Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
61
Total Reports
5
Deaths Reported
820.0%
Death Rate
4.6 yr
Avg Age at Report
Average weight at time of report: 36.5 kg (80.5 lbs)
Top Reported Reactions
Vomiting 6
Diarrhoea 6
Lack of efficacy (bacteria) - NOS 6
Lack of efficacy (bacteria) - Borrelia 6
Seizure NOS 5
Lack of efficacy (ectoparasite) - tick NOS 4
Lack of efficacy - NOS 3
Emesis 3
Lack of efficacy (endoparasite) - hookworm 3
Death by euthanasia 3
Monocytosis 3
Neoplasia NOS 3
Lethargy (see also Central nervous system depression in Neurological) 3
Lack of efficacy (endoparasite) - roundworm NOS 3
Digestive tract disorder NOS 2
Most Referenced Drugs
Afoxolaner 10
Pyrantel Pamoate;Sarolaner 7
Ivermectin + Pyrantel As Pamoate Salt 5
Oclacitinib Maleate 5
Fluralaner 13.64% 12-Week Chew 5
Milbemycin Oxime + Spinosad 4
Carprofen 4
Recombitek Lyme - 2126.R0 4
Moxidectin 3
Milbemycin/Lufenuron Tablets 3
Bedinvetmab 3
Afoxolaner 150Mg / Moxidectin 720Mcg / Pyrantel 300Mg Chewable Tablet 3
Lufenuron + Milbemycin Oxime 2
Spinosad 2
Metronidazole 2
Outcome Breakdown
Ongoing
25 (41.0%)
Recovered/Normal
18 (29.5%)
Outcome Unknown
13 (21.3%)
Euthanized
3 (4.9%)
Died
2 (3.3%)
Gender Distribution
Male 41 (67.2%)
Female 19 (31.1%)
Unknown 1 (1.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 3 | |
| 2014 | 2 | |
| 2015 | 7 | |
| 2016 | 2 | |
| 2017 | 1 | |
| 2018 | 3 | |
| 2019 | 2 | |
| 2020 | 6 | |
| 2021 | 9 | |
| 2022 | 3 | |
| 2023 | 7 | |
| 2024 | 12 | |
| 2025 | 3 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #262 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.