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FDA CVM · 2025 release 982 reports on file

Ragdoll - FDA Adverse Event Profile

Adverse-event records for Ragdoll (Cat) from the FDA Center for Veterinary Medicine.

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Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 125 93.75 62.5 31.25 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Ragdoll drawn from FDA CVM filings.

Data updated June 2026

The record at a glance

With 982 reports on file, Ragdoll sits at #111 among cat breeds by volume; death-coded share is 9.0% (88 reports).

#111
most-reported cat breed
9.0%
death-coded report share
126
Vomiting - top reaction
6.6 yr
average age at report

Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.

Total Reports

982

FDA CVM filings

Deaths Reported

88

of 982 reports

Death Rate

9.0%

death-coded share

Avg Age at Report

6.6 yr

4.8 kg avg weight

Death-Coded Outcome Share

Ragdoll death-coded reports 9.0%
Cross-breed median

9.0% of 982 ragdoll reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 4.8 kg (10.6 lbs)

Top Reported Reactions

Vomiting 126
Lethargy (see also Central nervous system depression in 'Neurological') 110
Lack of efficacy (ectoparasite) - flea 88
Diarrhoea 74
Behavioural disorder NOS 72
Anorexia 64
Weight loss 53
Not eating 50

Most Referenced Drugs

Selamectin 129
Spinosad 82
Nitenpyram 80
Selamectin;Sarolaner 77
Buprenorphine 72
Frunevetmab 71
Fluralaner Spot-On Solution 69
Cefovecin 57

Outcome Breakdown

Ongoing
326 (35.2%)
Recovered/Normal
254 (27.4%)
Outcome Unknown
250 (27.0%)
Died
47 (5.1%)
Euthanized
41 (4.4%)
Recovered with Sequela
8 (0.9%)

Gender Distribution

Male 516 (52.5%)
Female 437 (44.5%)
Unknown 19 (1.9%)
Mixed 10 (1.0%)

Reports by Year

Year Reports Trend
2010 31
2011 32
2012 33
2013 45
2014 66
2015 44
2016 43
2017 64
2018 70
2019 62
2020 47
2021 54
2022 72
2023 125
2024 121
2025 73

Ragdoll Pet Health Insights

Ragdoll accounts for 982 FDA adverse event reports, ranking #111 by volume among cat breeds, with 88 reports (9.0%) coded as a death outcome. Mean age at report: 6.6 years, average weight 4.8 kg (10.6 lbs).

Top reported signs: Vomiting (126), Lethargy (see also Central nervous system depression in 'Neurological') (110), Lack of efficacy (ectoparasite) - flea (88). Most-referenced drug: Selamectin (129 reports), followed by Spinosad (82) and Nitenpyram (80).

Outcome coding on 926 status-recorded reports is dominated by Ongoing (35.2%). Annual submissions ranged 2,010-2,025 across 16 years on file.

Cat Breeds With a Similar Report Volume

Frequently Asked Questions

How many FDA adverse event reports involve Ragdoll?
There are 982 adverse event reports involving Ragdoll in the FDA database, with 88 reports involving death (9.0% death rate). Ragdoll ranks #111 by report volume.
What are the most common adverse reactions reported for Ragdoll?
The most commonly reported adverse reactions for Ragdoll are Vomiting (126 reports), Lethargy (see also Central nervous system depression in 'Neurological') (110 reports), Lack of efficacy (ectoparasite) - flea (88 reports), Diarrhoea (74 reports), Behavioural disorder NOS (72 reports).
What drugs are most frequently associated with Ragdoll adverse events?
The drugs most frequently referenced in Ragdoll adverse event reports are Selamectin (129 reports), Spinosad (82 reports), Nitenpyram (80 reports), Selamectin;Sarolaner (77 reports), Buprenorphine (72 reports).
What is the average age of Ragdoll in adverse event reports?
The average age of Ragdoll at the time of adverse event reports is 6.6 years, with an average weight of 4.8 kg (10.6 lbs).
Does a high number of adverse event reports mean Ragdoll is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Ragdoll safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.