Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
12,555
Total Reports
1,163
Deaths Reported
930.0%
Death Rate
6.8 yr
Avg Age at Report
Average weight at time of report: 4.6 kg (10.1 lbs)
Top Reported Reactions
Lack of efficacy (ectoparasite) - flea 1,903
Vomiting 1,102
Lack of efficacy - NOS 1,007
Death 762
Behavioural disorder NOS 701
Lethargy (see also Central nervous system depression in 'Neurological') 535
Hypersalivation 457
Anorexia 446
Diarrhoea 395
Emesis 370
Hyperactivity 354
Application site alopecia 348
Death by euthanasia 314
Weight loss 298
Not eating 289
Most Referenced Drugs
Nitenpyram 1,140
Spinosad 1,076
Buprenorphine 1,033
Selamectin 991
Imidacloprid + Moxidectin 927
Fluralaner Spot-On Solution 865
Bexagliflozin 508
Emodepside + Praziquantel 496
Praziquantel 447
Robenacoxib 423
Eprinomectin + Esafoxolaner + Praziquantel 331
Cyclosporine 274
Velagliflozin Proline Monohydrate 258
Fluralaner/Moxidectin Spot-On 224
Mirtazapine 210
Outcome Breakdown
Outcome Unknown
6,241 (52.8%)
Recovered/Normal
2,554 (21.6%)
Ongoing
1,810 (15.3%)
Died
862 (7.3%)
Euthanized
304 (2.6%)
Recovered with Sequela
50 (0.4%)
Gender Distribution
Unknown 7,463 (59.4%)
Male 2,532 (20.2%)
Female 2,390 (19.0%)
Mixed 170 (1.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 464 | |
| 2011 | 392 | |
| 2012 | 770 | |
| 2013 | 771 | |
| 2014 | 690 | |
| 2015 | 623 | |
| 2016 | 542 | |
| 2017 | 653 | |
| 2018 | 647 | |
| 2019 | 669 | |
| 2020 | 751 | |
| 2021 | 810 | |
| 2022 | 921 | |
| 2023 | 1,426 | |
| 2024 | 1,579 | |
| 2025 | 847 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #17 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.