Dog /
2026 FDA CVM data 8,232 reports on file official source

Terrier - Bull - American Pit — FDA Adverse Event Profile

Adverse-event records and label data for Terrier - Bull - American Pit (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

Verify with FDA CVM →
Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 1,246 934.5 623 311.5 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Terrier - Bull - American Pit drawn from FDA CVM filings.

Terrier - Bull - American Pit (Dog) has 8,232 FDA adverse event reports on record, with 374 deaths reported (450.0% death rate) — ranking #24 by report volume. The most frequently reported reaction is Vomiting (1,543 cases). The top associated drug is Moxidectin. Average age at report: 4.8 years.

Total Reports

8,232

FDA CVM filings

Deaths Reported

374

of 8,232 reports

Death Rate

450.0%

death-coded share

Avg Age at Report

4.8 yr

27.7 kg avg weight

Death-Coded Outcome Share

Terrier - Bull - American Pit death-coded reports 100.0%
Database median

450.0% of 8,232 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 27.7 kg (61.1 lbs)

Top Reported Reactions

Vomiting 1,543
Lack of efficacy (endoparasite) - heartworm 1,016
Hives (see also 'Skin') 810
Lethargy (see also Central nervous system depression in 'Neurological') 678
Facial swelling (see also 'Skin') 600
Diarrhoea 588
Anaphylaxis 407
Lack of efficacy - NOS 369
Seizure NOS 343
Emesis 285
Lack of efficacy (endoparasite) - hookworm 282
Lethargy (see also Central nervous system depression in Neurological) 254
Anorexia 235
Ataxia 221
Erythema (for urticaria see Immune SOC) 207

Most Referenced Drugs

Moxidectin 2,705
Pyrantel Pamoate;Sarolaner 1,554
Oclacitinib Maleate 1,331
Bedinvetmab 758
Carprofen 484
Sarolaner 460
Melarsomine Dihydrochloride 434
Anti-Il31 Mab Mcs Lot #1283563 314
Maropitant Citrate 300
Gabapentin 278
Prednisone 273
Milbemycin Oxime + Spinosad 257
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 232
Selamectin 173
Diphenhydramine Hcl 158

Outcome Breakdown

Ongoing
5,054 (61.6%)
Recovered/Normal
1,817 (22.2%)
Outcome Unknown
921 (11.2%)
Euthanized
199 (2.4%)
Died
176 (2.1%)
Recovered with Sequela
32 (0.4%)

Gender Distribution

Female 4,152 (50.4%)
Male 3,923 (47.7%)
Unknown 115 (1.4%)
Mixed 42 (0.5%)

Reports by Year

Year Reports Trend
2010 27
2011 114
2012 198
2013 129
2014 233
2015 303
2016 344
2017 522
2018 539
2019 581
2020 717
2021 789
2022 787
2023 997
2024 1,246
2025 706
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Terrier - Bull - American Pit sits in the registered size-class taxonomy. Average reported weight: 27.7 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Terrier - Bull - American Pit Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Terrier - Bull - American Pit accounts for 8,232 submitted reports and currently ranks #24 by report volume within the dog population. Of those reports, 374 involved a death outcome — a 450.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 4.8 years, with an average recorded body weight of 27.7 kg (61.1 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Terrier - Bull - American Pit are Vomiting (1,543 reports), Lack of efficacy (endoparasite) - heartworm (1,016 reports), Hives (see also 'Skin') (810 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Moxidectin appears in 2,705 reports and is the single most-referenced drug, followed by Pyrantel Pamoate;Sarolaner (1,554) and Oclacitinib Maleate (1,331). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 8,199 reports with a recorded status is dominated by Ongoing (61.6% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Terrier - Bull - American Pit Adverse Event Data

With 8,232 adverse event reports, Terrier - Bull - American Pit has one of the larger report volumes in the FDA database. This typically reflects breed popularity rather than inherent health risk — more pets of a breed means more veterinary encounters and more opportunity for adverse event reporting.

The 450.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Moxidectin, appearing in 2,705 reports. This may indicate widespread use of the medication rather than a specific safety concern for Terrier - Bull - American Pit.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Terrier - Bull - American Pit?
There are 8,232 adverse event reports involving Terrier - Bull - American Pit in the FDA database, with 374 reports involving death (450.0% death rate). Terrier - Bull - American Pit ranks #24 by report volume.
What are the most common adverse reactions reported for Terrier - Bull - American Pit?
The most commonly reported adverse reactions for Terrier - Bull - American Pit are Vomiting (1,543 reports), Lack of efficacy (endoparasite) - heartworm (1,016 reports), Hives (see also 'Skin') (810 reports), Lethargy (see also Central nervous system depression in 'Neurological') (678 reports), Facial swelling (see also 'Skin') (600 reports).
What drugs are most frequently associated with Terrier - Bull - American Pit adverse events?
The drugs most frequently referenced in Terrier - Bull - American Pit adverse event reports are Moxidectin (2,705 reports), Pyrantel Pamoate;Sarolaner (1,554 reports), Oclacitinib Maleate (1,331 reports), Bedinvetmab (758 reports), Carprofen (484 reports).
What is the average age of Terrier - Bull - American Pit in adverse event reports?
The average age of Terrier - Bull - American Pit at the time of adverse event reports is 4.8 years, with an average weight of 27.7 kg (61.1 lbs).
Does a high number of adverse event reports mean Terrier - Bull - American Pit is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Bull - American Pit safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Terrier - Bull - American Pit ranks #24 by total report volume. Death rate (450.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial