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Breed profile · FDA CVM July 2026 extract

Chow Chow adverse-event record

Adverse-event filings for Chow Chow (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#80 of 510
by report volume (all breeds)
2,065
FDA CVM reports on file
6.4%
death-coded share of reports
#96 of 275
by death-coded share (≥50 reports)

How the 2,065 reports break down

By recorded gender -- every report on file for Chow Chow, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 100 75 50 25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Chow Chow drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Chow Chow ranks #80 of 510 by total reports (2,065) and #96 of 275 by death-coded share (6.4%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#80
This breed, reports of 510
#96
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chow Chow has 2,065 reports now versus 2,049 in that prior snapshot: 16 more (0.8%).

Report change
+16
Death-coded reports
+2
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chow Chow changes

Total Reports

2,065

High report volume

Deaths Reported

133

of 2,065 reports

Death-coded share of reports

6.4%

Above-median death-coded share

Avg Age at Report

7.4 yr

24.8 kg avg weight

Breed Safety Scorecard

D (41/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate F
6.4%

Share of reports coded as a fatality

Euthanasia rate F
3.0%

Share of reports resulting in euthanasia

Full recovery rate C-
29.3%

Share of reports coded "Recovered/Normal"

5-year trend C
+0%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Chow Chow death-coded reports 6.4%
Cross-breed median

6.4% of 2,065 chow chow reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Chow Chow's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

6% 65th percentile Higher share than 65% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Chow Chow 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 24.8 kg (54.7 lbs)

Top Reported Reactions

Vomiting 340
Emesis 184
INEFFECTIVE, HEARTWORM LARVAE 183
Lethargy (see also Central nervous system depression in 'Neurological') 180
Diarrhoea 147
Lack of efficacy - NOS 139
Lack of efficacy (ectoparasite) - flea 108
Lack of efficacy (endoparasite) - heartworm 106
Anorexia 93
Seizure NOS 72
Death by euthanasia 69
Ataxia 62
Other abnormal test result NOS 62
Pruritus 61
Lack of efficacy (endoparasite) - hookworm 59

Most Referenced Drugs

Milbemycin Oxime + Spinosad 420
Ivermectin + Pyrantel As Pamoate Salt 164
Spinosad 159
Carprofen 93
Afoxolaner 89
Bedinvetmab 82
Moxidectin 79
Oclacitinib Maleate 70
Pyrantel Pamoate;Sarolaner 67
Fluralaner Chew Tablets 64
Grapiprant 56
Milbemycin Oxime + Praziquantel 53
Selamectin 51
Trilostane 50
Gabapentin 42

Outcome Breakdown

Outcome Unknown
615 (32.1%)
Recovered/Normal
605 (31.6%)
Ongoing
431 (22.5%)
Recovered with Sequela
131 (6.8%)
Died
72 (3.8%)
Euthanized
61 (3.2%)

Gender Distribution

Male 1,032 (50.0%)
Female 1,000 (48.4%)
Unknown 25 (1.2%)
Mixed 8 (0.4%)

Reports by Year

Year Reports Trend
2010 96
2011 134
2012 226
2013 174
2014 174
2015 171
2016 162
2017 186
2018 146
2019 100
2020 85
2021 74
2022 78
2023 78
2024 100
2025 74
2026 7

Chow Chow: high-volume FDA adverse-event cohort

Signature read: 2,065 reports place Chow Chow in the upper third of breed filing volume (#80 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Chow Chow sits at #80 of 510 by report volume among all breeds and #66 of 298 among dog breeds, with 2,065 reports and 133 (6.4%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #96 of 275. Mean age at report: 7.4 years, average weight 24.8 kg (54.7 lbs).

Top reported signs: Vomiting (340), Emesis (184), INEFFECTIVE, HEARTWORM LARVAE (183). Most-referenced drug: Milbemycin Oxime + Spinosad (420 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (164) and Spinosad (159).

Outcome coding on 1,915 status-recorded reports is dominated by Outcome Unknown (32.1%). Annual submissions ranged 7-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne))
2,120 reports · 4.5% death-coded
Terrier - Cairn
1,953 reports · 4.7% death-coded
Brittany
1,879 reports · 2.8% death-coded
Spaniel - Springer English
2,268 reports · 4.0% death-coded
Shepherd Dog - Belgian Malinois
1,741 reports · 3.0% death-coded
Catahoula Leopard Dog
2,402 reports · 2.2% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Chow Chow drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (6.4% death-coded here).

Crossbred Feline/cat 6.3% · Cat Domestic Longhair 7.0% · Cat Snowshoe 7.0% · Cat Warmblood (unspecified) 7.0% · Horse

Similar average weight

Nearest other-species breeds by reported average weight (24.8 kg here).

Mixed (Sheep) 24.9 kg · Sheep Crossbred Caprine/goat 21.7 kg · Goat Pygmy 20.3 kg · Goat Fish (other) 32.4 kg · Fish

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Chow Chow? ▼
There are 2,065 adverse event reports involving Chow Chow in the FDA database, of which 133 were death-coded (6.4% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Chow Chow ranks #80 of 510 by report volume among all breeds PlainBreed indexes (#66 of 298 among dog breeds).
Where does Chow Chow sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Chow Chow is #80 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #66 of 298. Among breeds with at least 50 reports, its death-coded share ranks #96 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Chow Chow? ▼
The most commonly reported adverse reactions for Chow Chow are Vomiting (340 reports), Emesis (184 reports), INEFFECTIVE, HEARTWORM LARVAE (183 reports), Lethargy (see also Central nervous system depression in 'Neurological') (180 reports), Diarrhoea (147 reports).
What drugs are most frequently associated with Chow Chow adverse events? ▼
The drugs most frequently referenced in Chow Chow adverse event reports are Milbemycin Oxime + Spinosad (420 reports), Ivermectin + Pyrantel As Pamoate Salt (164 reports), Spinosad (159 reports), Carprofen (93 reports), Afoxolaner (89 reports).
What is the average age of Chow Chow in adverse event reports? ▼
The average age of Chow Chow at the time of adverse event reports is 7.4 years, with an average weight of 24.8 kg (54.7 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chow Chow (Dog), extract as of July 2026 extract. 2,065 reports · 133 death-coded (6.4% of reports, not a mortality rate) · #80 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →