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Breed profile · FDA CVM July 2026 extract

Crossbred Equine/horse adverse-event record

Adverse-event filings for Crossbred Equine/horse (Horse) in the FDA Center for Veterinary Medicine openFDA extract. Browse horse breeds, reactions, and outcomes below.

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#188 of 510
by report volume (all breeds)
190
FDA CVM reports on file
7.9%
death-coded share of reports
#70 of 275
by death-coded share (≥50 reports)

How the 190 reports break down

By recorded gender -- every report on file for Crossbred Equine/horse, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 17 12.75 8.5 4.25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Crossbred Equine/horse drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Crossbred Equine/horse ranks #188 of 510 by total reports (190) and #70 of 275 by death-coded share (7.9%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#188
This breed, reports of 510
#70
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Crossbred Equine/horse has 190 reports now versus 189 in that prior snapshot: 1 more (0.5%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Crossbred Equine/horse changes

Total Reports

190

Above-median volume

Deaths Reported

15

of 190 reports

Death-coded share of reports

7.9%

Above-median death-coded share

Avg Age at Report

14.3 yr

416.7 kg avg weight

Death-Coded Outcome Share

Crossbred Equine/horse death-coded reports 7.9%
Cross-breed median

7.9% of 190 crossbred equine/horse reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Crossbred Equine/horse's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

8% 75th percentile Higher share than 75% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Crossbred Equine/horse 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 416.7 kg (918.8 lbs)

Top Reported Reactions

Lip oedema (see also 'Skin') 19
Lack of efficacy - NOS 18
Application site swelling 15
Diarrhoea 13
Anorexia 12
Facial oedema 10
Tongue oedema 9
Injection site swelling 9

Most Referenced Drugs

Pergolide Mesylate 32
Ivermectin, Praziquantel 25
Omeprazole 22
Ivermectin 14
Ivermectin + Praziquantel 14
Ponazuril 5
Hyaluronic Acid 5
Flunixin Meglumine Injectable 5

Outcome Breakdown

Recovered/Normal
56 (41.5%)
Outcome Unknown
39 (28.9%)
Ongoing
25 (18.5%)
Died
8 (5.9%)
Euthanized
7 (5.2%)

Gender Distribution

Male 108 (56.8%)
Female 66 (34.7%)
Mixed 8 (4.2%)
Unknown 8 (4.2%)

Reports by Year

Year Reports Trend
2010 21
2011 21
2012 18
2013 14
2014 7
2015 9
2016 14
2017 11
2018 8
2019 7
2020 9
2021 17
2022 6
2023 10
2024 5
2025 12
2026 1

Crossbred Equine/horse: high death-coded share in the FDA CVM extract

Signature read: Crossbred Equine/horse's 7.9% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Crossbred Equine/horse sits at #188 of 510 by report volume among all breeds and #8 of 55 among horse breeds, with 190 reports and 15 (7.9%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #70 of 275. Mean age at report: 14.3 years, average weight 416.7 kg (918.8 lbs).

Top reported signs: Lip oedema (see also 'Skin') (19), Lack of efficacy - NOS (18), Application site swelling (15). Most-referenced drug: Pergolide Mesylate (32 reports), followed by Ivermectin, Praziquantel (25) and Omeprazole (22).

Outcome coding on 135 status-recorded reports is dominated by Recovered/Normal (41.5%). Annual submissions ranged 1-2,026 across 17 years on file.

Horse Breeds With a Similar Report Volume

Showing 6 of 54 horse breeds in our dataset, ranked by closest report volume.

Tennessee Walking Horse
186 reports · 12.9% death-coded
Warmblood - Dutch
184 reports · 2.7% death-coded
Appaloosa
167 reports · 10.2% death-coded
Miniature
164 reports · 15.9% death-coded
Pony (unspecified)
151 reports · 11.9% death-coded
Morgan
145 reports · 10.3% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Crossbred Equine/horse, both outside the Horse family so the neighborhoods are not species containment (the similar-volume list above stays within species).

What to do with this horse

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Crossbred Equine/horse? ▼
There are 190 adverse event reports involving Crossbred Equine/horse in the FDA database, of which 15 were death-coded (7.9% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Crossbred Equine/horse ranks #188 of 510 by report volume among all breeds PlainBreed indexes (#8 of 55 among horse breeds).
Where does Crossbred Equine/horse sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Crossbred Equine/horse is #188 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Horse, it is #8 of 55. Among breeds with at least 50 reports, its death-coded share ranks #70 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Crossbred Equine/horse? ▼
The most commonly reported adverse reactions for Crossbred Equine/horse are Lip oedema (see also 'Skin') (19 reports), Lack of efficacy - NOS (18 reports), Application site swelling (15 reports), Diarrhoea (13 reports), Anorexia (12 reports).
What drugs are most frequently associated with Crossbred Equine/horse adverse events? ▼
The drugs most frequently referenced in Crossbred Equine/horse adverse event reports are Pergolide Mesylate (32 reports), Ivermectin, Praziquantel (25 reports), Omeprazole (22 reports), Ivermectin (14 reports), Ivermectin + Praziquantel (14 reports).
What is the average age of Crossbred Equine/horse in adverse event reports? ▼
The average age of Crossbred Equine/horse at the time of adverse event reports is 14.3 years, with an average weight of 416.7 kg (918.8 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Crossbred Equine/horse (Horse), extract as of July 2026 extract. 190 reports · 15 death-coded (7.9% of reports, not a mortality rate) · #188 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →