Total Reports
12,555
FDA CVM filings
Cat /
FDA CVM · 2025 release 12,555 reports on file
Cat (unknown) - FDA Adverse Event Profile
Adverse-event records for Cat (unknown) (Cat) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Cat (unknown) ranks #17 by report volume among cat breeds - 1,163 of 12,555 reports (9.3%) recorded a death outcome.
- #17
- most-reported cat breed
- 9.3%
- death-coded report share
- 1,903
- Lack of efficacy (ectoparasite) - flea - top reaction
- 6.8 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
1,163
of 12,555 reports
Death Rate
9.3%
death-coded share
Avg Age at Report
6.8 yr
4.6 kg avg weight
Death-Coded Outcome Share
Cat (unknown) death-coded reports 9.3%
Cross-breed median
9.3% of 12,555 cat (unknown) reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 4.6 kg (10.1 lbs)
Top Reported Reactions
Lack of efficacy (ectoparasite) - flea 1,903
Vomiting 1,102
Lack of efficacy - NOS 1,007
Death 762
Behavioural disorder NOS 701
Lethargy (see also Central nervous system depression in 'Neurological') 535
Hypersalivation 457
Anorexia 446
Diarrhoea 395
Emesis 370
Hyperactivity 354
Application site alopecia 348
Death by euthanasia 314
Weight loss 298
Not eating 289
Most Referenced Drugs
Nitenpyram 1,140
Spinosad 1,076
Buprenorphine 1,033
Selamectin 991
Imidacloprid + Moxidectin 927
Fluralaner Spot-On Solution 865
Bexagliflozin 508
Emodepside + Praziquantel 496
Praziquantel 447
Robenacoxib 423
Eprinomectin + Esafoxolaner + Praziquantel 331
Cyclosporine 274
Velagliflozin Proline Monohydrate 258
Fluralaner/Moxidectin Spot-On 224
Mirtazapine 210
Outcome Breakdown
Outcome Unknown
6,241 (52.8%)
Recovered/Normal
2,554 (21.6%)
Ongoing
1,810 (15.3%)
Died
862 (7.3%)
Euthanized
304 (2.6%)
Recovered with Sequela
50 (0.4%)
Gender Distribution
Unknown 7,463 (59.4%)
Male 2,532 (20.2%)
Female 2,390 (19.0%)
Mixed 170 (1.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 464 | |
| 2011 | 392 | |
| 2012 | 770 | |
| 2013 | 771 | |
| 2014 | 690 | |
| 2015 | 623 | |
| 2016 | 542 | |
| 2017 | 653 | |
| 2018 | 647 | |
| 2019 | 669 | |
| 2020 | 751 | |
| 2021 | 810 | |
| 2022 | 921 | |
| 2023 | 1,426 | |
| 2024 | 1,579 | |
| 2025 | 847 | |
Cat (unknown) Pet Health Insights
Cat (unknown) accounts for 12,555 FDA adverse event reports, ranking #17 by volume among cat breeds, with 1,163 reports (9.3%) coded as a death outcome. Mean age at report: 6.8 years, average weight 4.6 kg (10.1 lbs).
Top reported signs: Lack of efficacy (ectoparasite) - flea (1,903), Vomiting (1,102), Lack of efficacy - NOS (1,007). Most-referenced drug: Nitenpyram (1,140 reports), followed by Spinosad (1,076) and Buprenorphine (1,033).
Outcome coding on 11,821 status-recorded reports is dominated by Outcome Unknown (52.8%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Cat Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Cat (unknown)? ▼
There are 12,555 adverse event reports involving Cat (unknown) in the FDA database, with 1,163 reports involving death (9.3% death rate). Cat (unknown) ranks #17 by report volume.
What are the most common adverse reactions reported for Cat (unknown)? ▼
The most commonly reported adverse reactions for Cat (unknown) are Lack of efficacy (ectoparasite) - flea (1,903 reports), Vomiting (1,102 reports), Lack of efficacy - NOS (1,007 reports), Death (762 reports), Behavioural disorder NOS (701 reports).
What drugs are most frequently associated with Cat (unknown) adverse events? ▼
The drugs most frequently referenced in Cat (unknown) adverse event reports are Nitenpyram (1,140 reports), Spinosad (1,076 reports), Buprenorphine (1,033 reports), Selamectin (991 reports), Imidacloprid + Moxidectin (927 reports).
What is the average age of Cat (unknown) in adverse event reports? ▼
The average age of Cat (unknown) at the time of adverse event reports is 6.8 years, with an average weight of 4.6 kg (10.1 lbs).
Does a high number of adverse event reports mean Cat (unknown) is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Cat (unknown) safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.