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Breed profile · FDA CVM July 2026 extract

Bulldog adverse-event record

Adverse-event filings for Bulldog (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

#32 of 510
by report volume (all breeds)
7,268
FDA CVM reports on file
4.7%
death-coded share of reports
#143 of 275
by death-coded share (≥50 reports)

How the 7,268 reports break down

By recorded gender -- every report on file for Bulldog, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 656 492 328 164 0 2016 2017 2018 2019 2020 2021 2022 2023 Reports filed Death-coded reports
Annual report volume for Bulldog drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Bulldog ranks #32 of 510 by total reports (7,268) and #143 of 275 by death-coded share (4.7%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#32
This breed, reports of 510
#143
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bulldog has 7,268 reports now versus 7,268 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bulldog changes

Total Reports

7,268

Highest-reported breed

Deaths Reported

345

of 7,268 reports

Death-coded share of reports

4.7%

Below-median death-coded share

Avg Age at Report

3.9 yr

25.5 kg avg weight

Breed Safety Scorecard

B (73/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate D
4.7%

Share of reports coded as a fatality

Euthanasia rate A
1.3%

Share of reports resulting in euthanasia

Full recovery rate A-
36.6%

Share of reports coded "Recovered/Normal"

5-year trend A
-39%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Bulldog death-coded reports 4.7%
Cross-breed median

4.7% of 7,268 bulldog reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Bulldog's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

5% 48th percentile Higher share than 48% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Bulldog 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Bulldog among report-volume vs. death-rate peers

Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.

Source: FDA openFDA Animal & Veterinary Adverse Events database 2×2 strategic matrix plotting 30 entities by Total Reports (X) and Death Rate (%) (Y), with a crosshair dividing the plot into four quadrants. High volume, high death rateLow volume, high death rateHigh volume, low death rateLow volume, low death rate 020,00040,00060,00080,000100,000 0%5%10%15% Total Reports Death Rate (%) Bulldog vs. all breeds, report volume and death-coded share Retriever - Labrador-93675, 3.7%Crossbred Canine/dog-70591, 3.2%Domestic Shorthair-65226, 7.2%Dog (unknown)-48820, 8.8%Retriever - Golden-35980, 3.7%Shepherd Dog - German-32220, 4.4%Chihuahua-31521, 4.2%Terrier - Yorkshire-24924, 3.7%Shih Tzu-24405, 3.6%Boxer (German Boxer)-19405, 4.4%Beagle-17970, 3.6%Pit Bull-17865, 3.1%Shepherd Dog - Australian-16274, 3.7%Terrier (unspecified)-14058, 3.1%Maltese-13940, 3.2%Dachshund (unspecified)-13512, 4.6%Cat (unknown)-13248, 9.3%Terrier - Jack Russell-10423, 3.7%Collie - Border-10130, 4.3%Siberian Husky-9811, 4.5%Domestic Longhair-9615, 7%Pug-9224, 5.2%Spitz - German Pomeranian-9086, 4.9%Terrier - Bull - American Pit-8769, 4.7%Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)-7871, 3.6%Terrier - Boston-7737, 4.5%Spaniel - Cocker American-7640, 4%Domestic (unspecified)-7576, 13.4%Poodle (unspecified)-7534, 3.4%Schnauzer - Miniature-7513, 4.4%
Source: FDA openFDA Animal & Veterinary Adverse Events database
Average weight at time of report: 25.5 kg (56.2 lbs)

Top Reported Reactions

Vomiting 1,582
Emesis 945
Lethargy (see also Central nervous system depression in 'Neurological') 732
Diarrhoea 568
Lack of efficacy - NOS 414
Lack of efficacy (ectoparasite) - flea 355
Seizure NOS 329
Lack of efficacy (endoparasite) - heartworm 290
INEFFECTIVE, HEARTWORM LARVAE 257
Death 217
Anorexia 210
Hives (see also 'Skin') 200
Emesis (multiple) 177
Lack of efficacy (endoparasite) - hookworm 175
Other abnormal test result NOS 159

