Total Reports
159
FDA CVM filings
Horse /
2026 FDA CVM data 159 reports on file official source
Miniature — FDA Adverse Event Profile
Adverse-event records and label data for Miniature (Horse), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.
Miniature (Horse) has 159 FDA adverse event reports on record, with 25 deaths reported (1570.0% death rate) — ranking #199 by report volume. The most frequently reported reaction is Anorexia (22 cases). The top associated drug is Pergolide Mesylate. Average age at report: 11.9 years.
Deaths Reported
25
of 159 reports
Death Rate
1570.0%
death-coded share
Avg Age at Report
11.9 yr
116.5 kg avg weight
Death-Coded Outcome Share
Miniature death-coded reports 100.0%
Database median
1570.0% of 159 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 116.5 kg (256.9 lbs)
Top Reported Reactions
Anorexia 22
Ataxia 16
Fever 14
Depression 12
Lethargy (see also Central nervous system depression in 'Neurological') 12
Colic 12
Tachycardia 11
Recumbency 10
Death 10
Overdose 10
Other abnormal test result NOS 9
Twitching 8
Behavioural disorder NOS 8
Death by euthanasia 8
Lack of efficacy - NOS 8
Most Referenced Drugs
Pergolide Mesylate 36
Detomidine Hydrochloride 15
Moxidectin 10
Ivermectin 8
Ceftiofur Crystalline Free Acid 7
Ketamine Hydrochloride 6
Omeprazole 6
Ivermectin + Praziquantel 6
Praziquantel;Moxidectin 6
Firocoxib 5
Flunixin Meglumine Injectable 5
Detomidine 4
Pyrantel Tartrate 4
Clenbuterol Hydrochloride 4
Butorphanol 4
Outcome Breakdown
Recovered/Normal
64 (47.4%)
Outcome Unknown
34 (25.2%)
Died
14 (10.4%)
Euthanized
11 (8.1%)
Ongoing
10 (7.4%)
Recovered with Sequela
2 (1.5%)
Gender Distribution
Male 74 (46.5%)
Female 54 (34.0%)
Unknown 27 (17.0%)
Mixed 4 (2.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 8 | |
| 2011 | 11 | |
| 2012 | 13 | |
| 2013 | 14 | |
| 2014 | 13 | |
| 2015 | 5 | |
| 2016 | 6 | |
| 2017 | 8 | |
| 2018 | 9 | |
| 2019 | 10 | |
| 2020 | 19 | |
| 2021 | 11 | |
| 2022 | 14 | |
| 2023 | 9 | |
| 2024 | 6 | |
| 2025 | 3 | |
Miniature Pet Health Insights
Across the FDA Center for Veterinary Medicine adverse event database, Miniature accounts for 159 submitted reports and currently ranks #199 by report volume within the horse population. Of those reports, 25 involved a death outcome — a 1570.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 11.9 years, with an average recorded body weight of 116.5 kg (256.9 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.
The most frequently reported clinical signs for Miniature are Anorexia (22 reports), Ataxia (16 reports), Fever (14 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Pergolide Mesylate appears in 36 reports and is the single most-referenced drug, followed by Detomidine Hydrochloride (15) and Moxidectin (10). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same horse species.
Outcome coding on the 135 reports with a recorded status is dominated by Recovered/Normal (47.4% of coded outcomes). Annual submission volume ranges from 2,010 to 2,025 reports across the 16 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual horse.
Understanding Miniature Adverse Event Data
Miniature has 159 adverse event reports on file. Lower report volumes may reflect a less common breed, lower reporting rates, or genuinely fewer adverse events.
The 1570.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.
The most frequently referenced drug in adverse reports is Pergolide Mesylate, appearing in 36 reports. This may indicate widespread use of the medication rather than a specific safety concern for Miniature.
Other Horse Breeds
Frequently Asked Questions
How many FDA adverse event reports involve Miniature? ▼
There are 159 adverse event reports involving Miniature in the FDA database, with 25 reports involving death (1570.0% death rate). Miniature ranks #199 by report volume.
What are the most common adverse reactions reported for Miniature? ▼
The most commonly reported adverse reactions for Miniature are Anorexia (22 reports), Ataxia (16 reports), Fever (14 reports), Depression (12 reports), Lethargy (see also Central nervous system depression in 'Neurological') (12 reports).
What drugs are most frequently associated with Miniature adverse events? ▼
The drugs most frequently referenced in Miniature adverse event reports are Pergolide Mesylate (36 reports), Detomidine Hydrochloride (15 reports), Moxidectin (10 reports), Ivermectin (8 reports), Ceftiofur Crystalline Free Acid (7 reports).
What is the average age of Miniature in adverse event reports? ▼
The average age of Miniature at the time of adverse event reports is 11.9 years, with an average weight of 116.5 kg (256.9 lbs).
Does a high number of adverse event reports mean Miniature is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Miniature safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Guides & Resources
Understanding Adverse Events
What FDA reports are and how they are collected
Breed-Specific Risks
Why some breeds appear in more adverse event reports
Pet Medication Safety
Evaluating medication risks using FDA data
Most Reported Medications
Drugs that appear most in adverse event reports
How FDA CVM Tracks Events
The reporting process and database limitations
Related Data Sources
Data Sources & Methodology
Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.
Miniature ranks #199 by total report volume. Death rate (1570.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.
Read our methodology — how this data is sourced, computed, and verified.
Related
Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial