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2026 FDA CVM data 621 reports on file official source

Himalayan — FDA Adverse Event Profile

Adverse-event records and label data for Himalayan (Cat), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 48 36 24 12 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Himalayan drawn from FDA CVM filings.

Himalayan (Cat) has 621 FDA adverse event reports on record, with 67 deaths reported (1080.0% death rate) — ranking #126 by report volume. The most frequently reported reaction is Vomiting (94 cases). The top associated drug is Spinosad. Average age at report: 8.6 years.

Total Reports

621

FDA CVM filings

Deaths Reported

67

of 621 reports

Death Rate

1080.0%

death-coded share

Avg Age at Report

8.6 yr

4.2 kg avg weight

Death-Coded Outcome Share

Himalayan death-coded reports 100.0%
Database median

1080.0% of 621 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 4.2 kg (9.3 lbs)

Top Reported Reactions

Vomiting 94
Lethargy (see also Central nervous system depression in 'Neurological') 72
Lack of efficacy (ectoparasite) - flea 65
Anorexia 55
Emesis 44
Diarrhoea 41
Weight loss 39
Death by euthanasia 29
Behavioural disorder NOS 29
Panting 28
Hyperactivity 26
Death 26
Not eating 26
Lack of efficacy - NOS 25
Ataxia 24

Most Referenced Drugs

Spinosad 98
Selamectin 77
Nitenpyram 58
Fluralaner Spot-On Solution 45
Imidacloprid + Moxidectin 42
Cefovecin 33
Frunevetmab 28
Selamectin;Sarolaner 21
Cefovecin Sodium 18
Maropitant Citrate 18
Meloxicam 17
Mirtazapine 16
Buprenorphine 15
Cyclosporine 12
Methylprednisolone Acetate 11

Outcome Breakdown

Recovered/Normal
183 (33.0%)
Outcome Unknown
150 (27.1%)
Ongoing
145 (26.2%)
Died
38 (6.9%)
Euthanized
29 (5.2%)
Recovered with Sequela
9 (1.6%)

Gender Distribution

Male 305 (49.1%)
Female 302 (48.6%)
Unknown 12 (1.9%)
Mixed 2 (0.3%)

Reports by Year

Year Reports Trend
2010 49
2011 27
2012 40
2013 74
2014 51
2015 42
2016 44
2017 46
2018 33
2019 34
2020 19
2021 27
2022 25
2023 48
2024 38
2025 24
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Himalayan sits in the registered size-class taxonomy. Average reported weight: 4.2 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Himalayan Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Himalayan accounts for 621 submitted reports and currently ranks #126 by report volume within the cat population. Of those reports, 67 involved a death outcome — a 1080.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 8.6 years, with an average recorded body weight of 4.2 kg (9.3 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Himalayan are Vomiting (94 reports), Lethargy (see also Central nervous system depression in 'Neurological') (72 reports), Lack of efficacy (ectoparasite) - flea (65 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Spinosad appears in 98 reports and is the single most-referenced drug, followed by Selamectin (77) and Nitenpyram (58). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same cat species.

Outcome coding on the 554 reports with a recorded status is dominated by Recovered/Normal (33.0% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual cat.

Understanding Himalayan Adverse Event Data

Himalayan has a moderate volume of adverse event reports (621). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 1080.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Spinosad, appearing in 98 reports. This may indicate widespread use of the medication rather than a specific safety concern for Himalayan.

Other Cat Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Himalayan?
There are 621 adverse event reports involving Himalayan in the FDA database, with 67 reports involving death (1080.0% death rate). Himalayan ranks #126 by report volume.
What are the most common adverse reactions reported for Himalayan?
The most commonly reported adverse reactions for Himalayan are Vomiting (94 reports), Lethargy (see also Central nervous system depression in 'Neurological') (72 reports), Lack of efficacy (ectoparasite) - flea (65 reports), Anorexia (55 reports), Emesis (44 reports).
What drugs are most frequently associated with Himalayan adverse events?
The drugs most frequently referenced in Himalayan adverse event reports are Spinosad (98 reports), Selamectin (77 reports), Nitenpyram (58 reports), Fluralaner Spot-On Solution (45 reports), Imidacloprid + Moxidectin (42 reports).
What is the average age of Himalayan in adverse event reports?
The average age of Himalayan at the time of adverse event reports is 8.6 years, with an average weight of 4.2 kg (9.3 lbs).
Does a high number of adverse event reports mean Himalayan is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Himalayan safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Himalayan ranks #126 by total report volume. Death rate (1080.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial