Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
585
Total Reports
42
Deaths Reported
720.0%
Death Rate
7.7 yr
Avg Age at Report
Average weight at time of report: 5.1 kg (11.2 lbs)
Top Reported Reactions
Vomiting 85
Application site hair loss 58
Lack of efficacy (ectoparasite) - flea 57
Lethargy (see also Central nervous system depression in 'Neurological') 57
Application site alopecia 45
Behavioural disorder NOS 42
Anorexia 38
Diarrhoea 33
Vocalisation 32
Weight loss 31
Lethargy (see also Central nervous system depression in Neurological) 29
Emesis 27
Pruritus 26
Ataxia 22
Hypersalivation 22
Most Referenced Drugs
Selamectin 75
Spinosad 61
Fluralaner Spot-On Solution 54
Selamectin;Sarolaner 53
Nitenpyram 42
Frunevetmab 39
Imidacloprid + Moxidectin 32
Cefovecin 29
Emodepside + Praziquantel 20
Buprenorphine 19
Maropitant Citrate 18
Robenacoxib 16
Praziquantel 14
Fluralaner/Moxidectin Spot-On 14
Eprinomectin + Esafoxolaner + Praziquantel 14
Outcome Breakdown
Outcome Unknown
190 (34.4%)
Ongoing
174 (31.5%)
Recovered/Normal
144 (26.0%)
Died
23 (4.2%)
Euthanized
19 (3.4%)
Recovered with Sequela
3 (0.5%)
Gender Distribution
Male 310 (53.0%)
Female 266 (45.5%)
Unknown 7 (1.2%)
Mixed 2 (0.3%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 14 | |
| 2011 | 14 | |
| 2012 | 24 | |
| 2013 | 17 | |
| 2014 | 21 | |
| 2015 | 32 | |
| 2016 | 38 | |
| 2017 | 36 | |
| 2018 | 47 | |
| 2019 | 43 | |
| 2020 | 40 | |
| 2021 | 48 | |
| 2022 | 24 | |
| 2023 | 57 | |
| 2024 | 88 | |
| 2025 | 42 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #129 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.