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2026 FDA CVM data 17,507 reports on file official source

Beagle — FDA Adverse Event Profile

Adverse-event records and label data for Beagle (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 1,314 985.5 657 328.5 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Beagle drawn from FDA CVM filings.

Beagle (Dog) has 17,507 FDA adverse event reports on record, with 635 deaths reported (360.0% death rate) — ranking #11 by report volume. The most frequently reported reaction is Vomiting (2,869 cases). The top associated drug is Ivermectin + Pyrantel As Pamoate Salt. Average age at report: 5.7 years.

Total Reports

17,507

FDA CVM filings

Deaths Reported

635

of 17,507 reports

Death Rate

360.0%

death-coded share

Avg Age at Report

5.7 yr

14.6 kg avg weight

Death-Coded Outcome Share

Beagle death-coded reports 100.0%
Database median

360.0% of 17,507 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 14.6 kg (32.2 lbs)

Top Reported Reactions

Vomiting 2,869
Lack of efficacy (endoparasite) - hookworm 1,654
Lack of efficacy (endoparasite) - heartworm 1,577
INEFFECTIVE, HEARTWORM LARVAE 1,280
Lethargy (see also Central nervous system depression in 'Neurological') 1,222
Emesis 1,161
Lack of efficacy - NOS 1,128
Digestive tract disorder NOS 1,016
Diarrhoea 1,000
Lack of efficacy (ectoparasite) - flea 644
Seizure NOS 634
INEFFECTIVE, HOOKS 589
INEFFECTIVE, ASCARIDS NOS 512
Anorexia 473
Other abnormal test result NOS 414

Most Referenced Drugs

Ivermectin + Pyrantel As Pamoate Salt 2,805
Milbemycin Oxime + Spinosad 2,591
Afoxolaner 1,033
Moxidectin 1,022
Milbemycin Oxime + Praziquantel 943
Pyrantel Pamoate;Sarolaner 933
Spinosad 737
Trilostane 681
Oclacitinib Maleate 544
Fluralaner Chew Tablets 538
Carprofen 418
Melarsomine Dihydrochloride 410
Sarolaner 387
Fluralaner 13.64% 12-Week Chew 334
Milbemycin Oxime 294

Outcome Breakdown

Outcome Unknown
6,223 (37.9%)
Recovered/Normal
4,617 (28.1%)
Ongoing
4,067 (24.8%)
Recovered with Sequela
879 (5.4%)
Euthanized
351 (2.1%)
Died
289 (1.8%)

Gender Distribution

Female 9,015 (51.5%)
Male 8,154 (46.6%)
Unknown 250 (1.4%)
Mixed 88 (0.5%)

Reports by Year

Year Reports Trend
2010 609
2011 716
2012 1,156
2013 1,119
2014 1,180
2015 1,270
2016 1,354
2017 1,399
2018 1,314
2019 1,272
2020 1,207
2021 1,107
2022 977
2023 1,108
2024 1,105
2025 614
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Beagle sits in the registered size-class taxonomy. Average reported weight: 14.6 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Beagle Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Beagle accounts for 17,507 submitted reports and currently ranks #11 by report volume within the dog population. Of those reports, 635 involved a death outcome — a 360.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 5.7 years, with an average recorded body weight of 14.6 kg (32.2 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Beagle are Vomiting (2,869 reports), Lack of efficacy (endoparasite) - hookworm (1,654 reports), Lack of efficacy (endoparasite) - heartworm (1,577 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Ivermectin + Pyrantel As Pamoate Salt appears in 2,805 reports and is the single most-referenced drug, followed by Milbemycin Oxime + Spinosad (2,591) and Afoxolaner (1,033). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 16,426 reports with a recorded status is dominated by Outcome Unknown (37.9% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Beagle Adverse Event Data

With 17,507 adverse event reports, Beagle has one of the larger report volumes in the FDA database. This typically reflects breed popularity rather than inherent health risk — more pets of a breed means more veterinary encounters and more opportunity for adverse event reporting.

The 360.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Ivermectin + Pyrantel As Pamoate Salt, appearing in 2,805 reports. This may indicate widespread use of the medication rather than a specific safety concern for Beagle.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Beagle?
There are 17,507 adverse event reports involving Beagle in the FDA database, with 635 reports involving death (360.0% death rate). Beagle ranks #11 by report volume.
What are the most common adverse reactions reported for Beagle?
The most commonly reported adverse reactions for Beagle are Vomiting (2,869 reports), Lack of efficacy (endoparasite) - hookworm (1,654 reports), Lack of efficacy (endoparasite) - heartworm (1,577 reports), INEFFECTIVE, HEARTWORM LARVAE (1,280 reports), Lethargy (see also Central nervous system depression in 'Neurological') (1,222 reports).
What drugs are most frequently associated with Beagle adverse events?
The drugs most frequently referenced in Beagle adverse event reports are Ivermectin + Pyrantel As Pamoate Salt (2,805 reports), Milbemycin Oxime + Spinosad (2,591 reports), Afoxolaner (1,033 reports), Moxidectin (1,022 reports), Milbemycin Oxime + Praziquantel (943 reports).
What is the average age of Beagle in adverse event reports?
The average age of Beagle at the time of adverse event reports is 5.7 years, with an average weight of 14.6 kg (32.2 lbs).
Does a high number of adverse event reports mean Beagle is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Beagle safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Beagle ranks #11 by total report volume. Death rate (360.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial