Total Reports
585
FDA CVM filings
Cat /
2026 FDA CVM data 585 reports on file official source
Russian — FDA Adverse Event Profile
Adverse-event records and label data for Russian (Cat), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.
Russian (Cat) has 585 FDA adverse event reports on record, with 42 deaths reported (720.0% death rate) — ranking #129 by report volume. The most frequently reported reaction is Vomiting (85 cases). The top associated drug is Selamectin. Average age at report: 7.7 years.
Deaths Reported
42
of 585 reports
Death Rate
720.0%
death-coded share
Avg Age at Report
7.7 yr
5.1 kg avg weight
Death-Coded Outcome Share
Russian death-coded reports 100.0%
Database median
720.0% of 585 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 5.1 kg (11.2 lbs)
Top Reported Reactions
Vomiting 85
Application site hair loss 58
Lack of efficacy (ectoparasite) - flea 57
Lethargy (see also Central nervous system depression in 'Neurological') 57
Application site alopecia 45
Behavioural disorder NOS 42
Anorexia 38
Diarrhoea 33
Vocalisation 32
Weight loss 31
Lethargy (see also Central nervous system depression in Neurological) 29
Emesis 27
Pruritus 26
Ataxia 22
Hypersalivation 22
Most Referenced Drugs
Selamectin 75
Spinosad 61
Fluralaner Spot-On Solution 54
Selamectin;Sarolaner 53
Nitenpyram 42
Frunevetmab 39
Imidacloprid + Moxidectin 32
Cefovecin 29
Emodepside + Praziquantel 20
Buprenorphine 19
Maropitant Citrate 18
Robenacoxib 16
Praziquantel 14
Fluralaner/Moxidectin Spot-On 14
Eprinomectin + Esafoxolaner + Praziquantel 14
Outcome Breakdown
Outcome Unknown
190 (34.4%)
Ongoing
174 (31.5%)
Recovered/Normal
144 (26.0%)
Died
23 (4.2%)
Euthanized
19 (3.4%)
Recovered with Sequela
3 (0.5%)
Gender Distribution
Male 310 (53.0%)
Female 266 (45.5%)
Unknown 7 (1.2%)
Mixed 2 (0.3%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 14 | |
| 2011 | 14 | |
| 2012 | 24 | |
| 2013 | 17 | |
| 2014 | 21 | |
| 2015 | 32 | |
| 2016 | 38 | |
| 2017 | 36 | |
| 2018 | 47 | |
| 2019 | 43 | |
| 2020 | 40 | |
| 2021 | 48 | |
| 2022 | 24 | |
| 2023 | 57 | |
| 2024 | 88 | |
| 2025 | 42 | |
Russian Pet Health Insights
Across the FDA Center for Veterinary Medicine adverse event database, Russian accounts for 585 submitted reports and currently ranks #129 by report volume within the cat population. Of those reports, 42 involved a death outcome — a 720.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 7.7 years, with an average recorded body weight of 5.1 kg (11.2 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.
The most frequently reported clinical signs for Russian are Vomiting (85 reports), Application site hair loss (58 reports), Lack of efficacy (ectoparasite) - flea (57 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Selamectin appears in 75 reports and is the single most-referenced drug, followed by Spinosad (61) and Fluralaner Spot-On Solution (54). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same cat species.
Outcome coding on the 553 reports with a recorded status is dominated by Outcome Unknown (34.4% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual cat.
Understanding Russian Adverse Event Data
Russian has a moderate volume of adverse event reports (585). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.
The 720.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.
The most frequently referenced drug in adverse reports is Selamectin, appearing in 75 reports. This may indicate widespread use of the medication rather than a specific safety concern for Russian.
Other Cat Breeds
Domestic Shorthair
61,410 reports · 720.0% death rate
Cat (unknown)
12,555 reports · 930.0% death rate
Domestic Longhair
9,078 reports · 690.0% death rate
Domestic (unspecified)
7,559 reports · 1340.0% death rate
Domestic Mediumhair
6,057 reports · 760.0% death rate
Cat (other)
4,619 reports · 970.0% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Russian? ▼
There are 585 adverse event reports involving Russian in the FDA database, with 42 reports involving death (720.0% death rate). Russian ranks #129 by report volume.
What are the most common adverse reactions reported for Russian? ▼
The most commonly reported adverse reactions for Russian are Vomiting (85 reports), Application site hair loss (58 reports), Lack of efficacy (ectoparasite) - flea (57 reports), Lethargy (see also Central nervous system depression in 'Neurological') (57 reports), Application site alopecia (45 reports).
What drugs are most frequently associated with Russian adverse events? ▼
The drugs most frequently referenced in Russian adverse event reports are Selamectin (75 reports), Spinosad (61 reports), Fluralaner Spot-On Solution (54 reports), Selamectin;Sarolaner (53 reports), Nitenpyram (42 reports).
What is the average age of Russian in adverse event reports? ▼
The average age of Russian at the time of adverse event reports is 7.7 years, with an average weight of 5.1 kg (11.2 lbs).
Does a high number of adverse event reports mean Russian is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Russian safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Guides & Resources
Understanding Adverse Events
What FDA reports are and how they are collected
Breed-Specific Risks
Why some breeds appear in more adverse event reports
Pet Medication Safety
Evaluating medication risks using FDA data
Most Reported Medications
Drugs that appear most in adverse event reports
How FDA CVM Tracks Events
The reporting process and database limitations
Related Data Sources
Data Sources & Methodology
Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.
Russian ranks #129 by total report volume. Death rate (720.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.
Read our methodology — how this data is sourced, computed, and verified.
Related
Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial