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2026 FDA CVM data 2,029 reports on file official source

Chow Chow — FDA Adverse Event Profile

Adverse-event records and label data for Chow Chow (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 146 109.5 73 36.5 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Chow Chow drawn from FDA CVM filings.

Chow Chow (Dog) has 2,029 FDA adverse event reports on record, with 130 deaths reported (640.0% death rate) — ranking #80 by report volume. The most frequently reported reaction is Vomiting (337 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 7.4 years.

Total Reports

2,029

FDA CVM filings

Deaths Reported

130

of 2,029 reports

Death Rate

640.0%

death-coded share

Avg Age at Report

7.4 yr

24.8 kg avg weight

Death-Coded Outcome Share

Chow Chow death-coded reports 100.0%
Database median

640.0% of 2,029 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 24.8 kg (54.7 lbs)

Top Reported Reactions

Vomiting 337
Emesis 184
INEFFECTIVE, HEARTWORM LARVAE 183
Lethargy (see also Central nervous system depression in 'Neurological') 180
Diarrhoea 147
Lack of efficacy - NOS 133
Lack of efficacy (ectoparasite) - flea 106
Lack of efficacy (endoparasite) - heartworm 100
Anorexia 92
Seizure NOS 70
Death by euthanasia 69
Other abnormal test result NOS 62
Ataxia 60
Pruritus 58
Lack of efficacy (endoparasite) - hookworm 57

Most Referenced Drugs

Milbemycin Oxime + Spinosad 419
Ivermectin + Pyrantel As Pamoate Salt 162
Spinosad 159
Carprofen 91
Afoxolaner 87
Moxidectin 77
Bedinvetmab 73
Oclacitinib Maleate 65
Fluralaner Chew Tablets 64
Pyrantel Pamoate;Sarolaner 63
Grapiprant 56
Milbemycin Oxime + Praziquantel 52
Selamectin 50
Trilostane 50
Gabapentin 40

Outcome Breakdown

Outcome Unknown
605 (32.2%)
Recovered/Normal
598 (31.8%)
Ongoing
416 (22.1%)
Recovered with Sequela
130 (6.9%)
Died
69 (3.7%)
Euthanized
61 (3.2%)

Gender Distribution

Male 1,015 (50.0%)
Female 981 (48.3%)
Unknown 25 (1.2%)
Mixed 8 (0.4%)

Reports by Year

Year Reports Trend
2010 96
2011 134
2012 226
2013 174
2014 174
2015 171
2016 162
2017 186
2018 146
2019 100
2020 85
2021 74
2022 78
2023 76
2024 99
2025 48
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Chow Chow sits in the registered size-class taxonomy. Average reported weight: 24.8 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Chow Chow Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Chow Chow accounts for 2,029 submitted reports and currently ranks #80 by report volume within the dog population. Of those reports, 130 involved a death outcome — a 640.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 7.4 years, with an average recorded body weight of 24.8 kg (54.7 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Chow Chow are Vomiting (337 reports), Emesis (184 reports), INEFFECTIVE, HEARTWORM LARVAE (183 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 419 reports and is the single most-referenced drug, followed by Ivermectin + Pyrantel As Pamoate Salt (162) and Spinosad (159). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 1,879 reports with a recorded status is dominated by Outcome Unknown (32.2% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Chow Chow Adverse Event Data

Chow Chow has a moderate volume of adverse event reports (2,029). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 640.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 419 reports. This may indicate widespread use of the medication rather than a specific safety concern for Chow Chow.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Chow Chow?
There are 2,029 adverse event reports involving Chow Chow in the FDA database, with 130 reports involving death (640.0% death rate). Chow Chow ranks #80 by report volume.
What are the most common adverse reactions reported for Chow Chow?
The most commonly reported adverse reactions for Chow Chow are Vomiting (337 reports), Emesis (184 reports), INEFFECTIVE, HEARTWORM LARVAE (183 reports), Lethargy (see also Central nervous system depression in 'Neurological') (180 reports), Diarrhoea (147 reports).
What drugs are most frequently associated with Chow Chow adverse events?
The drugs most frequently referenced in Chow Chow adverse event reports are Milbemycin Oxime + Spinosad (419 reports), Ivermectin + Pyrantel As Pamoate Salt (162 reports), Spinosad (159 reports), Carprofen (91 reports), Afoxolaner (87 reports).
What is the average age of Chow Chow in adverse event reports?
The average age of Chow Chow at the time of adverse event reports is 7.4 years, with an average weight of 24.8 kg (54.7 lbs).
Does a high number of adverse event reports mean Chow Chow is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Chow Chow safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Chow Chow ranks #80 by total report volume. Death rate (640.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial