Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
179
Total Reports
16
Deaths Reported
890.0%
Death Rate
5.5 yr
Avg Age at Report
Average weight at time of report: 23.5 kg (51.8 lbs)
Top Reported Reactions
Lack of efficacy (endoparasite) - heartworm 28
Lack of efficacy (ectoparasite) - tick NOS 20
Emesis 15
Vomiting 15
Lack of efficacy (endoparasite) - hookworm 12
Lethargy (see also Central nervous system depression in 'Neurological') 12
Diarrhoea 9
Death 8
Digestive tract disorder NOS 8
Lack of efficacy - NOS 8
Behavioural disorder NOS 7
Seizure NOS 7
Lack of efficacy (endoparasite) - whipworm 7
INEFFECTIVE, HEARTWORM LARVAE 7
Weight loss 6
Most Referenced Drugs
Milbemycin Oxime + Spinosad 50
Milbemycin Oxime + Praziquantel 40
Fluralaner Chew Tablets 18
Fluralaner 17
Ivermectin + Pyrantel As Pamoate Salt 16
Desoxycorticosterone Pivalate 8
Prednisone 7
Fluralaner 13.64% 12-Week Chew 7
Milbemycin Oxime 5
Milbemycin/Lufenuron/Pzq Chew 5
Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg 4
Ivermectin + Pyrantel 4
Afoxolaner 3
Fenbendazol Granules 3
Deracoxib 3
Outcome Breakdown
Outcome Unknown
80 (44.4%)
Recovered/Normal
43 (23.9%)
Ongoing
31 (17.2%)
Died
10 (5.6%)
Recovered with Sequela
10 (5.6%)
Euthanized
6 (3.3%)
Gender Distribution
Female 95 (53.1%)
Male 80 (44.7%)
Unknown 4 (2.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 1 | |
| 2012 | 10 | |
| 2013 | 16 | |
| 2014 | 22 | |
| 2015 | 12 | |
| 2016 | 17 | |
| 2017 | 10 | |
| 2018 | 22 | |
| 2019 | 17 | |
| 2020 | 15 | |
| 2021 | 14 | |
| 2022 | 12 | |
| 2023 | 11 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #190 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.