Horse /

Breed profile · FDA CVM July 2026 extract

Saddlebred - American adverse-event record

Adverse-event filings for Saddlebred - American (Horse) in the FDA Center for Veterinary Medicine openFDA extract. Browse horse breeds, reactions, and outcomes below.

Verify with FDA CVM →
#236 of 510
by report volume (all breeds)
94
FDA CVM reports on file
16.0%
death-coded share of reports
#26 of 275
by death-coded share (≥50 reports)

How the 94 reports break down

By recorded gender -- every report on file for Saddlebred - American, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 11 8.25 5.5 2.75 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Saddlebred - American drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Saddlebred - American ranks #236 of 510 by total reports (94) and #26 of 275 by death-coded share (16.0%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#236
This breed, reports of 510
#26
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Saddlebred - American has 94 reports now versus 94 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Saddlebred - American changes

Total Reports

94

Above-median volume

Deaths Reported

15

of 94 reports

Death-coded share of reports

16.0%

Highest death-coded share

Avg Age at Report

14.6 yr

432.3 kg avg weight

Death-Coded Outcome Share

Saddlebred - American death-coded reports 16.0%
Cross-breed median

16.0% of 94 saddlebred - american reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Saddlebred - American's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

16% 91st percentile Higher share than 91% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). Below this entry. 20%–25%: 2 indexed breeds (1%). Below this entry. 25%–30%: 3 indexed breeds (1%). Below this entry. 30%–35%: 4 indexed breeds (1%). Below this entry. 35%–40%: 5 indexed breeds (2%). Below this entry. 40%–45%: 6 indexed breeds (2%). Below this entry. 45%–50%: 3 indexed breeds (1%). Below this entry. 50%–55%: 7 indexed breeds (3%). Below this entry. 55%–60%: 7 indexed breeds (3%). Below this entry. 60%–65%: 21 indexed breeds (8%). Below this entry. 65%–70%: 11 indexed breeds (4%). Below this entry. 70%–75%: 15 indexed breeds (5%). Below this entry. 75%–80%: 13 indexed breeds (5%). Below this entry. 80%–85%: 11 indexed breeds (4%). Below this entry. 85%–90%: 12 indexed breeds (4%). Below this entry. 90%–95%: 12 indexed breeds (4%). Below this entry. 95%–100%: 142 indexed breeds (52%). This entry sits in this band. Saddlebred - American 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 432.3 kg (953.2 lbs)

Top Reported Reactions

Lack of efficacy - NOS 11
Death by euthanasia 10
Colic 10
Other abnormal test result NOS 6
Fever 6

Most Referenced Drugs

Pergolide Mesylate 13
Ceftiofur Crystalline Free Acid 13
Detomidine Hydrochloride 9
Omeprazole 9
Ivermectin + Praziquantel 8

Outcome Breakdown

Recovered/Normal
36 (41.4%)
Outcome Unknown
24 (27.6%)
Ongoing
11 (12.6%)
Euthanized
9 (10.3%)
Died
6 (6.9%)
Recovered with Sequela
1 (1.1%)

Gender Distribution

Male 41 (43.6%)
Female 40 (42.6%)
Unknown 7 (7.4%)
Mixed 6 (6.4%)

Reports by Year

Year Reports Trend
2010 2
2011 7
2012 8
2013 1
2014 2
2015 3
2016 9
2017 7
2018 11
2019 7
2020 10
2021 4
2022 4
2023 7
2024 7
2025 5

Saddlebred - American: high death-coded share in the FDA CVM extract

Signature read: Saddlebred - American's 16.0% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Saddlebred - American sits at #236 of 510 by report volume among all breeds and #18 of 55 among horse breeds, with 94 reports and 15 (16.0%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #26 of 275. Mean age at report: 14.6 years, average weight 432.3 kg (953.2 lbs).

Top reported signs: Lack of efficacy - NOS (11), Death by euthanasia (10), Colic (10). Most-referenced drug: Pergolide Mesylate (13 reports), followed by Ceftiofur Crystalline Free Acid (13) and Detomidine Hydrochloride (9).

Outcome coding on 87 status-recorded reports is dominated by Recovered/Normal (41.4%). Annual submissions ranged 1-2,025 across 16 years on file.

Horse Breeds With a Similar Report Volume

Showing 6 of 54 horse breeds in our dataset, ranked by closest report volume.

Mixed (Horse)
103 reports · 15.5% death-coded
Oldenburg
71 reports · 2.8% death-coded
Mustang
67 reports · 10.4% death-coded
Friesian
52 reports · 7.7% death-coded
Percheron
52 reports · 11.5% death-coded
Hanovarian
137 reports · 2.2% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Saddlebred - American, both outside the Horse family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (16.0% death-coded here).

Rex - Devon 13.6% · Cat Sphynx 13.6% · Cat Domestic (unspecified) 13.4% · Cat European 13.0% · Cat

What to do with this horse

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Saddlebred - American? ▼
There are 94 adverse event reports involving Saddlebred - American in the FDA database, of which 15 were death-coded (16.0% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Saddlebred - American ranks #236 of 510 by report volume among all breeds PlainBreed indexes (#18 of 55 among horse breeds).
Where does Saddlebred - American sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Saddlebred - American is #236 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Horse, it is #18 of 55. Among breeds with at least 50 reports, its death-coded share ranks #26 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Saddlebred - American? ▼
The most commonly reported adverse reactions for Saddlebred - American are Lack of efficacy - NOS (11 reports), Death by euthanasia (10 reports), Colic (10 reports), Other abnormal test result NOS (6 reports), Fever (6 reports).
What drugs are most frequently associated with Saddlebred - American adverse events? ▼
The drugs most frequently referenced in Saddlebred - American adverse event reports are Pergolide Mesylate (13 reports), Ceftiofur Crystalline Free Acid (13 reports), Detomidine Hydrochloride (9 reports), Omeprazole (9 reports), Ivermectin + Praziquantel (8 reports).
What is the average age of Saddlebred - American in adverse event reports? ▼
The average age of Saddlebred - American at the time of adverse event reports is 14.6 years, with an average weight of 432.3 kg (953.2 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Saddlebred - American (Horse), extract as of July 2026 extract. 94 reports · 15 death-coded (16.0% of reports, not a mortality rate) · #236 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →