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Breed profile · FDA CVM July 2026 extract

Shiba Inu adverse-event record

Adverse-event filings for Shiba Inu (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#84 of 510
by report volume (all breeds)
1,673
FDA CVM reports on file
2.5%
death-coded share of reports
#252 of 275
by death-coded share (≥50 reports)

How the 1,673 reports break down

By recorded gender -- every report on file for Shiba Inu, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 128 96 64 32 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Shiba Inu drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Shiba Inu ranks #84 of 510 by total reports (1,673) and #252 of 275 by death-coded share (2.5%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#84
This breed, reports of 510
#252
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Shiba Inu has 1,673 reports now versus 1,652 in that prior snapshot: 21 more (1.3%).

Report change
+21
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Shiba Inu changes

Total Reports

1,673

High report volume

Deaths Reported

41

of 1,673 reports

Death-coded share of reports

2.5%

Lowest death-coded share

Avg Age at Report

5.5 yr

12.1 kg avg weight

Breed Safety Scorecard

B+ (77/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate A+
2.5%

Share of reports coded as a fatality

Euthanasia rate A
1.4%

Share of reports resulting in euthanasia

Full recovery rate B+
35.6%

Share of reports coded "Recovered/Normal"

5-year trend D
+14%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Shiba Inu death-coded reports 2.5%
Cross-breed median

2.5% of 1,673 shiba inu reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Shiba Inu's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

2% 8th percentile Higher share than 8% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Shiba Inu 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 12.1 kg (26.7 lbs)

Top Reported Reactions

Vomiting 339
Lethargy (see also Central nervous system depression in 'Neurological') 196
Diarrhoea 145
Emesis 122
Seizure NOS 110
Lack of efficacy - NOS 86
Behavioural disorder NOS 75
Lack of efficacy (ectoparasite) - flea 74
Anorexia 68
Lack of efficacy (endoparasite) - hookworm 66
Ataxia 64
Panting 54
Shaking 50
Other abnormal test result NOS 38
Digestive tract disorder NOS 38

Most Referenced Drugs

Milbemycin Oxime + Spinosad 324
Pyrantel Pamoate;Sarolaner 141
Afoxolaner 134
Ivermectin + Pyrantel As Pamoate Salt 129
Oclacitinib Maleate 103
Spinosad 88
Fluralaner Chew Tablets 68
Moxidectin 66
Milbemycin Oxime + Praziquantel 60
Bedinvetmab 53
Fluralaner 13.64% 12-Week Chew 51
Sarolaner 33
Carprofen 31
Trilostane 26
Cyclosporine 24

Outcome Breakdown

Recovered/Normal
596 (37.6%)
Outcome Unknown
472 (29.8%)
Ongoing
434 (27.4%)
Recovered with Sequela
42 (2.6%)
Euthanized
23 (1.5%)
Died
18 (1.1%)

Gender Distribution

Female 827 (49.4%)
Male 802 (47.9%)
Unknown 35 (2.1%)
Mixed 9 (0.5%)

Reports by Year

Year Reports Trend
2010 36
2011 51
2012 108
2013 110
2014 130
2015 125
2016 130
2017 115
2018 97
2019 81
2020 113
2021 97
2022 107
2023 128
2024 117
2025 111
2026 17

Shiba Inu: low death-coded share in the FDA CVM extract

Signature read: Shiba Inu's 2.5% death-coded share is in the lower third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Shiba Inu sits at #84 of 510 by report volume among all breeds and #70 of 298 among dog breeds, with 1,673 reports and 41 (2.5%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #252 of 275. Mean age at report: 5.5 years, average weight 12.1 kg (26.7 lbs).

Top reported signs: Vomiting (339), Lethargy (see also Central nervous system depression in 'Neurological') (196), Diarrhoea (145). Most-referenced drug: Milbemycin Oxime + Spinosad (324 reports), followed by Pyrantel Pamoate;Sarolaner (141) and Afoxolaner (134).

Outcome coding on 1,585 status-recorded reports is dominated by Recovered/Normal (37.6%). Annual submissions ranged 17-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Terrier - Irish Soft-coated Wheaten
1,654 reports · 3.3% death-coded
Corgi - Welsh Pembroke
1,624 reports · 4.2% death-coded
Shepherd Dog - Belgian Malinois
1,741 reports · 3.0% death-coded
Pointer (unspecified)
1,595 reports · 2.7% death-coded
Pointing Dog - Hungarian Short-haired (Vizsla)
1,526 reports · 4.3% death-coded
Terrier - Scottish
1,489 reports · 5.8% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Shiba Inu drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (2.5% death-coded here).

Hanovarian 2.2% · Horse Warmblood - Dutch 2.7% · Horse Oldenburg 2.8% · Horse Birman (Sacred Birman) 3.1% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (12.1 kg here).

Monkey (unspecified) 11.6 kg · Monkey Primate (other) 10.1 kg · Primate Wild cat 14.5 kg · Cat Nigerian Dwarf 7.5 kg · Goat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Shiba Inu? ▼
There are 1,673 adverse event reports involving Shiba Inu in the FDA database, of which 41 were death-coded (2.5% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Shiba Inu ranks #84 of 510 by report volume among all breeds PlainBreed indexes (#70 of 298 among dog breeds).
Where does Shiba Inu sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Shiba Inu is #84 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #70 of 298. Among breeds with at least 50 reports, its death-coded share ranks #252 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Shiba Inu? ▼
The most commonly reported adverse reactions for Shiba Inu are Vomiting (339 reports), Lethargy (see also Central nervous system depression in 'Neurological') (196 reports), Diarrhoea (145 reports), Emesis (122 reports), Seizure NOS (110 reports).
What drugs are most frequently associated with Shiba Inu adverse events? ▼
The drugs most frequently referenced in Shiba Inu adverse event reports are Milbemycin Oxime + Spinosad (324 reports), Pyrantel Pamoate;Sarolaner (141 reports), Afoxolaner (134 reports), Ivermectin + Pyrantel As Pamoate Salt (129 reports), Oclacitinib Maleate (103 reports).
What is the average age of Shiba Inu in adverse event reports? ▼
The average age of Shiba Inu at the time of adverse event reports is 5.5 years, with an average weight of 12.1 kg (26.7 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Shiba Inu (Dog), extract as of July 2026 extract. 1,673 reports · 41 death-coded (2.5% of reports, not a mortality rate) · #84 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →