 30,394 status-recorded reports is dominated by Outcome Unknown (35.4%). Annual submissions ranged 320-2,026 across 17 years on file.

Shepherd Dog - German Reporting Concentration Profile

Shepherd Dog - German is a high-volume FDA CVM cohort (32,220 reports) - enough filings to measure how concentrated the reaction and drug mix is, not just the headline totals. Across 20 named reaction terms in the stored top list, the leading three (Vomiting, Lack of efficacy (endoparasite) - heartworm, INEFFECTIVE, HEARTWORM LARVAE) account for 38.9% of listed reaction mentions. The Herfindahl index on that list is 0.079 (1.0 = a single reaction owns every mention; lower = a broader clinical mix).

On the drug side, 20 referenced products appear in the top list; the leading three (Milbemycin Oxime + Spinosad, Ivermectin + Pyrantel As Pamoate Salt, Pyrantel Pamoate;Sarolaner) cover 43.8% of those mentions. That multi-product footprint is the profile thin-report breeds cannot show - their pages stop at a short bar list because the sample cannot support a concentration read.

Outcome coding on 30,394 status-recorded filings splits roughly 4.6% severe (died or euthanized - 1,406 reports) versus 30.9% recovered or recovered-with-sequela (9,399). Read that split next to the 4.4% death-coded share above - both track reporting severity bias in a popular breed, not a proven mortality rate.

Peak filing year was 2024 (2,487 reports); the lightest year on file was 2026 (320). From 2024 to 2025, annual volume fell 10.1% (2,487 → 2,236). Year-to-year swings at this volume usually track product launches, owner awareness, and reporting campaigns more than sudden breed-health shocks.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Chihuahua
31,521 reports · 4.2% death-coded
Retriever - Golden
35,980 reports · 3.7% death-coded
Terrier - Yorkshire
24,924 reports · 3.7% death-coded
Shih Tzu
24,405 reports · 3.6% death-coded
Boxer (German Boxer)
19,405 reports · 4.4% death-coded
Beagle
17,970 reports · 3.6% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Shepherd Dog - German drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (4.4% death-coded here).

Siberian 4.2% · Cat Bengal 4.6% · Cat Scottish Fold Longhair 4.8% · Cat British cat 3.8% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (33.1 kg here).

Nubian 32.8 kg · Goat Fish (other) 32.4 kg · Fish Katahdin 32.4 kg · Sheep Goat (unknown) 35.9 kg · Goat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Shepherd Dog - German? ▼
There are 32,220 adverse event reports involving Shepherd Dog - German in the FDA database, of which 1,406 were death-coded (4.4% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Shepherd Dog - German ranks #6 of 510 by report volume among all breeds PlainBreed indexes (#5 of 298 among dog breeds).
Where does Shepherd Dog - German sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Shepherd Dog - German is #6 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #5 of 298. Among breeds with at least 50 reports, its death-coded share ranks #161 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Shepherd Dog - German? ▼
The most commonly reported adverse reactions for Shepherd Dog - German are Vomiting (4,601 reports), Lack of efficacy (endoparasite) - heartworm (4,586 reports), INEFFECTIVE, HEARTWORM LARVAE (3,122 reports), Diarrhoea (2,387 reports), Emesis (1,929 reports).
What drugs are most frequently associated with Shepherd Dog - German adverse events? ▼
The drugs most frequently referenced in Shepherd Dog - German adverse event reports are Milbemycin Oxime + Spinosad (5,515 reports), Ivermectin + Pyrantel As Pamoate Salt (5,017 reports), Pyrantel Pamoate;Sarolaner (2,204 reports), Afoxolaner (2,049 reports), Milbemycin Oxime + Praziquantel (1,945 reports).
What is the average age of Shepherd Dog - German in adverse event reports? ▼
The average age of Shepherd Dog - German at the time of adverse event reports is 4.6 years, with an average weight of 33.1 kg (73.0 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Shepherd Dog - German (Dog), extract as of July 2026 extract. 32,220 reports · 1,406 death-coded (4.4% of reports, not a mortality rate) · #6 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →