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Breed profile · FDA CVM July 2026 extract

Rottweiler adverse-event record

Adverse-event filings for Rottweiler (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#34 of 510
by report volume (all breeds)
6,557
FDA CVM reports on file
8.2%
death-coded share of reports
#65 of 275
by death-coded share (≥50 reports)

How the 6,557 reports break down

By recorded gender -- every report on file for Rottweiler, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 433 324.75 216.5 108.25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Rottweiler drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Rottweiler ranks #34 of 510 by total reports (6,557) and #65 of 275 by death-coded share (8.2%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#34
This breed, reports of 510
#65
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Rottweiler has 6,557 reports now versus 6,496 in that prior snapshot: 61 more (0.9%).

Report change
+61
Death-coded reports
+7
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Rottweiler changes

Total Reports

6,557

Highest-reported breed

Deaths Reported

537

of 6,557 reports

Death-coded share of reports

8.2%

High death-coded share

Avg Age at Report

4.5 yr

38.7 kg avg weight

Breed Safety Scorecard

F (36/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate F
8.2%

Share of reports coded as a fatality

Euthanasia rate F
3.1%

Share of reports resulting in euthanasia

Full recovery rate D
26.8%

Share of reports coded "Recovered/Normal"

5-year trend B
-11%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Rottweiler death-coded reports 8.2%
Cross-breed median

8.2% of 6,557 rottweiler reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Rottweiler's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

8% 76th percentile Higher share than 76% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Rottweiler 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Rottweiler among report-volume vs. death-rate peers

Every breed shown has at least 50 filed reports. Volume reflects how often a breed is reported, not how common it is; death rate is the share of a breed's own reports coded as a death outcome.

Source: FDA openFDA Animal & Veterinary Adverse Events database 2×2 strategic matrix plotting 30 entities by Total Reports (X) and Death Rate (%) (Y), with a crosshair dividing the plot into four quadrants. High volume, high death rateLow volume, high death rateHigh volume, low death rateLow volume, low death rate 020,00040,00060,00080,000100,000 0%5%10%15% Total Reports Death Rate (%) Rottweiler vs. all breeds, report volume and death-coded share Retriever - Labrador-93675, 3.7%Crossbred Canine/dog-70591, 3.2%Domestic Shorthair-65226, 7.2%Dog (unknown)-48820, 8.8%Retriever - Golden-35980, 3.7%Shepherd Dog - German-32220, 4.4%Chihuahua-31521, 4.2%Terrier - Yorkshire-24924, 3.7%Shih Tzu-24405, 3.6%Boxer (German Boxer)-19405, 4.4%Beagle-17970, 3.6%Pit Bull-17865, 3.1%Shepherd Dog - Australian-16274, 3.7%Terrier (unspecified)-14058, 3.1%Maltese-13940, 3.2%Dachshund (unspecified)-13512, 4.6%Cat (unknown)-13248, 9.3%Terrier - Jack Russell-10423, 3.7%Collie - Border-10130, 4.3%Siberian Husky-9811, 4.5%Domestic Longhair-9615, 7%Pug-9224, 5.2%Spitz - German Pomeranian-9086, 4.9%Terrier - Bull - American Pit-8769, 4.7%Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)-7871, 3.6%Terrier - Boston-7737, 4.5%Spaniel - Cocker American-7640, 4%Domestic (unspecified)-7576, 13.4%Poodle (unspecified)-7534, 3.4%Schnauzer - Miniature-7513, 4.4%
Source: FDA openFDA Animal & Veterinary Adverse Events database
Average weight at time of report: 38.7 kg (85.3 lbs)

Top Reported Reactions

Vomiting 1,314
Lack of efficacy (endoparasite) - heartworm 621
INEFFECTIVE, HEARTWORM LARVAE 594
Lethargy (see also Central nervous system depression in 'Neurological') 585
Emesis 499
Diarrhoea 494
Lack of efficacy - NOS 388
Anorexia 325
Death 272
Lack of efficacy (endoparasite) - hookworm 268
Other abnormal test result NOS 232
Death by euthanasia 229
Seizure NOS 222
Lack of efficacy (ectoparasite) - flea 220
Digestive tract disorder NOS 201

