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2026 FDA CVM data 913 reports on file official source

Bulldog - English — FDA Adverse Event Profile

Adverse-event records and label data for Bulldog - English (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 529 396.75 264.5 132.25 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Bulldog - English drawn from FDA CVM filings.

Bulldog - English (Dog) has 913 FDA adverse event reports on record, with 79 deaths reported (870.0% death rate) — ranking #113 by report volume. The most frequently reported reaction is Vomiting (124 cases). The top associated drug is Bedinvetmab. Average age at report: 6.0 years.

Total Reports

913

FDA CVM filings

Deaths Reported

79

of 913 reports

Death Rate

870.0%

death-coded share

Avg Age at Report

6.0 yr

26.2 kg avg weight

Death-Coded Outcome Share

Bulldog - English death-coded reports 100.0%
Database median

870.0% of 913 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 26.2 kg (57.8 lbs)

Top Reported Reactions

Vomiting 124
Lack of efficacy (endoparasite) - heartworm 82
Lethargy (see also Central nervous system depression in Neurological) 81
Diarrhoea 69
Lack of efficacy - NOS 63
Seizure NOS 52
Lack of efficacy (ectoparasite) - flea 51
Death 43
Lack of efficacy (endoparasite) - hookworm 35
Hives (see also Skin) 33
Death by euthanasia 33
Panting 31
Medication error NOS 30
Polydipsia 29
Intentional misuse 26

Most Referenced Drugs

Bedinvetmab 203
Oclacitinib Maleate 129
Pyrantel Pamoate;Sarolaner 108
Moxidectin 77
Fluralaner 13.64% 12-Week Chew 64
Ivermectin + Pyrantel As Pamoate Salt 54
Carprofen 50
Afoxolaner 49
Anti-Il31 Mab Mcs Lot #1283563 45
Gabapentin 41
Prednisone 33
Milbemycin Oxime + Praziquantel 32
Cyclosporine 28
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 28
Ilunocitinib 28

Outcome Breakdown

Ongoing
409 (44.8%)
Outcome Unknown
257 (28.1%)
Recovered/Normal
164 (18.0%)
Died
46 (5.0%)
Euthanized
33 (3.6%)
Recovered with Sequela
4 (0.4%)

Gender Distribution

Female 450 (49.3%)
Male 442 (48.4%)
Unknown 19 (2.1%)
Mixed 2 (0.2%)

Reports by Year

Year Reports Trend
2012 3
2013 1
2017 3
2018 1
2019 1
2020 1
2021 6
2022 12
2023 67
2024 529
2025 289
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Bulldog - English sits in the registered size-class taxonomy. Average reported weight: 26.2 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Bulldog - English Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Bulldog - English accounts for 913 submitted reports and currently ranks #113 by report volume within the dog population. Of those reports, 79 involved a death outcome — a 870.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 6.0 years, with an average recorded body weight of 26.2 kg (57.8 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Bulldog - English are Vomiting (124 reports), Lack of efficacy (endoparasite) - heartworm (82 reports), Lethargy (see also Central nervous system depression in Neurological) (81 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Bedinvetmab appears in 203 reports and is the single most-referenced drug, followed by Oclacitinib Maleate (129) and Pyrantel Pamoate;Sarolaner (108). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 913 reports with a recorded status is dominated by Ongoing (44.8% of coded outcomes). Annual submission volume ranges from 2,012 to 2,025 reports across the 11 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Bulldog - English Adverse Event Data

Bulldog - English has a moderate volume of adverse event reports (913). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 870.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Bedinvetmab, appearing in 203 reports. This may indicate widespread use of the medication rather than a specific safety concern for Bulldog - English.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Bulldog - English?
There are 913 adverse event reports involving Bulldog - English in the FDA database, with 79 reports involving death (870.0% death rate). Bulldog - English ranks #113 by report volume.
What are the most common adverse reactions reported for Bulldog - English?
The most commonly reported adverse reactions for Bulldog - English are Vomiting (124 reports), Lack of efficacy (endoparasite) - heartworm (82 reports), Lethargy (see also Central nervous system depression in Neurological) (81 reports), Diarrhoea (69 reports), Lack of efficacy - NOS (63 reports).
What drugs are most frequently associated with Bulldog - English adverse events?
The drugs most frequently referenced in Bulldog - English adverse event reports are Bedinvetmab (203 reports), Oclacitinib Maleate (129 reports), Pyrantel Pamoate;Sarolaner (108 reports), Moxidectin (77 reports), Fluralaner 13.64% 12-Week Chew (64 reports).
What is the average age of Bulldog - English in adverse event reports?
The average age of Bulldog - English at the time of adverse event reports is 6.0 years, with an average weight of 26.2 kg (57.8 lbs).
Does a high number of adverse event reports mean Bulldog - English is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Bulldog - English safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Bulldog - English ranks #113 by total report volume. Death rate (870.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial