Cattle adverse-event record

Cattle Adverse Event Insights

The FDA Center for Veterinary Medicine database holds 15,775 adverse event reports for Cattle, distributed across 30 distinct breeds currently tracked in the system. Of those reports, 6,782 involved a death outcome, producing a 43.0% case-fatality rate among reported events, which reflects reporting severity bias rather than true population mortality. These figures are aggregated directly from openFDA's Animal & Veterinary Adverse Events endpoint and update as new voluntary submissions flow through pet owners, veterinarians, and drug manufacturers.

The most frequently reported clinical signs for Cattle are Death (5,288 reports), Lack of efficacy - NOS (2,744 reports), Lack of efficacy (bacteria) - NOS (1,719 reports), Lack of efficacy (ectoparasite) - lice (1,092 reports), with Death leading the reaction traffic at 5,288 submissions. On the product side, Monensin Sodium is the single most-referenced drug with 1,922 reports, followed by Tulathromycin (1,727), Doramectin (1,380), Ceftiofur Crystalline Free Acid (978). This combination surfaces which therapeutic classes generate the most adverse event chatter for this species, a useful starting point when comparing Cattle reporting patterns against other companion animals in the dataset.

Of the 18,088 Cattle reports with a coded outcome, Outcome Unknown accounts for the largest share at 40.1%. Annual submission volume spans 88 to 1,306 reports across the 17 years on file, a range that reflects evolving owner awareness, veterinary reporting habits, and new product approvals rather than stable underlying incidence. The breed-level table below breaks these patterns down further, showing how the 30 tracked cattle breeds compare on volume, deaths, and average age at report. As with all FDA adverse event data, correlation is the ceiling, causation requires clinical investigation beyond what these aggregates can provide.