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Breed profile · FDA CVM July 2026 extract

Mixed (Horse) adverse-event record

Adverse-event filings for Mixed (Horse) (Horse) in the FDA Center for Veterinary Medicine openFDA extract. Browse horse breeds, reactions, and outcomes below.

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#230 of 510
by report volume (all breeds)
103
FDA CVM reports on file
15.5%
death-coded share of reports
#28 of 275
by death-coded share (≥50 reports)

How the 103 reports break down

By recorded gender -- every report on file for Mixed (Horse), no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 5 3.75 2.5 1.25 0 2016 2017 2018 2019 2020 2021 2022 2023 Reports filed Death-coded reports
Annual report volume for Mixed (Horse) drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Mixed (Horse) ranks #229 of 510 by total reports (103) and #28 of 275 by death-coded share (15.5%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#229
This breed, reports of 510
#28
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Mixed (Horse) has 103 reports now versus 103 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Mixed (Horse) changes

Total Reports

103

Above-median volume

Deaths Reported

16

of 103 reports

Death-coded share of reports

15.5%

High death-coded share

Avg Age at Report

6.3 yr

345.9 kg avg weight

Death-Coded Outcome Share

Mixed (Horse) death-coded reports 15.5%
Cross-breed median

15.5% of 103 mixed (horse) reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Mixed (Horse)'s death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

16% 90th percentile Higher share than 90% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). Below this entry. 20%–25%: 2 indexed breeds (1%). Below this entry. 25%–30%: 3 indexed breeds (1%). Below this entry. 30%–35%: 4 indexed breeds (1%). Below this entry. 35%–40%: 5 indexed breeds (2%). Below this entry. 40%–45%: 6 indexed breeds (2%). Below this entry. 45%–50%: 3 indexed breeds (1%). Below this entry. 50%–55%: 7 indexed breeds (3%). Below this entry. 55%–60%: 7 indexed breeds (3%). Below this entry. 60%–65%: 21 indexed breeds (8%). Below this entry. 65%–70%: 11 indexed breeds (4%). Below this entry. 70%–75%: 15 indexed breeds (5%). Below this entry. 75%–80%: 13 indexed breeds (5%). Below this entry. 80%–85%: 11 indexed breeds (4%). Below this entry. 85%–90%: 12 indexed breeds (4%). Below this entry. 90%–95%: 12 indexed breeds (4%). Below this entry. 95%–100%: 142 indexed breeds (52%). This entry sits in this band. Mixed (Horse) 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 345.9 kg (762.7 lbs)

Top Reported Reactions

Lip oedema (see also 'Skin') 11
INEFFECTIVE, SEDATION 11
Anorexia 9
INEFFECTIVE, ANESTHESIA 8
Convulsion 8
Application site swelling 7
Death 6
Spasm 6

Most Referenced Drugs

Ivermectin, Praziquantel 19
Ketamine Hydrochloride 13
Detomidine Hydrochloride 5
Fenbendazole 4
Ivermectin 4
Detomidine 4
Pyrantel Tartrate 4
Flunixin Meglumine 3

Outcome Breakdown

Recovered/Normal
24 (45.3%)
Died
15 (28.3%)
Outcome Unknown
9 (17.0%)
Ongoing
3 (5.7%)
Euthanized
2 (3.8%)

Gender Distribution

Mixed 42 (40.8%)
Male 27 (26.2%)
Unknown 20 (19.4%)
Female 14 (13.6%)

Reports by Year

Year Reports Trend
2010 32
2011 27
2012 8
2013 5
2014 11
2015 2
2016 5
2017 1
2018 3
2019 1
2020 2
2021 3
2022 2
2023 1

Mixed (Horse): high death-coded share in the FDA CVM extract

Signature read: Mixed (Horse)'s 15.5% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Mixed (Horse) sits at #230 of 510 by report volume among all breeds and #17 of 55 among horse breeds, with 103 reports and 16 (15.5%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #28 of 275. Mean age at report: 6.3 years, average weight 345.9 kg (762.7 lbs).

Top reported signs: Lip oedema (see also 'Skin') (11), INEFFECTIVE, SEDATION (11), Anorexia (9). Most-referenced drug: Ivermectin, Praziquantel (19 reports), followed by Ketamine Hydrochloride (13) and Detomidine Hydrochloride (5).

Outcome coding on 53 status-recorded reports is dominated by Recovered/Normal (45.3%). Annual submissions ranged 1-2,023 across 14 years on file.

Horse Breeds With a Similar Report Volume

Showing 6 of 54 horse breeds in our dataset, ranked by closest report volume.

Saddlebred - American
94 reports · 16.0% death-coded
Oldenburg
71 reports · 2.8% death-coded
Hanovarian
137 reports · 2.2% death-coded
Mustang
67 reports · 10.4% death-coded
Standardbred (unspecified)
141 reports · 14.9% death-coded
Morgan
145 reports · 10.3% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Mixed (Horse), both outside the Horse family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (15.5% death-coded here).

Rex - Devon 13.6% · Cat Sphynx 13.6% · Cat Domestic (unspecified) 13.4% · Cat European 13.0% · Cat

Similar average weight

Nearest other-species breeds by reported average weight (345.9 kg here).

Longhorn 362.9 kg · Cattle Other Equids (other) 366.8 kg · Other Equids Ayrshire 400.0 kg · Cattle Highland 289.2 kg · Cattle

What to do with this horse

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Mixed (Horse)? ▼
There are 103 adverse event reports involving Mixed (Horse) in the FDA database, of which 16 were death-coded (15.5% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Mixed (Horse) ranks #230 of 510 by report volume among all breeds PlainBreed indexes (#17 of 55 among horse breeds).
Where does Mixed (Horse) sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Mixed (Horse) is #230 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Horse, it is #17 of 55. Among breeds with at least 50 reports, its death-coded share ranks #28 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Mixed (Horse)? ▼
The most commonly reported adverse reactions for Mixed (Horse) are Lip oedema (see also 'Skin') (11 reports), INEFFECTIVE, SEDATION (11 reports), Anorexia (9 reports), INEFFECTIVE, ANESTHESIA (8 reports), Convulsion (8 reports).
What drugs are most frequently associated with Mixed (Horse) adverse events? ▼
The drugs most frequently referenced in Mixed (Horse) adverse event reports are Ivermectin, Praziquantel (19 reports), Ketamine Hydrochloride (13 reports), Detomidine Hydrochloride (5 reports), Fenbendazole (4 reports), Ivermectin (4 reports).
What is the average age of Mixed (Horse) in adverse event reports? ▼
The average age of Mixed (Horse) at the time of adverse event reports is 6.3 years, with an average weight of 345.9 kg (762.7 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Mixed (Horse) (Horse), extract as of July 2026 extract. 103 reports · 16 death-coded (15.5% of reports, not a mortality rate) · #230 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →