Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
71
Total Reports
5
Deaths Reported
700.0%
Death Rate
6.1 yr
Avg Age at Report
Average weight at time of report: 16.5 kg (36.4 lbs)
Top Reported Reactions
Vomiting 18
Lack of efficacy (endoparasite) - hookworm 7
Digestive tract disorder NOS 5
Anorexia 4
INEFFECTIVE, ASCARIDS NOS 4
Emesis 4
INEFFECTIVE, HEARTWORM LARVAE 4
Diarrhoea 4
Lack of efficacy - NOS 4
Cough 4
Lethargy (see also Central nervous system depression in 'Neurological') 3
Not eating 3
Disorientation 3
Death 3
Trembling 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 6
Sarolaner 6
Oclacitinib Maleate 5
Milbemycin Oxime + Praziquantel 5
Ivermectin + Pyrantel As Pamoate Salt 4
Pyrantel Pamoate;Sarolaner 4
Milbemycin 3
Lufenuron + Milbemycin Oxime 3
Spinosad 3
Carprofen 3
Milbemycin Oxime 3
Fluralaner Chew Tablets 3
Ivermectin, Pyrantel 2
Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg 2
Meloxicam 2
Outcome Breakdown
Recovered/Normal
27 (42.2%)
Outcome Unknown
18 (28.1%)
Ongoing
13 (20.3%)
Died
3 (4.7%)
Euthanized
2 (3.1%)
Recovered with Sequela
1 (1.6%)
Gender Distribution
Female 38 (53.5%)
Male 32 (45.1%)
Unknown 1 (1.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 4 | |
| 2011 | 5 | |
| 2012 | 5 | |
| 2013 | 6 | |
| 2014 | 1 | |
| 2015 | 9 | |
| 2016 | 6 | |
| 2017 | 7 | |
| 2018 | 7 | |
| 2019 | 5 | |
| 2020 | 6 | |
| 2022 | 6 | |
| 2023 | 2 | |
| 2024 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #245 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.