Total Reports
1,162
FDA CVM filings
Cat /
FDA CVM · 2025 release 1,162 reports on file
Persian - FDA Adverse Event Profile
Adverse-event records for Persian (Cat) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Persian's FDA record: #104 most-reported cat breed, 1,162 total reports, 9.6% death-coded (112 reports).
- #104
- most-reported cat breed
- 9.6%
- death-coded report share
- 161
- Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
- 7.2 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
112
of 1,162 reports
Death Rate
9.6%
death-coded share
Avg Age at Report
7.2 yr
3.8 kg avg weight
Death-Coded Outcome Share
Persian death-coded reports 9.6%
Cross-breed median
9.6% of 1,162 persian reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 3.8 kg (8.4 lbs)
Top Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 161
Vomiting 160
Lack of efficacy (ectoparasite) - flea 132
Anorexia 107
Diarrhoea 80
Emesis 78
Behavioural disorder NOS 74
Lack of efficacy - NOS 65
Ataxia 64
Death 57
Weight loss 53
Not eating 52
Vocalisation 49
Death by euthanasia 48
Decreased appetite 45
Most Referenced Drugs
Spinosad 193
Selamectin 157
Nitenpyram 113
Fluralaner Spot-On Solution 94
Cefovecin 82
Imidacloprid + Moxidectin 58
Buprenorphine 57
Frunevetmab 52
Selamectin;Sarolaner 49
Maropitant Citrate 35
Isoflurane 30
Robenacoxib 29
Cefovecin Sodium 28
Mirtazapine 22
Fluralaner/Moxidectin Spot-On 21
Outcome Breakdown
Outcome Unknown
313 (29.5%)
Ongoing
312 (29.4%)
Recovered/Normal
306 (28.8%)
Died
68 (6.4%)
Euthanized
44 (4.1%)
Recovered with Sequela
18 (1.7%)
Gender Distribution
Male 579 (49.8%)
Female 543 (46.7%)
Unknown 30 (2.6%)
Mixed 10 (0.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 59 | |
| 2011 | 56 | |
| 2012 | 74 | |
| 2013 | 111 | |
| 2014 | 83 | |
| 2015 | 64 | |
| 2016 | 62 | |
| 2017 | 94 | |
| 2018 | 88 | |
| 2019 | 80 | |
| 2020 | 64 | |
| 2021 | 41 | |
| 2022 | 50 | |
| 2023 | 101 | |
| 2024 | 88 | |
| 2025 | 47 | |
Persian Pet Health Insights
Persian accounts for 1,162 FDA adverse event reports, ranking #104 by volume among cat breeds, with 112 reports (9.6%) coded as a death outcome. Mean age at report: 7.2 years, average weight 3.8 kg (8.4 lbs).
Top reported signs: Lethargy (see also Central nervous system depression in 'Neurological') (161), Vomiting (160), Lack of efficacy (ectoparasite) - flea (132). Most-referenced drug: Spinosad (193 reports), followed by Selamectin (157) and Nitenpyram (113).
Outcome coding on 1,061 status-recorded reports is dominated by Outcome Unknown (29.5%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Cat Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Persian? ▼
There are 1,162 adverse event reports involving Persian in the FDA database, with 112 reports involving death (9.6% death rate). Persian ranks #104 by report volume.
What are the most common adverse reactions reported for Persian? ▼
The most commonly reported adverse reactions for Persian are Lethargy (see also Central nervous system depression in 'Neurological') (161 reports), Vomiting (160 reports), Lack of efficacy (ectoparasite) - flea (132 reports), Anorexia (107 reports), Diarrhoea (80 reports).
What drugs are most frequently associated with Persian adverse events? ▼
The drugs most frequently referenced in Persian adverse event reports are Spinosad (193 reports), Selamectin (157 reports), Nitenpyram (113 reports), Fluralaner Spot-On Solution (94 reports), Cefovecin (82 reports).
What is the average age of Persian in adverse event reports? ▼
The average age of Persian at the time of adverse event reports is 7.2 years, with an average weight of 3.8 kg (8.4 lbs).
Does a high number of adverse event reports mean Persian is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Persian safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.