Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
4,619
Total Reports
448
Deaths Reported
970.0%
Death Rate
7.5 yr
Avg Age at Report
Average weight at time of report: 4.6 kg (10.1 lbs)
Top Reported Reactions
Lack of efficacy (ectoparasite) - flea 561
Application site hair loss 378
Vomiting 373
Lethargy (see also Central nervous system depression in 'Neurological') 304
Death 297
Lack of efficacy - NOS 236
Application site alopecia 200
Anorexia 199
Behavioural disorder NOS 173
Diarrhoea 163
Seizure NOS 126
Death by euthanasia 126
Decreased appetite 124
Not eating 121
Lethargy (see also Central nervous system depression in Neurological) 115
Most Referenced Drugs
Selamectin;Sarolaner 1,299
Selamectin 1,097
Frunevetmab 802
Cefovecin 419
Maropitant Citrate 200
Buprenorphine 180
Dexmedetomidine Hydrochloride 129
Butorphanol 69
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 66
Methylprednisolone Acetate 65
Ketamine 64
Isoflurane 63
Fluralaner Spot-On Solution 58
Oclacitinib Maleate 52
Sarolaner 49
Outcome Breakdown
Outcome Unknown
2,633 (56.7%)
Ongoing
978 (21.1%)
Recovered/Normal
580 (12.5%)
Died
316 (6.8%)
Euthanized
135 (2.9%)
Recovered with Sequela
4 (0.1%)
Gender Distribution
Unknown 2,238 (48.5%)
Male 1,194 (25.8%)
Female 1,053 (22.8%)
Mixed 134 (2.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 3 | |
| 2013 | 3 | |
| 2014 | 10 | |
| 2015 | 115 | |
| 2016 | 319 | |
| 2017 | 287 | |
| 2018 | 321 | |
| 2019 | 456 | |
| 2020 | 467 | |
| 2021 | 445 | |
| 2022 | 452 | |
| 2023 | 724 | |
| 2024 | 704 | |
| 2025 | 313 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #42 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.