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2026 FDA CVM data 479 reports on file official source

Chinese Crested Dog (unspecified) — FDA Adverse Event Profile

Adverse-event records and label data for Chinese Crested Dog (unspecified) (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 37 27.75 18.5 9.25 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Chinese Crested Dog (unspecified) drawn from FDA CVM filings.

Chinese Crested Dog (unspecified) (Dog) has 479 FDA adverse event reports on record, with 18 deaths reported (380.0% death rate) — ranking #141 by report volume. The most frequently reported reaction is Vomiting (129 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 6.7 years.

Total Reports

479

FDA CVM filings

Deaths Reported

18

of 479 reports

Death Rate

380.0%

death-coded share

Avg Age at Report

6.7 yr

6.1 kg avg weight

Death-Coded Outcome Share

Chinese Crested Dog (unspecified) death-coded reports 100.0%
Database median

380.0% of 479 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 6.1 kg (13.5 lbs)

Top Reported Reactions

Vomiting 129
Diarrhoea 46
Lethargy (see also Central nervous system depression in 'Neurological') 46
Emesis 33
Lack of efficacy (ectoparasite) - flea 29
Seizure NOS 24
Lack of efficacy - NOS 19
Ataxia 18
Lack of efficacy (endoparasite) - hookworm 17
Anorexia 17
Pruritus 15
Other abnormal test result NOS 14
Anaphylaxis 13
Elevated alanine aminotransferase (ALT) 13
Behavioural disorder NOS 12

Most Referenced Drugs

Milbemycin Oxime + Spinosad 66
Moxidectin 39
Spinosad 34
Ivermectin + Pyrantel As Pamoate Salt 34
Afoxolaner 31
Pimobendan 29
Milbemycin Oxime + Praziquantel 26
Oclacitinib Maleate 25
Pyrantel Pamoate;Sarolaner 18
Fluralaner Chew Tablets 15
Sarolaner 11
Fluralaner 13.64% 12-Week Chew 11
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 9
Anti-Il31 Mab Mcs Lot #1283563 9
Cyclosporine 8

Outcome Breakdown

Recovered/Normal
162 (37.7%)
Outcome Unknown
133 (30.9%)
Ongoing
107 (24.9%)
Died
11 (2.6%)
Recovered with Sequela
10 (2.3%)
Euthanized
7 (1.6%)

Gender Distribution

Male 240 (50.1%)
Female 223 (46.6%)
Unknown 13 (2.7%)
Mixed 3 (0.6%)

Reports by Year

Year Reports Trend
2010 20
2011 35
2012 29
2013 34
2014 29
2015 27
2016 44
2017 35
2018 34
2019 35
2020 37
2021 26
2022 23
2023 34
2024 19
2025 18
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Chinese Crested Dog (unspecified) sits in the registered size-class taxonomy. Average reported weight: 6.1 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Chinese Crested Dog (unspecified) Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Chinese Crested Dog (unspecified) accounts for 479 submitted reports and currently ranks #141 by report volume within the dog population. Of those reports, 18 involved a death outcome — a 380.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 6.7 years, with an average recorded body weight of 6.1 kg (13.5 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Chinese Crested Dog (unspecified) are Vomiting (129 reports), Diarrhoea (46 reports), Lethargy (see also Central nervous system depression in 'Neurological') (46 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 66 reports and is the single most-referenced drug, followed by Moxidectin (39) and Spinosad (34). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 430 reports with a recorded status is dominated by Recovered/Normal (37.7% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Chinese Crested Dog (unspecified) Adverse Event Data

Chinese Crested Dog (unspecified) has 479 adverse event reports on file. Lower report volumes may reflect a less common breed, lower reporting rates, or genuinely fewer adverse events.

The 380.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 66 reports. This may indicate widespread use of the medication rather than a specific safety concern for Chinese Crested Dog (unspecified).

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Chinese Crested Dog (unspecified)?
There are 479 adverse event reports involving Chinese Crested Dog (unspecified) in the FDA database, with 18 reports involving death (380.0% death rate). Chinese Crested Dog (unspecified) ranks #141 by report volume.
What are the most common adverse reactions reported for Chinese Crested Dog (unspecified)?
The most commonly reported adverse reactions for Chinese Crested Dog (unspecified) are Vomiting (129 reports), Diarrhoea (46 reports), Lethargy (see also Central nervous system depression in 'Neurological') (46 reports), Emesis (33 reports), Lack of efficacy (ectoparasite) - flea (29 reports).
What drugs are most frequently associated with Chinese Crested Dog (unspecified) adverse events?
The drugs most frequently referenced in Chinese Crested Dog (unspecified) adverse event reports are Milbemycin Oxime + Spinosad (66 reports), Moxidectin (39 reports), Spinosad (34 reports), Ivermectin + Pyrantel As Pamoate Salt (34 reports), Afoxolaner (31 reports).
What is the average age of Chinese Crested Dog (unspecified) in adverse event reports?
The average age of Chinese Crested Dog (unspecified) at the time of adverse event reports is 6.7 years, with an average weight of 6.1 kg (13.5 lbs).
Does a high number of adverse event reports mean Chinese Crested Dog (unspecified) is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Chinese Crested Dog (unspecified) safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Chinese Crested Dog (unspecified) ranks #141 by total report volume. Death rate (380.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial