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Breed profile · FDA CVM July 2026 extract

Bulldog - American adverse-event record

Adverse-event filings for Bulldog - American (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#73 of 510
by report volume (all breeds)
2,514
FDA CVM reports on file
5.1%
death-coded share of reports
#129 of 275
by death-coded share (≥50 reports)

How the 2,514 reports break down

By recorded gender -- every report on file for Bulldog - American, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 207 155.25 103.5 51.75 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Bulldog - American drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Bulldog - American ranks #73 of 510 by total reports (2,514) and #129 of 275 by death-coded share (5.1%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#73
This breed, reports of 510
#129
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bulldog - American has 2,514 reports now versus 2,466 in that prior snapshot: 48 more (1.9%).

Report change
+48
Death-coded reports
+3
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bulldog - American changes

Total Reports

2,514

High report volume

Deaths Reported

127

of 2,514 reports

Death-coded share of reports

5.1%

Above-median death-coded share

Avg Age at Report

4.3 yr

31.6 kg avg weight

Breed Safety Scorecard

C- (50/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate D
5.1%

Share of reports coded as a fatality

Euthanasia rate D
2.3%

Share of reports resulting in euthanasia

Full recovery rate C
30.9%

Share of reports coded "Recovered/Normal"

5-year trend D
+8%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Bulldog - American death-coded reports 5.1%
Cross-breed median

5.1% of 2,514 bulldog - american reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Bulldog - American's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

5% 53rd percentile Higher share than 53% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Bulldog - American 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 31.6 kg (69.7 lbs)

Top Reported Reactions

Vomiting 532
Lack of efficacy (endoparasite) - heartworm 217
Emesis 215
Lethargy (see also Central nervous system depression in 'Neurological') 195
Diarrhoea 186
Lack of efficacy (ectoparasite) - flea 164
Lack of efficacy - NOS 138
INEFFECTIVE, HEARTWORM LARVAE 106
Hives (see also 'Skin') 103
Lack of efficacy (endoparasite) - hookworm 86
Seizure NOS 80
Anorexia 61
Death by euthanasia 61
Death 59
Emesis (multiple) 59

Most Referenced Drugs

Milbemycin Oxime + Spinosad 596
Moxidectin 231
Oclacitinib Maleate 205
Pyrantel Pamoate;Sarolaner 187
Spinosad 145
Milbemycin Oxime + Praziquantel 136
Fluralaner 13.64% 12-Week Chew 116
Fluralaner Chew Tablets 115
Carprofen 99
Bedinvetmab 82
Ivermectin + Pyrantel As Pamoate Salt 73
Sarolaner 57
Trilostane 50
Anti-Il31 Mab Mcs Lot #1283563 49
Maropitant Citrate 48

Outcome Breakdown

Ongoing
814 (33.8%)
Recovered/Normal
777 (32.2%)
Outcome Unknown
635 (26.3%)
Died
70 (2.9%)
Recovered with Sequela
57 (2.4%)
Euthanized
57 (2.4%)

Gender Distribution

Male 1,432 (57.0%)
Female 1,031 (41.0%)
Unknown 42 (1.7%)
Mixed 9 (0.4%)

Reports by Year

Year Reports Trend
2010 54
2011 60
2012 99
2013 131
2014 147
2015 181
2016 160
2017 196
2018 190
2019 176
2020 207
2021 169
2022 173
2023 157
2024 197
2025 183
2026 34

Bulldog - American: high-volume FDA adverse-event cohort

Signature read: 2,514 reports place Bulldog - American in the upper third of breed filing volume (#73 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Bulldog - American sits at #73 of 510 by report volume among all breeds and #62 of 298 among dog breeds, with 2,514 reports and 127 (5.1%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #129 of 275. Mean age at report: 4.3 years, average weight 31.6 kg (69.7 lbs).

Top reported signs: Vomiting (532), Lack of efficacy (endoparasite) - heartworm (217), Emesis (215). Most-referenced drug: Milbemycin Oxime + Spinosad (596 reports), followed by Moxidectin (231) and Oclacitinib Maleate (205).

Outcome coding on 2,410 status-recorded reports is dominated by Ongoing (33.8%). Annual submissions ranged 34-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Weimaraner
2,538 reports · 4.5% death-coded
Pekingese
2,552 reports · 4.0% death-coded
Catahoula Leopard Dog
2,402 reports · 2.2% death-coded
Terrier - Bull - Staffordshire
2,752 reports · 4.4% death-coded
Spaniel - Springer English
2,268 reports · 4.0% death-coded
Corgi (unspecified)
2,865 reports · 4.2% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Bulldog - American drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (5.1% death-coded here).

Egyptian Mau 5.3% · Cat Scottish Fold Longhair 4.8% · Cat Bengal 4.6% · Cat Norwegian Forest 5.7% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (31.6 kg here).

Fish (other) 32.4 kg · Fish Katahdin 32.4 kg · Sheep Nubian 32.8 kg · Goat Goat (unknown) 35.9 kg · Goat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Bulldog - American? ▼
There are 2,514 adverse event reports involving Bulldog - American in the FDA database, of which 127 were death-coded (5.1% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Bulldog - American ranks #73 of 510 by report volume among all breeds PlainBreed indexes (#62 of 298 among dog breeds).
Where does Bulldog - American sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Bulldog - American is #73 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #62 of 298. Among breeds with at least 50 reports, its death-coded share ranks #129 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Bulldog - American? ▼
The most commonly reported adverse reactions for Bulldog - American are Vomiting (532 reports), Lack of efficacy (endoparasite) - heartworm (217 reports), Emesis (215 reports), Lethargy (see also Central nervous system depression in 'Neurological') (195 reports), Diarrhoea (186 reports).
What drugs are most frequently associated with Bulldog - American adverse events? ▼
The drugs most frequently referenced in Bulldog - American adverse event reports are Milbemycin Oxime + Spinosad (596 reports), Moxidectin (231 reports), Oclacitinib Maleate (205 reports), Pyrantel Pamoate;Sarolaner (187 reports), Spinosad (145 reports).
What is the average age of Bulldog - American in adverse event reports? ▼
The average age of Bulldog - American at the time of adverse event reports is 4.3 years, with an average weight of 31.6 kg (69.7 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bulldog - American (Dog), extract as of July 2026 extract. 2,514 reports · 127 death-coded (5.1% of reports, not a mortality rate) · #73 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →