Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
548
Total Reports
35
Deaths Reported
640.0%
Death Rate
6.7 yr
Avg Age at Report
Average weight at time of report: 5.0 kg (11.0 lbs)
Top Reported Reactions
Lack of efficacy (ectoparasite) - flea 89
Lethargy (see also Central nervous system depression in 'Neurological') 59
Application site hair loss 55
Vomiting 53
Diarrhoea 32
Not eating 31
Behavioural disorder NOS 27
Emesis (multiple) 27
Anorexia 26
Panting 24
Hyperactivity 22
Ataxia 21
Fever 21
Decreased appetite 21
Lethargy (see also Central nervous system depression in Neurological) 20
Most Referenced Drugs
Fluralaner Spot-On Solution 185
Nitenpyram 64
Fluralaner/Moxidectin Spot-On 48
Spinosad 43
Selamectin;Sarolaner 35
Selamectin 21
Eprinomectin + Esafoxolaner + Praziquantel 20
Imidacloprid + Moxidectin 15
Cefovecin 11
Robenacoxib 9
Emodepside + Praziquantel 8
Buprenorphine 8
Frunevetmab 8
Velagliflozin Proline Monohydrate 8
Mirtazapine 7
Outcome Breakdown
Ongoing
226 (41.2%)
Recovered/Normal
141 (25.7%)
Outcome Unknown
139 (25.3%)
Euthanized
19 (3.5%)
Died
16 (2.9%)
Recovered with Sequela
8 (1.5%)
Gender Distribution
Female 255 (46.5%)
Male 255 (46.5%)
Unknown 24 (4.4%)
Mixed 14 (2.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 1 | |
| 2011 | 3 | |
| 2012 | 13 | |
| 2013 | 10 | |
| 2014 | 25 | |
| 2015 | 30 | |
| 2016 | 13 | |
| 2017 | 53 | |
| 2018 | 65 | |
| 2019 | 39 | |
| 2020 | 47 | |
| 2021 | 50 | |
| 2022 | 39 | |
| 2023 | 58 | |
| 2024 | 46 | |
| 2025 | 56 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #134 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.