Total Reports
30,657
FDA CVM filings
Dog /
FDA CVM · 2025 release 30,657 reports on file
Chihuahua - FDA Adverse Event Profile
Adverse-event records for Chihuahua (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Chihuahua's FDA record: #7 most-reported dog breed, 30,657 total reports, 4.2% death-coded (1,284 reports).
- #7
- most-reported dog breed
- 4.2%
- death-coded report share
- 6,728
- Vomiting - top reaction
- 5.8 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
1,284
of 30,657 reports
Death Rate
4.2%
death-coded share
Avg Age at Report
5.8 yr
4.8 kg avg weight
Death-Coded Outcome Share
Chihuahua death-coded reports 4.2%
Cross-breed median
4.2% of 30,657 chihuahua reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 4.8 kg (10.6 lbs)
Top Reported Reactions
Vomiting 6,728
Lack of efficacy (ectoparasite) - flea 3,703
Lethargy (see also Central nervous system depression in 'Neurological') 3,541
Emesis 2,877
Diarrhoea 2,146
Seizure NOS 1,588
Lack of efficacy - NOS 1,428
Anorexia 1,289
Lack of efficacy (endoparasite) - heartworm 1,055
Behavioural disorder NOS 946
Shaking 938
Ataxia 884
Not eating 833
Pruritus 830
Overdose 813
Most Referenced Drugs
Milbemycin Oxime + Spinosad 6,085
Spinosad 3,541
Ivermectin + Pyrantel As Pamoate Salt 1,943
Afoxolaner 1,854
Moxidectin 1,700
Pyrantel Pamoate;Sarolaner 1,400
Fluralaner Chew Tablets 1,351
Nitenpyram 1,071
Fluralaner 13.64% 12-Week Chew 910
Sarolaner 765
Milbemycin Oxime + Praziquantel 734
Trilostane 718
Oclacitinib Maleate 691
Selamectin 652
Imidacloprid + Moxidectin 603
Outcome Breakdown
Recovered/Normal
10,456 (36.3%)
Outcome Unknown
9,299 (32.3%)
Ongoing
6,704 (23.3%)
Recovered with Sequela
1,059 (3.7%)
Died
860 (3.0%)
Euthanized
424 (1.5%)
Gender Distribution
Female 15,794 (51.5%)
Male 13,912 (45.4%)
Unknown 839 (2.7%)
Mixed 112 (0.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 991 | |
| 2011 | 1,458 | |
| 2012 | 2,165 | |
| 2013 | 2,224 | |
| 2014 | 2,323 | |
| 2015 | 2,431 | |
| 2016 | 2,298 | |
| 2017 | 2,455 | |
| 2018 | 2,127 | |
| 2019 | 2,109 | |
| 2020 | 1,956 | |
| 2021 | 1,816 | |
| 2022 | 1,684 | |
| 2023 | 1,660 | |
| 2024 | 1,804 | |
| 2025 | 1,156 | |
Chihuahua Pet Health Insights
Chihuahua accounts for 30,657 FDA adverse event reports, ranking #7 by volume among dog breeds, with 1,284 reports (4.2%) coded as a death outcome. Mean age at report: 5.8 years, average weight 4.8 kg (10.6 lbs).
Top reported signs: Vomiting (6,728), Lack of efficacy (ectoparasite) - flea (3,703), Lethargy (see also Central nervous system depression in 'Neurological') (3,541). Most-referenced drug: Milbemycin Oxime + Spinosad (6,085 reports), followed by Spinosad (3,541) and Ivermectin + Pyrantel As Pamoate Salt (1,943).
Outcome coding on 28,802 status-recorded reports is dominated by Recovered/Normal (36.3%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Chihuahua? ▼
There are 30,657 adverse event reports involving Chihuahua in the FDA database, with 1,284 reports involving death (4.2% death rate). Chihuahua ranks #7 by report volume.
What are the most common adverse reactions reported for Chihuahua? ▼
The most commonly reported adverse reactions for Chihuahua are Vomiting (6,728 reports), Lack of efficacy (ectoparasite) - flea (3,703 reports), Lethargy (see also Central nervous system depression in 'Neurological') (3,541 reports), Emesis (2,877 reports), Diarrhoea (2,146 reports).
What drugs are most frequently associated with Chihuahua adverse events? ▼
The drugs most frequently referenced in Chihuahua adverse event reports are Milbemycin Oxime + Spinosad (6,085 reports), Spinosad (3,541 reports), Ivermectin + Pyrantel As Pamoate Salt (1,943 reports), Afoxolaner (1,854 reports), Moxidectin (1,700 reports).
What is the average age of Chihuahua in adverse event reports? ▼
The average age of Chihuahua at the time of adverse event reports is 5.8 years, with an average weight of 4.8 kg (10.6 lbs).
Does a high number of adverse event reports mean Chihuahua is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Chihuahua safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.