Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
982
Total Reports
88
Deaths Reported
900.0%
Death Rate
6.6 yr
Avg Age at Report
Average weight at time of report: 4.8 kg (10.6 lbs)
Top Reported Reactions
Vomiting 126
Lethargy (see also Central nervous system depression in 'Neurological') 110
Lack of efficacy (ectoparasite) - flea 88
Diarrhoea 74
Behavioural disorder NOS 72
Anorexia 64
Weight loss 53
Not eating 50
Lethargy (see also Central nervous system depression in Neurological) 46
Application site hair loss 45
Hypersalivation 44
Death by euthanasia 44
Ataxia 44
Application site alopecia 43
Panting 39
Most Referenced Drugs
Selamectin 129
Spinosad 82
Nitenpyram 80
Selamectin;Sarolaner 77
Buprenorphine 72
Frunevetmab 71
Fluralaner Spot-On Solution 69
Cefovecin 57
Imidacloprid + Moxidectin 54
Maropitant Citrate 46
Robenacoxib 33
Cefovecin Sodium 27
Mirtazapine 26
Eprinomectin + Esafoxolaner + Praziquantel 25
Meloxicam 23
Outcome Breakdown
Ongoing
326 (35.2%)
Recovered/Normal
254 (27.4%)
Outcome Unknown
250 (27.0%)
Died
47 (5.1%)
Euthanized
41 (4.4%)
Recovered with Sequela
8 (0.9%)
Gender Distribution
Male 516 (52.5%)
Female 437 (44.5%)
Unknown 19 (1.9%)
Mixed 10 (1.0%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 31 | |
| 2011 | 32 | |
| 2012 | 33 | |
| 2013 | 45 | |
| 2014 | 66 | |
| 2015 | 44 | |
| 2016 | 43 | |
| 2017 | 64 | |
| 2018 | 70 | |
| 2019 | 62 | |
| 2020 | 47 | |
| 2021 | 54 | |
| 2022 | 72 | |
| 2023 | 125 | |
| 2024 | 121 | |
| 2025 | 73 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #111 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.