Total Reports
757
FDA CVM filings
Dog /
FDA CVM · 2025 release 757 reports on file
Coton de Tuléar - FDA Adverse Event Profile
Adverse-event records for Coton de Tuléar (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Coton de Tuléar's FDA record: #118 most-reported dog breed, 757 total reports, 2.6% death-coded (20 reports).
- #118
- most-reported dog breed
- 2.6%
- death-coded report share
- 239
- Vomiting - top reaction
- 5.5 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
20
of 757 reports
Death Rate
2.6%
death-coded share
Avg Age at Report
5.5 yr
6.3 kg avg weight
Death-Coded Outcome Share
Coton de Tuléar death-coded reports 2.6%
Cross-breed median
2.6% of 757 coton de tuléar reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 6.3 kg (13.9 lbs)
Top Reported Reactions
Vomiting 239
Lethargy (see also Central nervous system depression in 'Neurological') 90
Diarrhoea 87
Emesis 65
Lack of efficacy (ectoparasite) - flea 43
Emesis (multiple) 31
Anorexia 29
Behavioural disorder NOS 26
Most Referenced Drugs
Milbemycin Oxime + Spinosad 157
Fluralaner Chew Tablets 60
Pyrantel Pamoate;Sarolaner 57
Spinosad 50
Ivermectin + Pyrantel As Pamoate Salt 48
Moxidectin 42
Fluralaner 13.64% 12-Week Chew 35
Afoxolaner 32
Outcome Breakdown
Recovered/Normal
317 (44.0%)
Ongoing
185 (25.7%)
Outcome Unknown
173 (24.0%)
Recovered with Sequela
26 (3.6%)
Died
11 (1.5%)
Euthanized
9 (1.2%)
Gender Distribution
Male 380 (50.2%)
Female 366 (48.3%)
Unknown 10 (1.3%)
Mixed 1 (0.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 15 | |
| 2011 | 26 | |
| 2012 | 53 | |
| 2013 | 69 | |
| 2014 | 57 | |
| 2015 | 38 | |
| 2016 | 56 | |
| 2017 | 58 | |
| 2018 | 56 | |
| 2019 | 46 | |
| 2020 | 50 | |
| 2021 | 55 | |
| 2022 | 41 | |
| 2023 | 60 | |
| 2024 | 49 | |
| 2025 | 28 | |
Coton de Tuléar Pet Health Insights
Coton de Tuléar accounts for 757 FDA adverse event reports, ranking #118 by volume among dog breeds, with 20 reports (2.6%) coded as a death outcome. Mean age at report: 5.5 years, average weight 6.3 kg (13.9 lbs).
Top reported signs: Vomiting (239), Lethargy (see also Central nervous system depression in 'Neurological') (90), Diarrhoea (87). Most-referenced drug: Milbemycin Oxime + Spinosad (157 reports), followed by Fluralaner Chew Tablets (60) and Pyrantel Pamoate;Sarolaner (57).
Outcome coding on 721 status-recorded reports is dominated by Recovered/Normal (44.0%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Coton de Tuléar? ▼
There are 757 adverse event reports involving Coton de Tuléar in the FDA database, with 20 reports involving death (2.6% death rate). Coton de Tuléar ranks #118 by report volume.
What are the most common adverse reactions reported for Coton de Tuléar? ▼
The most commonly reported adverse reactions for Coton de Tuléar are Vomiting (239 reports), Lethargy (see also Central nervous system depression in 'Neurological') (90 reports), Diarrhoea (87 reports), Emesis (65 reports), Lack of efficacy (ectoparasite) - flea (43 reports).
What drugs are most frequently associated with Coton de Tuléar adverse events? ▼
The drugs most frequently referenced in Coton de Tuléar adverse event reports are Milbemycin Oxime + Spinosad (157 reports), Fluralaner Chew Tablets (60 reports), Pyrantel Pamoate;Sarolaner (57 reports), Spinosad (50 reports), Ivermectin + Pyrantel As Pamoate Salt (48 reports).
What is the average age of Coton de Tuléar in adverse event reports? ▼
The average age of Coton de Tuléar at the time of adverse event reports is 5.5 years, with an average weight of 6.3 kg (13.9 lbs).
Does a high number of adverse event reports mean Coton de Tuléar is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Coton de Tuléar safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.