Most Referenced Drugs

Milbemycin Oxime + Spinosad 1,255
Ivermectin + Pyrantel As Pamoate Salt 920
Moxidectin 358
Pyrantel Pamoate;Sarolaner 356
Afoxolaner 334
Spinosad 324
Milbemycin Oxime + Praziquantel 313
Carprofen 308
Fluralaner Chew Tablets 223
Bedinvetmab 211
Melarsomine Dihydrochloride 167
Fluralaner 13.64% 12-Week Chew 148
Gabapentin 133
Deracoxib 127
Ivermectin, Pyrantel 112

Outcome Breakdown

Outcome Unknown
1,925 (32.0%)
Recovered/Normal
1,757 (29.2%)
Ongoing
1,482 (24.6%)
Died
337 (5.6%)
Recovered with Sequela
321 (5.3%)
Euthanized
200 (3.3%)

Gender Distribution

Male 3,343 (51.0%)
Female 3,039 (46.3%)
Unknown 147 (2.2%)
Mixed 28 (0.4%)

Reports by Year

Year Reports Trend
2010 308
2011 384
2012 478
2013 455
2014 449
2015 490
2016 467
2017 494
2018 400
2019 418
2020 382
2021 379
2022 292
2023 343
2024 433
2025 338
2026 47

Rottweiler: high death-coded share in the FDA CVM extract

Signature read: 6,557 reports place Rottweiler in the upper third of breed filing volume (#34 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Rottweiler sits at #34 of 510 by report volume among all breeds and #30 of 298 among dog breeds, with 6,557 reports and 537 (8.2%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #65 of 275. Mean age at report: 4.5 years, average weight 38.7 kg (85.3 lbs).

Top reported signs: Vomiting (1,314), Lack of efficacy (endoparasite) - heartworm (621), INEFFECTIVE, HEARTWORM LARVAE (594). Most-referenced drug: Milbemycin Oxime + Spinosad (1,255 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (920) and Moxidectin (358).

Outcome coding on 6,022 status-recorded reports is dominated by Outcome Unknown (32.0%). Annual submissions ranged 47-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Spaniel - King Charles Cavalier
6,052 reports · 4.2% death-coded
Bichon Frise
7,085 reports · 3.9% death-coded
Dog (other)
5,922 reports · 4.3% death-coded
Bulldog
7,268 reports · 4.7% death-coded
Bulldog - French
7,272 reports · 4.4% death-coded
Schnauzer - Miniature
7,513 reports · 4.4% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Rottweiler drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (8.2% death-coded here).

Thoroughbred 8.2% · Horse Siamese 8.1% · Cat Scottish Fold Shorthair 8.3% · Cat Crossbred Equine/horse 7.9% · Horse

Similar average weight

Nearest other-species breeds by reported average weight (38.7 kg here).

Vietnamese Pot Bellied 37.5 kg · Pig Wolf Hybrid 37.3 kg · Other Canids Sheep (unknown) 40.9 kg · Sheep Boer 41.2 kg · Goat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Rottweiler? ▼
There are 6,557 adverse event reports involving Rottweiler in the FDA database, of which 537 were death-coded (8.2% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Rottweiler ranks #34 of 510 by report volume among all breeds PlainBreed indexes (#30 of 298 among dog breeds).
Where does Rottweiler sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Rottweiler is #34 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #30 of 298. Among breeds with at least 50 reports, its death-coded share ranks #65 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Rottweiler? ▼
The most commonly reported adverse reactions for Rottweiler are Vomiting (1,314 reports), Lack of efficacy (endoparasite) - heartworm (621 reports), INEFFECTIVE, HEARTWORM LARVAE (594 reports), Lethargy (see also Central nervous system depression in 'Neurological') (585 reports), Emesis (499 reports).
What drugs are most frequently associated with Rottweiler adverse events? ▼
The drugs most frequently referenced in Rottweiler adverse event reports are Milbemycin Oxime + Spinosad (1,255 reports), Ivermectin + Pyrantel As Pamoate Salt (920 reports), Moxidectin (358 reports), Pyrantel Pamoate;Sarolaner (356 reports), Afoxolaner (334 reports).
What is the average age of Rottweiler in adverse event reports? ▼
The average age of Rottweiler at the time of adverse event reports is 4.5 years, with an average weight of 38.7 kg (85.3 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Rottweiler (Dog), extract as of July 2026 extract. 6,557 reports · 537 death-coded (8.2% of reports, not a mortality rate) · #34 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →