Total Reports
103
FDA CVM filings
Horse /
2026 FDA CVM data 103 reports on file official source
Mixed (Horse) — FDA Adverse Event Profile
Adverse-event records and label data for Mixed (Horse) (Horse), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.
Mixed (Horse) (Horse) has 103 FDA adverse event reports on record, with 16 deaths reported (1550.0% death rate) — ranking #228 by report volume. The most frequently reported reaction is Lip oedema (see also 'Skin') (11 cases). The top associated drug is Ivermectin, Praziquantel. Average age at report: 6.3 years.
Deaths Reported
16
of 103 reports
Death Rate
1550.0%
death-coded share
Avg Age at Report
6.3 yr
345.9 kg avg weight
Death-Coded Outcome Share
Mixed (Horse) death-coded reports 100.0%
Database median
1550.0% of 103 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 345.9 kg (762.7 lbs)
Top Reported Reactions
Lip oedema (see also 'Skin') 11
INEFFECTIVE, SEDATION 11
Anorexia 9
INEFFECTIVE, ANESTHESIA 8
Convulsion 8
Application site swelling 7
Death 6
Spasm 6
Hyperactivity 6
Stiff gait 6
Lack of efficacy - NOS 6
Hypersalivation 5
Depression 5
Recumbency 5
Diarrhoea 5
Most Referenced Drugs
Ivermectin, Praziquantel 19
Ketamine Hydrochloride 13
Detomidine Hydrochloride 5
Ivermectin 4
Detomidine 4
Fenbendazole 4
Pyrantel Tartrate 4
Pentobarbital, Phenytoin 3
Flunixin Meglumine 3
Moxidectin 3
Fenbendazol Oral Paste 3
Flunixin Meglumine Injectable 3
Ivermectin + Praziquantel 3
Xylazine 2
Oxibendazole 2
Outcome Breakdown
Recovered/Normal
24 (45.3%)
Died
15 (28.3%)
Outcome Unknown
9 (17.0%)
Ongoing
3 (5.7%)
Euthanized
2 (3.8%)
Gender Distribution
Mixed 42 (40.8%)
Male 27 (26.2%)
Unknown 20 (19.4%)
Female 14 (13.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 32 | |
| 2011 | 27 | |
| 2012 | 8 | |
| 2013 | 5 | |
| 2014 | 11 | |
| 2015 | 2 | |
| 2016 | 5 | |
| 2017 | 1 | |
| 2018 | 3 | |
| 2019 | 1 | |
| 2020 | 2 | |
| 2021 | 3 | |
| 2022 | 2 | |
| 2023 | 1 | |
Mixed (Horse) Pet Health Insights
Across the FDA Center for Veterinary Medicine adverse event database, Mixed (Horse) accounts for 103 submitted reports and currently ranks #228 by report volume within the horse population. Of those reports, 16 involved a death outcome — a 1550.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 6.3 years, with an average recorded body weight of 345.9 kg (762.7 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.
The most frequently reported clinical signs for Mixed (Horse) are Lip oedema (see also 'Skin') (11 reports), INEFFECTIVE, SEDATION (11 reports), Anorexia (9 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Ivermectin, Praziquantel appears in 19 reports and is the single most-referenced drug, followed by Ketamine Hydrochloride (13) and Detomidine Hydrochloride (5). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same horse species.
Outcome coding on the 53 reports with a recorded status is dominated by Recovered/Normal (45.3% of coded outcomes). Annual submission volume ranges from 2,010 to 2,023 reports across the 14 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual horse.
Understanding Mixed (Horse) Adverse Event Data
Mixed (Horse) has 103 adverse event reports on file. Lower report volumes may reflect a less common breed, lower reporting rates, or genuinely fewer adverse events.
The 1550.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.
The most frequently referenced drug in adverse reports is Ivermectin, Praziquantel, appearing in 19 reports. This may indicate widespread use of the medication rather than a specific safety concern for Mixed (Horse).
Other Horse Breeds
Frequently Asked Questions
How many FDA adverse event reports involve Mixed (Horse)? ▼
There are 103 adverse event reports involving Mixed (Horse) in the FDA database, with 16 reports involving death (1550.0% death rate). Mixed (Horse) ranks #228 by report volume.
What are the most common adverse reactions reported for Mixed (Horse)? ▼
The most commonly reported adverse reactions for Mixed (Horse) are Lip oedema (see also 'Skin') (11 reports), INEFFECTIVE, SEDATION (11 reports), Anorexia (9 reports), INEFFECTIVE, ANESTHESIA (8 reports), Convulsion (8 reports).
What drugs are most frequently associated with Mixed (Horse) adverse events? ▼
The drugs most frequently referenced in Mixed (Horse) adverse event reports are Ivermectin, Praziquantel (19 reports), Ketamine Hydrochloride (13 reports), Detomidine Hydrochloride (5 reports), Ivermectin (4 reports), Detomidine (4 reports).
What is the average age of Mixed (Horse) in adverse event reports? ▼
The average age of Mixed (Horse) at the time of adverse event reports is 6.3 years, with an average weight of 345.9 kg (762.7 lbs).
Does a high number of adverse event reports mean Mixed (Horse) is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Mixed (Horse) safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Guides & Resources
Understanding Adverse Events
What FDA reports are and how they are collected
Breed-Specific Risks
Why some breeds appear in more adverse event reports
Pet Medication Safety
Evaluating medication risks using FDA data
Most Reported Medications
Drugs that appear most in adverse event reports
How FDA CVM Tracks Events
The reporting process and database limitations
Related Data Sources
Data Sources & Methodology
Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.
Mixed (Horse) ranks #228 by total report volume. Death rate (1550.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.
Read our methodology — how this data is sourced, computed, and verified.
Related
Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial