Cat /

Siamese

2,946 adverse event reports submitted to the FDA

Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
2,946
Total Reports
244
Deaths Reported
830.0%
Death Rate
7.4 yr
Avg Age at Report
Average weight at time of report: 4.7 kg (10.4 lbs)

Top Reported Reactions

Vomiting 427
Lethargy (see also Central nervous system depression in 'Neurological') 322
Lack of efficacy (ectoparasite) - flea 231
Emesis 226
Anorexia 203
Behavioural disorder NOS 185
Weight loss 165
Application site hair loss 157
Lack of efficacy - NOS 153
Application site alopecia 150
Ataxia 142
Diarrhoea 133
Not eating 128
Hypersalivation 121
Death 117

Most Referenced Drugs

Spinosad 429
Selamectin 371
Fluralaner Spot-On Solution 203
Frunevetmab 191
Cefovecin 188
Imidacloprid + Moxidectin 163
Nitenpyram 163
Buprenorphine 157
Selamectin;Sarolaner 143
Maropitant Citrate 115
Emodepside + Praziquantel 92
Robenacoxib 80
Mirtazapine 68
Velagliflozin Proline Monohydrate 65
Bexagliflozin 60

Outcome Breakdown

Recovered/Normal
843 (30.1%)
Ongoing
842 (30.1%)
Outcome Unknown
839 (30.0%)
Died
140 (5.0%)
Euthanized
104 (3.7%)
Recovered with Sequela
32 (1.1%)

Gender Distribution

Male 1,577 (53.5%)
Female 1,322 (44.9%)
Unknown 29 (1.0%)
Mixed 18 (0.6%)

Reports by Year

Year Reports Trend
2010 90
2011 82
2012 183
2013 225
2014 207
2015 202
2016 176
2017 211
2018 184
2019 180
2020 173
2021 149
2022 166
2023 239
2024 320
2025 159

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #64 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.