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2026 FDA CVM data 4,495 reports on file official source

Doberman Pinscher — FDA Adverse Event Profile

Adverse-event records and label data for Doberman Pinscher (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 310 232.5 155 77.5 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Doberman Pinscher drawn from FDA CVM filings.

Doberman Pinscher (Dog) has 4,495 FDA adverse event reports on record, with 256 deaths reported (570.0% death rate) — ranking #43 by report volume. The most frequently reported reaction is Vomiting (705 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 4.5 years.

Total Reports

4,495

FDA CVM filings

Deaths Reported

256

of 4,495 reports

Death Rate

570.0%

death-coded share

Avg Age at Report

4.5 yr

33.8 kg avg weight

Death-Coded Outcome Share

Doberman Pinscher death-coded reports 100.0%
Database median

570.0% of 4,495 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 33.8 kg (74.5 lbs)

Top Reported Reactions

Vomiting 705
Lack of efficacy (endoparasite) - heartworm 465
Diarrhoea 357
Emesis 346
INEFFECTIVE, HEARTWORM LARVAE 333
Lethargy (see also Central nervous system depression in 'Neurological') 320
Lack of efficacy (endoparasite) - hookworm 314
Lack of efficacy - NOS 301
Digestive tract disorder NOS 163
Anorexia 149
Death 137
Lack of efficacy (ectoparasite) - flea 129
Other abnormal test result NOS 127
Cardiac disorder NOS 112
Seizure NOS 109

Most Referenced Drugs

Milbemycin Oxime + Spinosad 846
Ivermectin + Pyrantel As Pamoate Salt 609
Afoxolaner 261
Moxidectin 249
Pyrantel Pamoate;Sarolaner 226
Milbemycin Oxime + Praziquantel 220
Spinosad 193
Carprofen 141
Fluralaner Chew Tablets 139
Oclacitinib Maleate 101
Fluralaner 13.64% 12-Week Chew 96
Bedinvetmab 92
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 84
Ivermectin, Pyrantel 80
Selamectin 75

Outcome Breakdown

Outcome Unknown
1,414 (34.1%)
Recovered/Normal
1,184 (28.5%)
Ongoing
1,082 (26.1%)
Recovered with Sequela
213 (5.1%)
Died
164 (3.9%)
Euthanized
95 (2.3%)

Gender Distribution

Female 2,214 (49.3%)
Male 2,175 (48.4%)
Unknown 89 (2.0%)
Mixed 17 (0.4%)

Reports by Year

Year Reports Trend
2010 193
2011 213
2012 300
2013 337
2014 315
2015 328
2016 344
2017 335
2018 282
2019 272
2020 276
2021 255
2022 277
2023 279
2024 310
2025 179
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Doberman Pinscher sits in the registered size-class taxonomy. Average reported weight: 33.8 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Doberman Pinscher Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Doberman Pinscher accounts for 4,495 submitted reports and currently ranks #43 by report volume within the dog population. Of those reports, 256 involved a death outcome — a 570.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 4.5 years, with an average recorded body weight of 33.8 kg (74.5 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Doberman Pinscher are Vomiting (705 reports), Lack of efficacy (endoparasite) - heartworm (465 reports), Diarrhoea (357 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 846 reports and is the single most-referenced drug, followed by Ivermectin + Pyrantel As Pamoate Salt (609) and Afoxolaner (261). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 4,152 reports with a recorded status is dominated by Outcome Unknown (34.1% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Doberman Pinscher Adverse Event Data

Doberman Pinscher has a moderate volume of adverse event reports (4,495). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 570.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 846 reports. This may indicate widespread use of the medication rather than a specific safety concern for Doberman Pinscher.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Doberman Pinscher?
There are 4,495 adverse event reports involving Doberman Pinscher in the FDA database, with 256 reports involving death (570.0% death rate). Doberman Pinscher ranks #43 by report volume.
What are the most common adverse reactions reported for Doberman Pinscher?
The most commonly reported adverse reactions for Doberman Pinscher are Vomiting (705 reports), Lack of efficacy (endoparasite) - heartworm (465 reports), Diarrhoea (357 reports), Emesis (346 reports), INEFFECTIVE, HEARTWORM LARVAE (333 reports).
What drugs are most frequently associated with Doberman Pinscher adverse events?
The drugs most frequently referenced in Doberman Pinscher adverse event reports are Milbemycin Oxime + Spinosad (846 reports), Ivermectin + Pyrantel As Pamoate Salt (609 reports), Afoxolaner (261 reports), Moxidectin (249 reports), Pyrantel Pamoate;Sarolaner (226 reports).
What is the average age of Doberman Pinscher in adverse event reports?
The average age of Doberman Pinscher at the time of adverse event reports is 4.5 years, with an average weight of 33.8 kg (74.5 lbs).
Does a high number of adverse event reports mean Doberman Pinscher is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Doberman Pinscher safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Doberman Pinscher ranks #43 by total report volume. Death rate (570.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial