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Breed profile · FDA CVM July 2026 extract

Thoroughbred adverse-event record

Adverse-event filings for Thoroughbred (Horse) in the FDA Center for Veterinary Medicine openFDA extract. Browse horse breeds, reactions, and outcomes below.

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#103 of 510
by report volume (all breeds)
1,222
FDA CVM reports on file
8.2%
death-coded share of reports
#66 of 275
by death-coded share (≥50 reports)

How the 1,222 reports break down

By recorded gender -- every report on file for Thoroughbred, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 89 66.75 44.5 22.25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Thoroughbred drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Thoroughbred ranks #103 of 510 by total reports (1,222) and #66 of 275 by death-coded share (8.2%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#103
This breed, reports of 510
#66
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Thoroughbred has 1,222 reports now versus 1,209 in that prior snapshot: 13 more (1.1%).

Report change
+13
Death-coded reports
+1
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Thoroughbred changes

Total Reports

1,222

High report volume

Deaths Reported

100

of 1,222 reports

Death-coded share of reports

8.2%

High death-coded share

Avg Age at Report

12.0 yr

450.7 kg avg weight

Breed Safety Scorecard

F (35/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate F
8.2%

Share of reports coded as a fatality

Euthanasia rate F
4.2%

Share of reports resulting in euthanasia

Full recovery rate B
33.8%

Share of reports coded "Recovered/Normal"

5-year trend D
+13%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Thoroughbred death-coded reports 8.2%
Cross-breed median

8.2% of 1,222 thoroughbred reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Thoroughbred's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

8% 76th percentile Higher share than 76% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Thoroughbred 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 450.7 kg (993.8 lbs)

Top Reported Reactions

Lack of efficacy - NOS 167
INEFFECTIVE, GASTRIC ULCER(S) 154
Injection site swelling 144
Fever 96
Colic 91
Injection site pain 81
Anorexia 75
Application site swelling 62
Death by euthanasia 56
Swollen mouth 56
Lethargy (see also Central nervous system depression in 'Neurological') 44
Partial lack of efficacy 43
Abnormal ultrasound finding 39
Lip oedema (see also 'Skin') 36
Anaphylaxis 36

Most Referenced Drugs

Omeprazole 252
Ceftiofur Crystalline Free Acid 160
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 86
Ivermectin, Praziquantel 59
Pergolide Mesylate 57
Polysulfated Glycosaminoglycan 57
Detomidine Hydrochloride 55
Sucralfate 54
Omeprazole 37% Oral Paste 42
Ivermectin + Praziquantel 42
Ceftiofur 41
Firocoxib 28
Clodronate Disodium 27
Hyaluronate Sodium 19
Pentosan Polysulfate Sodium 17

Outcome Breakdown

Recovered/Normal
413 (38.4%)
Outcome Unknown
338 (31.4%)
Ongoing
210 (19.5%)
Euthanized
51 (4.7%)
Died
50 (4.7%)
Recovered with Sequela
13 (1.2%)

Gender Distribution

Male 722 (59.1%)
Female 398 (32.6%)
Unknown 54 (4.4%)
Mixed 48 (3.9%)

Reports by Year

Year Reports Trend
2010 69
2011 79
2012 69
2013 60
2014 88
2015 98
2016 72
2017 81
2018 58
2019 55
2020 86
2021 79
2022 77
2023 81
2024 70
2025 89
2026 11

Thoroughbred: high death-coded share in the FDA CVM extract

Signature read: 1,222 reports place Thoroughbred in the upper third of breed filing volume (#103 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Thoroughbred sits at #103 of 510 by report volume among all breeds and #3 of 55 among horse breeds, with 1,222 reports and 100 (8.2%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #66 of 275. Mean age at report: 12.0 years, average weight 450.7 kg (993.8 lbs).

Top reported signs: Lack of efficacy - NOS (167), INEFFECTIVE, GASTRIC ULCER(S) (154), Injection site swelling (144). Most-referenced drug: Omeprazole (252 reports), followed by Ceftiofur Crystalline Free Acid (160) and Ivermectin(1.55%)/Praziquantel(7.75%) Paste (86).

Outcome coding on 1,075 status-recorded reports is dominated by Recovered/Normal (38.4%). Annual submissions ranged 11-2,026 across 17 years on file.

Horse Breeds With a Similar Report Volume

Showing 6 of 54 horse breeds in our dataset, ranked by closest report volume.

Warmblood (unspecified)
541 reports · 7.0% death-coded
Arab
467 reports · 9.6% death-coded
Paint
386 reports · 13.7% death-coded
Horse (other)
296 reports · 9.8% death-coded
Crossbred Equine/horse
190 reports · 7.9% death-coded
Tennessee Walking Horse
186 reports · 12.9% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Thoroughbred drawn from openFDA outside the Horse family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (8.2% death-coded here).

Rottweiler 8.2% · Dog Dachshund - Standard Smooth-haired 8.2% · Dog Siamese 8.1% · Cat Scottish Fold Shorthair 8.3% · Cat

What to do with this horse

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Thoroughbred? ▼
There are 1,222 adverse event reports involving Thoroughbred in the FDA database, of which 100 were death-coded (8.2% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Thoroughbred ranks #103 of 510 by report volume among all breeds PlainBreed indexes (#3 of 55 among horse breeds).
Where does Thoroughbred sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Thoroughbred is #103 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Horse, it is #3 of 55. Among breeds with at least 50 reports, its death-coded share ranks #66 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Thoroughbred? ▼
The most commonly reported adverse reactions for Thoroughbred are Lack of efficacy - NOS (167 reports), INEFFECTIVE, GASTRIC ULCER(S) (154 reports), Injection site swelling (144 reports), Fever (96 reports), Colic (91 reports).
What drugs are most frequently associated with Thoroughbred adverse events? ▼
The drugs most frequently referenced in Thoroughbred adverse event reports are Omeprazole (252 reports), Ceftiofur Crystalline Free Acid (160 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (86 reports), Ivermectin, Praziquantel (59 reports), Pergolide Mesylate (57 reports).
What is the average age of Thoroughbred in adverse event reports? ▼
The average age of Thoroughbred at the time of adverse event reports is 12.0 years, with an average weight of 450.7 kg (993.8 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Thoroughbred (Horse), extract as of July 2026 extract. 1,222 reports · 100 death-coded (8.2% of reports, not a mortality rate) · #103 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →