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Breed profile · FDA CVM July 2026 extract

Pony of the Americas adverse-event record

Adverse-event filings for Pony of the Americas (Horse) in the FDA Center for Veterinary Medicine openFDA extract. Browse horse breeds, reactions, and outcomes below.

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#314 of 510
by report volume (all breeds)
33
FDA CVM reports on file
21.2%
death-coded share of reports
6
Death - top reaction

How the 33 reports break down

By recorded gender -- every report on file for Pony of the Americas, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 4 3 2 1 0 2017 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Pony of the Americas drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Pony of the Americas ranks #310 of 510 by total reports (33). Death-coded-share rank requires at least 50 reports. National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#310
This breed, reports of 510

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

Pony of the Americas: what moved between FDA snapshots

Rebuilding the prior openFDA partitions through 2025 Q4 and setting them against the 2026-07-27 openFDA export snapshot puts Pony of the Americas at 33 reports, up from 33 before: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

The comparison is limited to reported-event counts across two snapshots: it is not evidence of a real-world risk or safety change.

Subscribe to Pony of the Americas changes

Total Reports

33

Below-median volume

Deaths Reported

7

of 33 reports

Death-coded share of reports

21.2%

21.2% death-coded

Avg Age at Report

18.2 yr

278.3 kg avg weight

Death-Coded Outcome Share

Pony of the Americas death-coded reports 21.2%
Cross-breed median

21.2% of 33 pony of the americas reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 278.3 kg (613.7 lbs)

Top Reported Reactions

Death 6
Lack of efficacy - NOS 5
Fever 3
Anorexia 3
Abdominal pain 2

Most Referenced Drugs

Pergolide Mesylate 8
Ceftiofur Crystalline Free Acid 3
Pyrantel Tartrate 2
Ketamine Hydrochloride 2
Omeprazole 2

Outcome Breakdown

Recovered/Normal
12 (44.4%)
Outcome Unknown
7 (25.9%)
Died
5 (18.5%)
Euthanized
2 (7.4%)
Ongoing
1 (3.7%)

Gender Distribution

Male 15 (45.5%)
Female 15 (45.5%)
Unknown 2 (6.1%)
Mixed 1 (3.0%)

Reports by Year

Year Reports Trend
2010 1
2011 5
2012 4
2013 1
2014 3
2015 1
2017 3
2019 1
2020 2
2021 1
2022 4
2023 1
2024 4
2025 2

Pony of the Americas: high death-coded share in the FDA CVM extract

Signature read: Pony of the Americas's 21.2% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Pony of the Americas sits at #314 of 510 by report volume among all breeds and #29 of 55 among horse breeds, with 33 reports and 7 (21.2%) death-coded. Mean age at report: 18.2 years, average weight 278.3 kg (613.7 lbs).

Top reported signs: Death (6), Lack of efficacy - NOS (5), Fever (3). Most-referenced drug: Pergolide Mesylate (8 reports), followed by Ceftiofur Crystalline Free Acid (3) and Pyrantel Tartrate (2).

Outcome coding on 27 status-recorded reports is dominated by Recovered/Normal (44.4%). Annual submissions ranged 1-2,025 across 14 years on file.

Horse Breeds With a Similar Report Volume

Showing 6 of 54 horse breeds in our dataset, ranked by closest report volume.

Shetland Pony
33 reports · 21.2% death-coded
Pura Raza Española (Andalusian)
32 reports · 9.4% death-coded
Irish Cob (Tinker)
31 reports · 3.2% death-coded
Welsh Mountain Pony
31 reports · 9.7% death-coded
Rocky Mountain Horse
36 reports · 8.3% death-coded
Standardbred - American
29 reports · 41.4% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Pony of the Americas, both outside the Horse family so the neighborhoods are not species containment (the similar-volume list above stays within species).

What to do with this horse

Filing a report never proves the drug caused the reaction -- and a breed as widely owned as Pony of the Americas will always generate more raw reports.

Frequently Asked Questions

How many FDA adverse event reports involve Pony of the Americas? ▼
There are 33 adverse event reports involving Pony of the Americas in the FDA database, of which 7 were death-coded (21.2% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Pony of the Americas ranks #314 of 510 by report volume among all breeds PlainBreed indexes (#29 of 55 among horse breeds).
Where does Pony of the Americas sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Pony of the Americas is #314 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Horse, it is #29 of 55. It has fewer than 50 reports, so it is outside the death-rate ranking cohort (≥50 reports). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Pony of the Americas? ▼
The most commonly reported adverse reactions for Pony of the Americas are Death (6 reports), Lack of efficacy - NOS (5 reports), Fever (3 reports), Anorexia (3 reports), Abdominal pain (2 reports).
What drugs are most frequently associated with Pony of the Americas adverse events? ▼
The drugs most frequently referenced in Pony of the Americas adverse event reports are Pergolide Mesylate (8 reports), Ceftiofur Crystalline Free Acid (3 reports), Pyrantel Tartrate (2 reports), Ketamine Hydrochloride (2 reports), Omeprazole (2 reports).
What is the average age of Pony of the Americas in adverse event reports? ▼
The average age of Pony of the Americas at the time of adverse event reports is 18.2 years, with an average weight of 278.3 kg (613.7 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pony of the Americas (Horse), extract as of July 2026 extract. 33 reports · 7 death-coded (21.2% of reports, not a mortality rate) · #314 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →