Total Reports
108
FDA CVM filings
Cat /
FDA CVM · 2025 release 108 reports on file
Siberian - FDA Adverse Event Profile
Adverse-event records for Siberian (Cat) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Siberian's FDA record: #225 most-reported cat breed, 108 total reports, 4.6% death-coded (5 reports).
- #225
- most-reported cat breed
- 4.6%
- death-coded report share
- 15
- Lack of efficacy (ectoparasite) - flea - top reaction
- 5.6 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
5
of 108 reports
Death Rate
4.6%
death-coded share
Avg Age at Report
5.6 yr
5.1 kg avg weight
Death-Coded Outcome Share
Siberian death-coded reports 4.6%
Cross-breed median
4.6% of 108 siberian reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 5.1 kg (11.2 lbs)
Top Reported Reactions
Lack of efficacy (ectoparasite) - flea 15
Vomiting 15
Behavioural disorder NOS 13
Lethargy (see also Central nervous system depression in 'Neurological') 13
Not eating 11
Hyperactivity 10
Panting 8
Emesis (multiple) 8
Most Referenced Drugs
Fluralaner Spot-On Solution 23
Spinosad 15
Nitenpyram 12
Buprenorphine 9
Fluralaner/Moxidectin Spot-On 7
Lotilaner 6
Robenacoxib 5
Bexagliflozin 5
Outcome Breakdown
Ongoing
41 (36.9%)
Recovered/Normal
31 (27.9%)
Outcome Unknown
31 (27.9%)
Recovered with Sequela
3 (2.7%)
Died
3 (2.7%)
Euthanized
2 (1.8%)
Gender Distribution
Male 62 (57.4%)
Female 41 (38.0%)
Unknown 5 (4.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 2 | |
| 2013 | 4 | |
| 2014 | 2 | |
| 2015 | 6 | |
| 2016 | 3 | |
| 2017 | 4 | |
| 2018 | 7 | |
| 2019 | 8 | |
| 2020 | 7 | |
| 2021 | 10 | |
| 2022 | 11 | |
| 2023 | 13 | |
| 2024 | 21 | |
| 2025 | 10 | |
Siberian Pet Health Insights
Siberian accounts for 108 FDA adverse event reports, ranking #225 by volume among cat breeds, with 5 reports (4.6%) coded as a death outcome. Mean age at report: 5.6 years, average weight 5.1 kg (11.2 lbs).
Top reported signs: Lack of efficacy (ectoparasite) - flea (15), Vomiting (15), Behavioural disorder NOS (13). Most-referenced drug: Fluralaner Spot-On Solution (23 reports), followed by Spinosad (15) and Nitenpyram (12).
Outcome coding on 111 status-recorded reports is dominated by Ongoing (36.9%). Annual submissions ranged 2,012-2,025 across 14 years on file.
Cat Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Siberian? ▼
There are 108 adverse event reports involving Siberian in the FDA database, with 5 reports involving death (4.6% death rate). Siberian ranks #225 by report volume.
What are the most common adverse reactions reported for Siberian? ▼
The most commonly reported adverse reactions for Siberian are Lack of efficacy (ectoparasite) - flea (15 reports), Vomiting (15 reports), Behavioural disorder NOS (13 reports), Lethargy (see also Central nervous system depression in 'Neurological') (13 reports), Not eating (11 reports).
What drugs are most frequently associated with Siberian adverse events? ▼
The drugs most frequently referenced in Siberian adverse event reports are Fluralaner Spot-On Solution (23 reports), Spinosad (15 reports), Nitenpyram (12 reports), Buprenorphine (9 reports), Fluralaner/Moxidectin Spot-On (7 reports).
What is the average age of Siberian in adverse event reports? ▼
The average age of Siberian at the time of adverse event reports is 5.6 years, with an average weight of 5.1 kg (11.2 lbs).
Does a high number of adverse event reports mean Siberian is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Siberian safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.