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Breed profile · FDA CVM July 2026 extract

Persian adverse-event record

Adverse-event filings for Persian (Cat) in the FDA Center for Veterinary Medicine openFDA extract. Browse cat breeds, reactions, and outcomes below.

#104 of 510
by report volume (all breeds)
1,215
FDA CVM reports on file
9.7%
death-coded share of reports
#52 of 275
by death-coded share (≥50 reports)

How the 1,215 reports break down

By recorded gender -- every report on file for Persian, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 101 75.75 50.5 25.25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Persian drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Persian ranks #104 of 510 by total reports (1,215) and #52 of 275 by death-coded share (9.7%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#104
This breed, reports of 510
#52
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Persian has 1,215 reports now versus 1,195 in that prior snapshot: 20 more (1.7%).

Report change
+20
Death-coded reports
+1
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Persian changes

Total Reports

1,215

High report volume

Deaths Reported

118

of 1,215 reports

Death-coded share of reports

9.7%

High death-coded share

Avg Age at Report

7.3 yr

3.8 kg avg weight

Breed Safety Scorecard

F (18/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate F
9.7%

Share of reports coded as a fatality

Euthanasia rate F
3.7%

Share of reports resulting in euthanasia

Full recovery rate F
25.9%

Share of reports coded "Recovered/Normal"

5-year trend F
+102%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Persian death-coded reports 9.7%
Cross-breed median

9.7% of 1,215 persian reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Persian's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

10% 81st percentile Higher share than 81% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Persian 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 3.8 kg (8.4 lbs)

Top Reported Reactions

Vomiting 166
Lethargy (see also Central nervous system depression in 'Neurological') 161
Lack of efficacy (ectoparasite) - flea 143
Anorexia 108
Diarrhoea 87
Emesis 78
Behavioural disorder NOS 77
Lack of efficacy - NOS 68
Ataxia 66
Death 62
Weight loss 55
Not eating 53
Vocalisation 50
Death by euthanasia 49
Panting 46

Most Referenced Drugs

Spinosad 193
Selamectin 159
Nitenpyram 115
Fluralaner Spot-On Solution 101
Cefovecin 85
Buprenorphine 65
Frunevetmab 62
Imidacloprid + Moxidectin 59
Selamectin;Sarolaner 55
Maropitant Citrate 40
Isoflurane 35
Cefovecin Sodium 29
Robenacoxib 29
Mirtazapine 24
Fluralaner/Moxidectin Spot-On 23

Outcome Breakdown

Ongoing
335 (30.1%)
Outcome Unknown
328 (29.4%)
Recovered/Normal
315 (28.3%)
Died
73 (6.6%)
Euthanized
45 (4.0%)
Recovered with Sequela
18 (1.6%)

Gender Distribution

Male 610 (50.2%)
Female 561 (46.2%)
Unknown 34 (2.8%)
Mixed 10 (0.8%)

Reports by Year

Year Reports Trend
2010 59
2011 56
2012 74
2013 111
2014 83
2015 64
2016 62
2017 94
2018 88
2019 80
2020 64
2021 41
2022 50
2023 101
2024 88
2025 83
2026 17

Persian: high death-coded share in the FDA CVM extract

Signature read: Persian's 9.7% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Persian sits at #104 of 510 by report volume among all breeds and #9 of 55 among cat breeds, with 1,215 reports and 118 (9.7%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #52 of 275. Mean age at report: 7.3 years, average weight 3.8 kg (8.4 lbs).

Top reported signs: Vomiting (166), Lethargy (see also Central nervous system depression in 'Neurological') (161), Lack of efficacy (ectoparasite) - flea (143). Most-referenced drug: Spinosad (193 reports), followed by Selamectin (159) and Nitenpyram (115).

Outcome coding on 1,114 status-recorded reports is dominated by Ongoing (30.1%). Annual submissions ranged 17-2,026 across 17 years on file.

Cat Breeds With a Similar Report Volume

Showing 6 of 54 cat breeds in our dataset, ranked by closest report volume.

Nationwide breeds with similar profiles

High-volume peer sets for Persian drawn from openFDA outside the Cat family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (9.7% death-coded here).

Similar average weight

Nearest other-species breeds by reported average weight (3.8 kg here).

What to do with this cat

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Persian?
There are 1,215 adverse event reports involving Persian in the FDA database, of which 118 were death-coded (9.7% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Persian ranks #104 of 510 by report volume among all breeds PlainBreed indexes (#9 of 55 among cat breeds).
Where does Persian sit among other breeds in PlainBreed's corpus?
According to FDA CVM report volume, Persian is #104 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Cat, it is #9 of 55. Among breeds with at least 50 reports, its death-coded share ranks #52 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Persian?
The most commonly reported adverse reactions for Persian are Vomiting (166 reports), Lethargy (see also Central nervous system depression in 'Neurological') (161 reports), Lack of efficacy (ectoparasite) - flea (143 reports), Anorexia (108 reports), Diarrhoea (87 reports).
What drugs are most frequently associated with Persian adverse events?
The drugs most frequently referenced in Persian adverse event reports are Spinosad (193 reports), Selamectin (159 reports), Nitenpyram (115 reports), Fluralaner Spot-On Solution (101 reports), Cefovecin (85 reports).
What is the average age of Persian in adverse event reports?
The average age of Persian at the time of adverse event reports is 7.3 years, with an average weight of 3.8 kg (8.4 lbs).

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Persian (Cat), extract as of July 2026 extract. 1,215 reports · 118 death-coded (9.7% of reports, not a mortality rate) · #104 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →