Horse /

Thoroughbred

1,177 adverse event reports submitted to the FDA

Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your horse.
1,177
Total Reports
97
Deaths Reported
820.0%
Death Rate
11.9 yr
Avg Age at Report
Average weight at time of report: 450.4 kg (993.1 lbs)

Top Reported Reactions

Lack of efficacy - NOS 152
INEFFECTIVE, GASTRIC ULCER(S) 149
Injection site swelling 141
Fever 94
Colic 87
Injection site pain 78
Anorexia 72
Application site swelling 62
Swollen mouth 56
Death by euthanasia 54
Lethargy (see also Central nervous system depression in 'Neurological') 44
Partial lack of efficacy 41
Abnormal ultrasound finding 38
Lip oedema (see also 'Skin') 36
Death 35

Most Referenced Drugs

Omeprazole 232
Ceftiofur Crystalline Free Acid 153
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 86
Ivermectin, Praziquantel 59
Pergolide Mesylate 55
Polysulfated Glycosaminoglycan 54
Detomidine Hydrochloride 54
Sucralfate 43
Omeprazole 37% Oral Paste 42
Ceftiofur 41
Ivermectin + Praziquantel 40
Clodronate Disodium 27
Firocoxib 25
Hyaluronate Sodium 18
Ivermectin 16

Outcome Breakdown

Recovered/Normal
405 (39.3%)
Outcome Unknown
315 (30.6%)
Ongoing
199 (19.3%)
Died
49 (4.8%)
Euthanized
49 (4.8%)
Recovered with Sequela
13 (1.3%)

Gender Distribution

Male 693 (58.9%)
Female 383 (32.5%)
Unknown 53 (4.5%)
Mixed 48 (4.1%)

Reports by Year

Year Reports Trend
2010 69
2011 79
2012 69
2013 60
2014 88
2015 98
2016 72
2017 81
2018 58
2019 55
2020 86
2021 79
2022 77
2023 81
2024 69
2025 56

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #103 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.