Cat /

American Shorthair

411 adverse event reports submitted to the FDA

Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
411
Total Reports
31
Deaths Reported
750.0%
Death Rate
7.1 yr
Avg Age at Report
Average weight at time of report: 5.2 kg (11.5 lbs)

Top Reported Reactions

Vomiting 64
Lack of efficacy (ectoparasite) - flea 42
Emesis 30
Application site hair loss 29
Behavioural disorder NOS 28
Lethargy (see also Central nervous system depression in 'Neurological') 27
Application site alopecia 24
Hypersalivation 23
Lack of efficacy - NOS 22
Anorexia 20
Vocalisation 18
Diarrhoea 18
Weight loss 18
Not eating 18
Hyperactivity 17

Most Referenced Drugs

Spinosad 59
Selamectin 49
Fluralaner Spot-On Solution 43
Imidacloprid + Moxidectin 22
Buprenorphine 20
Nitenpyram 19
Fluralaner/Moxidectin Spot-On 18
Porcine Insulin 17
Robenacoxib 17
Emodepside + Praziquantel 15
Cyclosporine 14
Bexagliflozin 14
Eprinomectin + Esafoxolaner + Praziquantel 14
Cefovecin 10
Maropitant Citrate 10

Outcome Breakdown

Outcome Unknown
120 (32.3%)
Recovered/Normal
111 (29.9%)
Ongoing
105 (28.3%)
Died
19 (5.1%)
Euthanized
12 (3.2%)
Recovered with Sequela
4 (1.1%)

Gender Distribution

Male 229 (55.7%)
Female 174 (42.3%)
Unknown 4 (1.0%)
Mixed 4 (1.0%)

Reports by Year

Year Reports Trend
2010 37
2011 3
2012 24
2013 27
2014 33
2015 24
2016 9
2017 16
2018 20
2019 24
2020 12
2021 12
2022 11
2023 33
2024 77
2025 49

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #151 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.