Total Reports
8,232
FDA CVM filings
Dog /
FDA CVM · 2025 release 8,232 reports on file
Terrier - Bull - American Pit - FDA Adverse Event Profile
Adverse-event records for Terrier - Bull - American Pit (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Terrier - Bull - American Pit's FDA record: #24 most-reported dog breed, 8,232 total reports, 4.5% death-coded (374 reports).
- #24
- most-reported dog breed
- 4.5%
- death-coded report share
- 1,543
- Vomiting - top reaction
- 4.8 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
374
of 8,232 reports
Death Rate
4.5%
death-coded share
Avg Age at Report
4.8 yr
27.7 kg avg weight
Death-Coded Outcome Share
Terrier - Bull - American Pit death-coded reports 4.5%
Cross-breed median
4.5% of 8,232 terrier - bull - american pit reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 27.7 kg (61.1 lbs)
Top Reported Reactions
Vomiting 1,543
Lack of efficacy (endoparasite) - heartworm 1,016
Hives (see also 'Skin') 810
Lethargy (see also Central nervous system depression in 'Neurological') 678
Facial swelling (see also 'Skin') 600
Diarrhoea 588
Anaphylaxis 407
Lack of efficacy - NOS 369
Seizure NOS 343
Emesis 285
Lack of efficacy (endoparasite) - hookworm 282
Lethargy (see also Central nervous system depression in Neurological) 254
Anorexia 235
Ataxia 221
Erythema (for urticaria see Immune SOC) 207
Most Referenced Drugs
Moxidectin 2,705
Pyrantel Pamoate;Sarolaner 1,554
Oclacitinib Maleate 1,331
Bedinvetmab 758
Carprofen 484
Sarolaner 460
Melarsomine Dihydrochloride 434
Anti-Il31 Mab Mcs Lot #1283563 314
Maropitant Citrate 300
Gabapentin 278
Prednisone 273
Milbemycin Oxime + Spinosad 257
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 232
Selamectin 173
Diphenhydramine Hcl 158
Outcome Breakdown
Ongoing
5,054 (61.6%)
Recovered/Normal
1,817 (22.2%)
Outcome Unknown
921 (11.2%)
Euthanized
199 (2.4%)
Died
176 (2.1%)
Recovered with Sequela
32 (0.4%)
Gender Distribution
Female 4,152 (50.4%)
Male 3,923 (47.7%)
Unknown 115 (1.4%)
Mixed 42 (0.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 27 | |
| 2011 | 114 | |
| 2012 | 198 | |
| 2013 | 129 | |
| 2014 | 233 | |
| 2015 | 303 | |
| 2016 | 344 | |
| 2017 | 522 | |
| 2018 | 539 | |
| 2019 | 581 | |
| 2020 | 717 | |
| 2021 | 789 | |
| 2022 | 787 | |
| 2023 | 997 | |
| 2024 | 1,246 | |
| 2025 | 706 | |
Terrier - Bull - American Pit Pet Health Insights
Terrier - Bull - American Pit accounts for 8,232 FDA adverse event reports, ranking #24 by volume among dog breeds, with 374 reports (4.5%) coded as a death outcome. Mean age at report: 4.8 years, average weight 27.7 kg (61.1 lbs).
Top reported signs: Vomiting (1,543), Lack of efficacy (endoparasite) - heartworm (1,016), Hives (see also 'Skin') (810). Most-referenced drug: Moxidectin (2,705 reports), followed by Pyrantel Pamoate;Sarolaner (1,554) and Oclacitinib Maleate (1,331).
Outcome coding on 8,199 status-recorded reports is dominated by Ongoing (61.6%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Spitz - German Pomeranian
8,853 reports · 5.0% death rate
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)
7,541 reports · 3.6% death rate
Spaniel - Cocker American
7,534 reports · 4.0% death rate
Terrier - Boston
7,526 reports · 4.6% death rate
Pug
9,020 reports · 5.1% death rate
Schnauzer - Miniature
7,307 reports · 4.4% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Terrier - Bull - American Pit? ▼
There are 8,232 adverse event reports involving Terrier - Bull - American Pit in the FDA database, with 374 reports involving death (4.5% death rate). Terrier - Bull - American Pit ranks #24 by report volume.
What are the most common adverse reactions reported for Terrier - Bull - American Pit? ▼
The most commonly reported adverse reactions for Terrier - Bull - American Pit are Vomiting (1,543 reports), Lack of efficacy (endoparasite) - heartworm (1,016 reports), Hives (see also 'Skin') (810 reports), Lethargy (see also Central nervous system depression in 'Neurological') (678 reports), Facial swelling (see also 'Skin') (600 reports).
What drugs are most frequently associated with Terrier - Bull - American Pit adverse events? ▼
The drugs most frequently referenced in Terrier - Bull - American Pit adverse event reports are Moxidectin (2,705 reports), Pyrantel Pamoate;Sarolaner (1,554 reports), Oclacitinib Maleate (1,331 reports), Bedinvetmab (758 reports), Carprofen (484 reports).
What is the average age of Terrier - Bull - American Pit in adverse event reports? ▼
The average age of Terrier - Bull - American Pit at the time of adverse event reports is 4.8 years, with an average weight of 27.7 kg (61.1 lbs).
Does a high number of adverse event reports mean Terrier - Bull - American Pit is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Bull - American Pit safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.