Most Referenced Drugs

Milbemycin Oxime + Spinosad 1,805
Oclacitinib Maleate 617
Spinosad 545
Ivermectin + Pyrantel As Pamoate Salt 526
Afoxolaner 423
Moxidectin 410
Fluralaner Chew Tablets 401
Pyrantel Pamoate;Sarolaner 217
Carprofen 200
Milbemycin Oxime + Praziquantel 175
Cyclosporine 140
Sarolaner 134
Fluralaner 13.64% 12-Week Chew 127
Imidacloprid + Moxidectin 123
Anti-Il31 Mab Mcs Lot #1283563 123

Outcome Breakdown

Recovered/Normal
2,660 (39.5%)
Outcome Unknown
1,851 (27.5%)
Ongoing
1,616 (24.0%)
Recovered with Sequela
256 (3.8%)
Died
249 (3.7%)
Euthanized
96 (1.4%)

Gender Distribution

Male 3,923 (54.0%)
Female 3,130 (43.1%)
Unknown 189 (2.6%)
Mixed 26 (0.4%)

Reports by Year

Year Reports Trend
2010 294
2011 457
2012 651
2013 591
2014 589
2015 650
2016 656
2017 606
2018 565
2019 538
2020 499
2021 446
2022 399
2023 327

Bulldog: high-volume FDA adverse-event cohort

Signature read: 7,268 reports place Bulldog in the upper third of breed filing volume (#32 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Bulldog sits at #32 of 510 by report volume among all breeds and #28 of 298 among dog breeds, with 7,268 reports and 345 (4.7%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #143 of 275. Mean age at report: 3.9 years, average weight 25.5 kg (56.2 lbs).

Top reported signs: Vomiting (1,582), Emesis (945), Lethargy (see also Central nervous system depression in 'Neurological') (732). Most-referenced drug: Milbemycin Oxime + Spinosad (1,805 reports), followed by Oclacitinib Maleate (617) and Spinosad (545).

Outcome coding on 6,728 status-recorded reports is dominated by Recovered/Normal (39.5%). Annual submissions ranged 294-2,023 across 14 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Nationwide breeds with similar profiles

High-volume peer sets for Bulldog drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (4.7% death-coded here).

Similar average weight

Nearest other-species breeds by reported average weight (25.5 kg here).

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Bulldog?
There are 7,268 adverse event reports involving Bulldog in the FDA database, of which 345 were death-coded (4.7% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Bulldog ranks #32 of 510 by report volume among all breeds PlainBreed indexes (#28 of 298 among dog breeds).
Where does Bulldog sit among other breeds in PlainBreed's corpus?
According to FDA CVM report volume, Bulldog is #32 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #28 of 298. Among breeds with at least 50 reports, its death-coded share ranks #143 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Bulldog?
The most commonly reported adverse reactions for Bulldog are Vomiting (1,582 reports), Emesis (945 reports), Lethargy (see also Central nervous system depression in 'Neurological') (732 reports), Diarrhoea (568 reports), Lack of efficacy - NOS (414 reports).
What drugs are most frequently associated with Bulldog adverse events?
The drugs most frequently referenced in Bulldog adverse event reports are Milbemycin Oxime + Spinosad (1,805 reports), Oclacitinib Maleate (617 reports), Spinosad (545 reports), Ivermectin + Pyrantel As Pamoate Salt (526 reports), Afoxolaner (423 reports).
What is the average age of Bulldog in adverse event reports?
The average age of Bulldog at the time of adverse event reports is 3.9 years, with an average weight of 25.5 kg (56.2 lbs).

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bulldog (Dog), extract as of July 2026 extract. 7,268 reports · 345 death-coded (4.7% of reports, not a mortality rate) · #32 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →