Total Reports
2,409
FDA CVM filings
Dog /
FDA CVM · 2025 release 2,409 reports on file
Bulldog - American - FDA Adverse Event Profile
Adverse-event records for Bulldog - American (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Bulldog - American is #73 by FDA report volume; 4.9% of its 2,409 reports (119) were death-coded.
- #73
- most-reported dog breed
- 4.9%
- death-coded report share
- 516
- Vomiting - top reaction
- 4.3 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
119
of 2,409 reports
Death Rate
4.9%
death-coded share
Avg Age at Report
4.3 yr
31.7 kg avg weight
Death-Coded Outcome Share
Bulldog - American death-coded reports 4.9%
Cross-breed median
4.9% of 2,409 bulldog - american reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 31.7 kg (69.9 lbs)
Top Reported Reactions
Vomiting 516
Emesis 214
Lack of efficacy (endoparasite) - heartworm 203
Lethargy (see also Central nervous system depression in 'Neurological') 195
Diarrhoea 180
Lack of efficacy (ectoparasite) - flea 161
Lack of efficacy - NOS 131
INEFFECTIVE, HEARTWORM LARVAE 106
Hives (see also 'Skin') 103
Lack of efficacy (endoparasite) - hookworm 81
Seizure NOS 77
Anorexia 61
Death by euthanasia 58
Facial swelling (see also 'Skin') 57
Emesis (multiple) 57
Most Referenced Drugs
Milbemycin Oxime + Spinosad 595
Moxidectin 218
Oclacitinib Maleate 195
Pyrantel Pamoate;Sarolaner 168
Spinosad 145
Milbemycin Oxime + Praziquantel 133
Fluralaner Chew Tablets 115
Fluralaner 13.64% 12-Week Chew 111
Carprofen 91
Ivermectin + Pyrantel As Pamoate Salt 69
Bedinvetmab 69
Sarolaner 55
Trilostane 50
Maropitant Citrate 45
Selamectin 43
Outcome Breakdown
Recovered/Normal
761 (33.0%)
Ongoing
755 (32.8%)
Outcome Unknown
614 (26.6%)
Died
65 (2.8%)
Recovered with Sequela
56 (2.4%)
Euthanized
54 (2.3%)
Gender Distribution
Male 1,370 (56.9%)
Female 989 (41.1%)
Unknown 41 (1.7%)
Mixed 9 (0.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 54 | |
| 2011 | 60 | |
| 2012 | 99 | |
| 2013 | 131 | |
| 2014 | 147 | |
| 2015 | 181 | |
| 2016 | 160 | |
| 2017 | 196 | |
| 2018 | 190 | |
| 2019 | 176 | |
| 2020 | 207 | |
| 2021 | 169 | |
| 2022 | 172 | |
| 2023 | 157 | |
| 2024 | 192 | |
| 2025 | 118 | |
Bulldog - American Pet Health Insights
Bulldog - American accounts for 2,409 FDA adverse event reports, ranking #73 by volume among dog breeds, with 119 reports (4.9%) coded as a death outcome. Mean age at report: 4.3 years, average weight 31.7 kg (69.9 lbs).
Top reported signs: Vomiting (516), Emesis (214), Lack of efficacy (endoparasite) - heartworm (203). Most-referenced drug: Milbemycin Oxime + Spinosad (595 reports), followed by Moxidectin (218) and Oclacitinib Maleate (195).
Outcome coding on 2,305 status-recorded reports is dominated by Recovered/Normal (33.0%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Weimaraner
2,480 reports · 4.6% death rate
Catahoula Leopard Dog
2,316 reports · 2.3% death rate
Pekingese
2,525 reports · 4.0% death rate
Terrier - Bull - Staffordshire
2,607 reports · 4.4% death rate
Spaniel - Springer English
2,187 reports · 3.9% death rate
Shepherd (unspecified)
2,725 reports · 4.4% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Bulldog - American? ▼
There are 2,409 adverse event reports involving Bulldog - American in the FDA database, with 119 reports involving death (4.9% death rate). Bulldog - American ranks #73 by report volume.
What are the most common adverse reactions reported for Bulldog - American? ▼
The most commonly reported adverse reactions for Bulldog - American are Vomiting (516 reports), Emesis (214 reports), Lack of efficacy (endoparasite) - heartworm (203 reports), Lethargy (see also Central nervous system depression in 'Neurological') (195 reports), Diarrhoea (180 reports).
What drugs are most frequently associated with Bulldog - American adverse events? ▼
The drugs most frequently referenced in Bulldog - American adverse event reports are Milbemycin Oxime + Spinosad (595 reports), Moxidectin (218 reports), Oclacitinib Maleate (195 reports), Pyrantel Pamoate;Sarolaner (168 reports), Spinosad (145 reports).
What is the average age of Bulldog - American in adverse event reports? ▼
The average age of Bulldog - American at the time of adverse event reports is 4.3 years, with an average weight of 31.7 kg (69.9 lbs).
Does a high number of adverse event reports mean Bulldog - American is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Bulldog - American safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.