Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
122
Total Reports
11
Deaths Reported
900.0%
Death Rate
5.7 yr
Avg Age at Report
Average weight at time of report: 30.2 kg (66.6 lbs)
Top Reported Reactions
Vomiting 23
Diarrhoea 14
Lack of efficacy (bacteria) - Borrelia 12
Lethargy (see also Central nervous system depression in Neurological) 12
Lack of efficacy (ectoparasite) - flea 12
Polyuria 9
Polydipsia 9
Decreased appetite 9
Seizure NOS 7
Death by euthanasia 7
Lack of efficacy (endoparasite) - hookworm 6
Weight loss 6
Lack of efficacy - NOS 6
Not himself/herself 5
Anorexia 5
Most Referenced Drugs
Bedinvetmab 32
Pyrantel Pamoate;Sarolaner 20
Afoxolaner 14
Maropitant Citrate 13
Gabapentin 9
Fluralaner 13.64% 12-Week Chew 9
Milbemycin Oxime + Praziquantel 8
Moxidectin 7
Carprofen 6
Ivermectin + Pyrantel As Pamoate Salt 6
Oclacitinib Maleate 6
Galliprant 5
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 4
Ondansetron 4
Entyce 4
Outcome Breakdown
Ongoing
55 (45.1%)
Outcome Unknown
29 (23.8%)
Recovered/Normal
27 (22.1%)
Euthanized
8 (6.6%)
Died
3 (2.5%)
Gender Distribution
Female 63 (51.6%)
Male 59 (48.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2017 | 1 | |
| 2021 | 1 | |
| 2022 | 1 | |
| 2023 | 5 | |
| 2024 | 75 | |
| 2025 | 39 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #221 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.