Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
56
Total Reports
4
Deaths Reported
710.0%
Death Rate
5.7 yr
Avg Age at Report
Average weight at time of report: 17.4 kg (38.4 lbs)
Top Reported Reactions
Vomiting 8
Digestive tract disorder NOS 7
Lack of efficacy (endoparasite) - hookworm 7
Lack of efficacy - NOS 6
Diarrhoea 6
Emesis 6
Lethargy (see also Central nervous system depression in 'Neurological') 6
INEFFECTIVE, ASCARIDS NOS 4
Seizure NOS 4
Anorexia 3
Emesis (multiple) 3
Depression 3
Fever 3
Lack of efficacy (endoparasite) - roundworm NOS 3
Pruritus 2
Most Referenced Drugs
Ivermectin + Pyrantel As Pamoate Salt 10
Milbemycin Oxime + Spinosad 7
Spinosad 5
Afoxolaner 4
Pyrantel Pamoate;Sarolaner 3
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 2
Pimobendan 2
Milbemycin Oxime, Lufenuron 2
Fluralaner Chew Tablets 2
Carprofen 2
Trilostane 2
Moxidectin 2
Milbemycin/Lufenuron Tablets 2
Oclacitinib Maleate 2
Maropitant Citrate 2
Outcome Breakdown
Outcome Unknown
19 (35.8%)
Recovered/Normal
17 (32.1%)
Ongoing
12 (22.6%)
Euthanized
3 (5.7%)
Recovered with Sequela
1 (1.9%)
Died
1 (1.9%)
Gender Distribution
Female 33 (58.9%)
Male 23 (41.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 2 | |
| 2011 | 1 | |
| 2012 | 5 | |
| 2013 | 7 | |
| 2014 | 4 | |
| 2015 | 4 | |
| 2016 | 4 | |
| 2017 | 3 | |
| 2018 | 6 | |
| 2019 | 3 | |
| 2020 | 3 | |
| 2021 | 4 | |
| 2022 | 1 | |
| 2023 | 1 | |
| 2024 | 6 | |
| 2025 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #264 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.