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Breed profile · FDA CVM July 2026 extract

Friesian adverse-event record

Adverse-event filings for Friesian (Horse) in the FDA Center for Veterinary Medicine openFDA extract. Browse horse breeds, reactions, and outcomes below.

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#272 of 510
by report volume (all breeds)
52
FDA CVM reports on file
7.7%
death-coded share of reports
#75 of 275
by death-coded share (≥50 reports)

How the 52 reports break down

By recorded gender -- every report on file for Friesian, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 7 5.25 3.5 1.75 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Friesian drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Friesian ranks #272 of 510 by total reports (52) and #75 of 275 by death-coded share (7.7%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#272
This breed, reports of 510
#75
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Friesian has 52 reports now versus 52 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Friesian changes

Total Reports

52

Below-median volume

Deaths Reported

4

of 52 reports

Death-coded share of reports

7.7%

Above-median death-coded share

Avg Age at Report

11.9 yr

303.8 kg avg weight

Death-Coded Outcome Share

Friesian death-coded reports 7.7%
Cross-breed median

7.7% of 52 friesian reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Friesian's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

8% 72nd percentile Higher share than 72% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Friesian 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 303.8 kg (669.9 lbs)

Top Reported Reactions

Lack of efficacy - NOS 9
Diarrhoea 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Injection site swelling 4
INEFFECTIVE, GASTRIC ULCER(S) 4

Most Referenced Drugs

Omeprazole 10
Pergolide Mesylate 9
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 4
Praziquantel;Moxidectin 4
Polysulfated Glycosaminoglycan 4

Outcome Breakdown

Outcome Unknown
20 (38.5%)
Recovered/Normal
14 (26.9%)
Ongoing
14 (26.9%)
Euthanized
2 (3.8%)
Died
2 (3.8%)

Gender Distribution

Male 34 (65.4%)
Female 16 (30.8%)
Mixed 1 (1.9%)
Unknown 1 (1.9%)

Reports by Year

Year Reports Trend
2011 2
2012 3
2013 3
2014 2
2015 3
2016 3
2018 2
2019 3
2020 4
2021 7
2022 4
2023 5
2024 5
2025 6

Friesian: high death-coded share in the FDA CVM extract

Signature read: Friesian's 7.7% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Friesian sits at #272 of 510 by report volume among all breeds and #21 of 55 among horse breeds, with 52 reports and 4 (7.7%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #75 of 275. Mean age at report: 11.9 years, average weight 303.8 kg (669.9 lbs).

Top reported signs: Lack of efficacy - NOS (9), Diarrhoea (4), Lethargy (see also Central nervous system depression in 'Neurological') (4). Most-referenced drug: Omeprazole (10 reports), followed by Pergolide Mesylate (9) and Ivermectin(1.55%)/Praziquantel(7.75%) Paste (4).

Outcome coding on 52 status-recorded reports is dominated by Outcome Unknown (38.5%). Annual submissions ranged 2-2,025 across 14 years on file.

Horse Breeds With a Similar Report Volume

Showing 6 of 54 horse breeds in our dataset, ranked by closest report volume.

Percheron
52 reports · 11.5% death-coded
Holsteiner
48 reports · 4.2% death-coded
Paso Fino
43 reports · 2.3% death-coded
Trakehner
43 reports · 7.0% death-coded
Belgian Draft, also called Brabant or Brabants trekpaard
41 reports · 12.2% death-coded
Mustang
67 reports · 10.4% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Friesian, both outside the Horse family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (7.7% death-coded here).

Terrier - Bedlington 7.7% · Dog Saint Bernard Dog 7.7% · Dog Domestic Mediumhair 7.7% · Cat Bombay 7.8% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (303.8 kg here).

Highland 289.2 kg · Cattle Brahman 287.8 kg · Cattle Shorthorn - Milking 287.3 kg · Cattle Maine-Anjou 285.4 kg · Cattle

What to do with this horse

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Friesian? ▼
There are 52 adverse event reports involving Friesian in the FDA database, of which 4 were death-coded (7.7% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Friesian ranks #272 of 510 by report volume among all breeds PlainBreed indexes (#21 of 55 among horse breeds).
Where does Friesian sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Friesian is #272 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Horse, it is #21 of 55. Among breeds with at least 50 reports, its death-coded share ranks #75 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Friesian? ▼
The most commonly reported adverse reactions for Friesian are Lack of efficacy - NOS (9 reports), Diarrhoea (4 reports), Lethargy (see also Central nervous system depression in 'Neurological') (4 reports), Injection site swelling (4 reports), INEFFECTIVE, GASTRIC ULCER(S) (4 reports).
What drugs are most frequently associated with Friesian adverse events? ▼
The drugs most frequently referenced in Friesian adverse event reports are Omeprazole (10 reports), Pergolide Mesylate (9 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (4 reports), Praziquantel;Moxidectin (4 reports), Polysulfated Glycosaminoglycan (4 reports).
What is the average age of Friesian in adverse event reports? ▼
The average age of Friesian at the time of adverse event reports is 11.9 years, with an average weight of 303.8 kg (669.9 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Friesian (Horse), extract as of July 2026 extract. 52 reports · 4 death-coded (7.7% of reports, not a mortality rate) · #272 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →