Cat /

Siberian

108 adverse event reports submitted to the FDA

Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your cat.
108
Total Reports
5
Deaths Reported
460.0%
Death Rate
5.6 yr
Avg Age at Report
Average weight at time of report: 5.1 kg (11.2 lbs)

Top Reported Reactions

Lack of efficacy (ectoparasite) - flea 15
Vomiting 15
Behavioural disorder NOS 13
Lethargy (see also Central nervous system depression in 'Neurological') 13
Not eating 11
Hyperactivity 10
Panting 8
Emesis (multiple) 8
Lack of efficacy - NOS 7
Anorexia 6
Weight loss 6
Not sleeping 6
Lethargy (see also Central nervous system depression in Neurological) 6
Agitation 5
Application site hair loss 5

Most Referenced Drugs

Fluralaner Spot-On Solution 23
Spinosad 15
Nitenpyram 12
Buprenorphine 9
Fluralaner/Moxidectin Spot-On 7
Lotilaner 6
Robenacoxib 5
Bexagliflozin 5
Gabapentin 4
Itraconazole 4
Fenbendazol Granules 4
Maropitant Citrate 4
Velagliflozin Proline Monohydrate 4
Ketamine 3
Feline Rcp Lv 3

Outcome Breakdown

Ongoing
41 (36.9%)
Recovered/Normal
31 (27.9%)
Outcome Unknown
31 (27.9%)
Recovered with Sequela
3 (2.7%)
Died
3 (2.7%)
Euthanized
2 (1.8%)

Gender Distribution

Male 62 (57.4%)
Female 41 (38.0%)
Unknown 5 (4.6%)

Reports by Year

Year Reports Trend
2012 2
2013 4
2014 2
2015 6
2016 3
2017 4
2018 7
2019 8
2020 7
2021 10
2022 11
2023 13
2024 21
2025 10

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #225 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.