The FDA adverse-event record for horse

Horse Adverse Event Insights

The FDA Center for Veterinary Medicine database holds 10,271 adverse event reports for Horse, distributed across 72 distinct breeds currently tracked in the system. Of those reports, 1,066 involved a death outcome, producing a 10.4% case-fatality rate among reported events, which reflects reporting severity bias rather than true population mortality. These figures are aggregated directly from openFDA's Animal & Veterinary Adverse Events endpoint and update as new voluntary submissions flow through pet owners, veterinarians, and drug manufacturers.

The most frequently reported clinical signs for Horse are Lack of efficacy - NOS (1,198 reports), Injection site swelling (750 reports), INEFFECTIVE, GASTRIC ULCER(S) (743 reports), Colic (703 reports), with Lack of efficacy - NOS leading the reaction traffic at 1,198 submissions. On the product side, Omeprazole is the single most-referenced drug with 1,352 reports, followed by Pergolide Mesylate (1,129), Ceftiofur Crystalline Free Acid (844), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (629). This combination surfaces which therapeutic classes generate the most adverse event chatter for this species, a useful starting point when comparing Horse reporting patterns against other companion animals in the dataset.

Of the 9,140 Horse reports with a coded outcome, Recovered/Normal accounts for the largest share at 37.4%. Annual submission volume spans 2,010 to 2,025 reports across the 16 years on file, a range that reflects evolving owner awareness, veterinary reporting habits, and new product approvals rather than stable underlying incidence. The breed-level table below breaks these patterns down further, showing how the 72 tracked horse breeds compare on volume, deaths, and average age at report. As with all FDA adverse event data, correlation is the ceiling, causation requires clinical investigation beyond what these aggregates can provide.