Total Reports
7,270
FDA CVM filings
Dog /
FDA CVM · 2025 release 7,270 reports on file
Bulldog - FDA Adverse Event Profile
Adverse-event records for Bulldog (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 7,270 reports on file, Bulldog sits at #30 among dog breeds by volume; death-coded share is 4.8% (346 reports).
- #30
- most-reported dog breed
- 4.8%
- death-coded report share
- 1,582
- Vomiting - top reaction
- 3.9 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
346
of 7,270 reports
Death Rate
4.8%
death-coded share
Avg Age at Report
3.9 yr
25.5 kg avg weight
Death-Coded Outcome Share
Bulldog death-coded reports 4.8%
Cross-breed median
4.8% of 7,270 bulldog reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 25.5 kg (56.2 lbs)
Top Reported Reactions
Vomiting 1,582
Emesis 945
Lethargy (see also Central nervous system depression in 'Neurological') 732
Diarrhoea 568
Lack of efficacy - NOS 414
Lack of efficacy (ectoparasite) - flea 355
Seizure NOS 329
Lack of efficacy (endoparasite) - heartworm 290
INEFFECTIVE, HEARTWORM LARVAE 258
Death 218
Anorexia 210
Hives (see also 'Skin') 200
Emesis (multiple) 177
Lack of efficacy (endoparasite) - hookworm 175
Other abnormal test result NOS 159
Most Referenced Drugs
Milbemycin Oxime + Spinosad 1,805
Oclacitinib Maleate 617
Spinosad 545
Ivermectin + Pyrantel As Pamoate Salt 527
Afoxolaner 423
Moxidectin 411
Fluralaner Chew Tablets 401
Pyrantel Pamoate;Sarolaner 217
Carprofen 200
Milbemycin Oxime + Praziquantel 175
Cyclosporine 140
Sarolaner 134
Fluralaner 13.64% 12-Week Chew 127
Imidacloprid + Moxidectin 123
Anti-Il31 Mab Mcs Lot #1283563 123
Outcome Breakdown
Recovered/Normal
2,660 (39.5%)
Outcome Unknown
1,852 (27.5%)
Ongoing
1,616 (24.0%)
Recovered with Sequela
256 (3.8%)
Died
250 (3.7%)
Euthanized
96 (1.4%)
Gender Distribution
Male 3,923 (54.0%)
Female 3,132 (43.1%)
Unknown 189 (2.6%)
Mixed 26 (0.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 294 | |
| 2011 | 457 | |
| 2012 | 651 | |
| 2013 | 591 | |
| 2014 | 589 | |
| 2015 | 650 | |
| 2016 | 656 | |
| 2017 | 606 | |
| 2018 | 566 | |
| 2019 | 538 | |
| 2020 | 499 | |
| 2021 | 446 | |
| 2022 | 400 | |
| 2023 | 327 | |
Bulldog Pet Health Insights
Bulldog accounts for 7,270 FDA adverse event reports, ranking #30 by volume among dog breeds, with 346 reports (4.8%) coded as a death outcome. Mean age at report: 3.9 years, average weight 25.5 kg (56.2 lbs).
Top reported signs: Vomiting (1,582), Emesis (945), Lethargy (see also Central nervous system depression in 'Neurological') (732). Most-referenced drug: Milbemycin Oxime + Spinosad (1,805 reports), followed by Oclacitinib Maleate (617) and Spinosad (545).
Outcome coding on 6,730 status-recorded reports is dominated by Recovered/Normal (39.5%). Annual submissions ranged 2,010-2,023 across 14 years on file.
Dog Breeds With a Similar Report Volume
Poodle (unspecified)
7,250 reports · 3.5% death rate
Schnauzer - Miniature
7,307 reports · 4.4% death rate
Terrier - Boston
7,526 reports · 4.6% death rate
Spaniel - Cocker American
7,534 reports · 4.0% death rate
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)
7,541 reports · 3.6% death rate
Bichon Frise
6,966 reports · 3.8% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Bulldog? ▼
There are 7,270 adverse event reports involving Bulldog in the FDA database, with 346 reports involving death (4.8% death rate). Bulldog ranks #30 by report volume.
What are the most common adverse reactions reported for Bulldog? ▼
The most commonly reported adverse reactions for Bulldog are Vomiting (1,582 reports), Emesis (945 reports), Lethargy (see also Central nervous system depression in 'Neurological') (732 reports), Diarrhoea (568 reports), Lack of efficacy - NOS (414 reports).
What drugs are most frequently associated with Bulldog adverse events? ▼
The drugs most frequently referenced in Bulldog adverse event reports are Milbemycin Oxime + Spinosad (1,805 reports), Oclacitinib Maleate (617 reports), Spinosad (545 reports), Ivermectin + Pyrantel As Pamoate Salt (527 reports), Afoxolaner (423 reports).
What is the average age of Bulldog in adverse event reports? ▼
The average age of Bulldog at the time of adverse event reports is 3.9 years, with an average weight of 25.5 kg (56.2 lbs).
Does a high number of adverse event reports mean Bulldog is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Bulldog safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.