Total Reports
6,412
FDA CVM filings
Dog /
FDA CVM · 2025 release 6,412 reports on file
Rottweiler - FDA Adverse Event Profile
Adverse-event records for Rottweiler (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Rottweiler ranks #34 by report volume among dog breeds - 521 of 6,412 reports (8.1%) recorded a death outcome.
- #34
- most-reported dog breed
- 8.1%
- death-coded report share
- 1,299
- Vomiting - top reaction
- 4.5 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
521
of 6,412 reports
Death Rate
8.1%
death-coded share
Avg Age at Report
4.5 yr
38.6 kg avg weight
Death-Coded Outcome Share
Rottweiler death-coded reports 8.1%
Cross-breed median
8.1% of 6,412 rottweiler reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 38.6 kg (85.1 lbs)
Top Reported Reactions
Vomiting 1,299
Lack of efficacy (endoparasite) - heartworm 596
INEFFECTIVE, HEARTWORM LARVAE 594
Lethargy (see also Central nervous system depression in 'Neurological') 585
Emesis 498
Diarrhoea 485
Lack of efficacy - NOS 384
Anorexia 321
Death 266
Lack of efficacy (endoparasite) - hookworm 260
Other abnormal test result NOS 225
Death by euthanasia 220
Lack of efficacy (ectoparasite) - flea 217
Seizure NOS 215
Digestive tract disorder NOS 200
Most Referenced Drugs
Milbemycin Oxime + Spinosad 1,253
Ivermectin + Pyrantel As Pamoate Salt 896
Moxidectin 346
Afoxolaner 330
Pyrantel Pamoate;Sarolaner 325
Spinosad 324
Milbemycin Oxime + Praziquantel 307
Carprofen 300
Fluralaner Chew Tablets 223
Bedinvetmab 193
Melarsomine Dihydrochloride 167
Fluralaner 13.64% 12-Week Chew 141
Deracoxib 127
Gabapentin 124
Ivermectin, Pyrantel 112
Outcome Breakdown
Outcome Unknown
1,892 (32.2%)
Recovered/Normal
1,723 (29.3%)
Ongoing
1,421 (24.2%)
Died
330 (5.6%)
Recovered with Sequela
320 (5.4%)
Euthanized
191 (3.2%)
Gender Distribution
Male 3,265 (50.9%)
Female 2,976 (46.4%)
Unknown 144 (2.2%)
Mixed 27 (0.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 308 | |
| 2011 | 384 | |
| 2012 | 478 | |
| 2013 | 455 | |
| 2014 | 449 | |
| 2015 | 490 | |
| 2016 | 467 | |
| 2017 | 494 | |
| 2018 | 400 | |
| 2019 | 418 | |
| 2020 | 382 | |
| 2021 | 379 | |
| 2022 | 292 | |
| 2023 | 342 | |
| 2024 | 430 | |
| 2025 | 244 | |
Rottweiler Pet Health Insights
Rottweiler accounts for 6,412 FDA adverse event reports, ranking #34 by volume among dog breeds, with 521 reports (8.1%) coded as a death outcome. Mean age at report: 4.5 years, average weight 38.6 kg (85.1 lbs).
Top reported signs: Vomiting (1,299), Lack of efficacy (endoparasite) - heartworm (596), INEFFECTIVE, HEARTWORM LARVAE (594). Most-referenced drug: Milbemycin Oxime + Spinosad (1,253 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (896) and Moxidectin (346).
Outcome coding on 5,877 status-recorded reports is dominated by Outcome Unknown (32.2%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Rottweiler? ▼
There are 6,412 adverse event reports involving Rottweiler in the FDA database, with 521 reports involving death (8.1% death rate). Rottweiler ranks #34 by report volume.
What are the most common adverse reactions reported for Rottweiler? ▼
The most commonly reported adverse reactions for Rottweiler are Vomiting (1,299 reports), Lack of efficacy (endoparasite) - heartworm (596 reports), INEFFECTIVE, HEARTWORM LARVAE (594 reports), Lethargy (see also Central nervous system depression in 'Neurological') (585 reports), Emesis (498 reports).
What drugs are most frequently associated with Rottweiler adverse events? ▼
The drugs most frequently referenced in Rottweiler adverse event reports are Milbemycin Oxime + Spinosad (1,253 reports), Ivermectin + Pyrantel As Pamoate Salt (896 reports), Moxidectin (346 reports), Afoxolaner (330 reports), Pyrantel Pamoate;Sarolaner (325 reports).
What is the average age of Rottweiler in adverse event reports? ▼
The average age of Rottweiler at the time of adverse event reports is 4.5 years, with an average weight of 38.6 kg (85.1 lbs).
Does a high number of adverse event reports mean Rottweiler is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Rottweiler safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.