Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
646
Total Reports
31
Deaths Reported
480.0%
Death Rate
5.9 yr
Avg Age at Report
Average weight at time of report: 4.8 kg (10.6 lbs)
Top Reported Reactions
Vomiting 102
Application site hair loss 83
Lethargy (see also Central nervous system depression in 'Neurological') 75
Application site alopecia 68
Diarrhoea 50
Anorexia 44
Behavioural disorder NOS 31
Weight loss 31
Ataxia 29
Not eating 29
Lack of efficacy (ectoparasite) - flea 28
Lethargy (see also Central nervous system depression in Neurological) 28
Vocalisation 25
Application site scab 25
Emesis 25
Most Referenced Drugs
Selamectin 125
Fluralaner Spot-On Solution 65
Selamectin;Sarolaner 50
Spinosad 49
Cefovecin 40
Frunevetmab 40
Imidacloprid + Moxidectin 36
Emodepside + Praziquantel 29
Maropitant Citrate 26
Robenacoxib 24
Buprenorphine 21
Cyclosporine 20
Nitenpyram 19
Mirtazapine 15
Fluralaner/Moxidectin Spot-On 15
Outcome Breakdown
Outcome Unknown
221 (36.3%)
Ongoing
204 (33.6%)
Recovered/Normal
147 (24.2%)
Died
17 (2.8%)
Euthanized
14 (2.3%)
Recovered with Sequela
5 (0.8%)
Gender Distribution
Male 363 (56.2%)
Female 262 (40.6%)
Unknown 15 (2.3%)
Mixed 6 (0.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 18 | |
| 2011 | 23 | |
| 2012 | 23 | |
| 2013 | 32 | |
| 2014 | 40 | |
| 2015 | 41 | |
| 2016 | 40 | |
| 2017 | 35 | |
| 2018 | 43 | |
| 2019 | 67 | |
| 2020 | 33 | |
| 2021 | 46 | |
| 2022 | 37 | |
| 2023 | 46 | |
| 2024 | 84 | |
| 2025 | 38 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #124 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.