Total Reports
159
FDA CVM filings
Horse /
FDA CVM · 2025 release 159 reports on file
Appaloosa - FDA Adverse Event Profile
Adverse-event records for Appaloosa (Horse) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 159 reports on file, Appaloosa sits at #198 among horse breeds by volume; death-coded share is 10.1% (16 reports).
- #198
- most-reported horse breed
- 10.1%
- death-coded report share
- 14
- Application site swelling - top reaction
- 16.0 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
16
of 159 reports
Death Rate
10.1%
death-coded share
Avg Age at Report
16.0 yr
433.9 kg avg weight
Death-Coded Outcome Share
Appaloosa death-coded reports 10.1%
Cross-breed median
10.1% of 159 appaloosa reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 433.9 kg (956.7 lbs)
Top Reported Reactions
Application site swelling 14
Injection site swelling 11
Lack of efficacy - NOS 11
INEFFECTIVE, SEDATION 10
Lethargy (see also Central nervous system depression in 'Neurological') 9
Lip oedema (see also 'Skin') 8
Tachypnoea 8
Colic 8
Most Referenced Drugs
Pergolide Mesylate 22
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 13
Detomidine Hydrochloride 12
Omeprazole 12
Ceftiofur Crystalline Free Acid 10
Ivermectin, Praziquantel 8
Ivermectin + Praziquantel 7
Xylazine 6
Outcome Breakdown
Recovered/Normal
52 (38.5%)
Outcome Unknown
51 (37.8%)
Ongoing
16 (11.9%)
Died
10 (7.4%)
Euthanized
6 (4.4%)
Gender Distribution
Male 94 (59.1%)
Female 59 (37.1%)
Mixed 5 (3.1%)
Unknown 1 (0.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 15 | |
| 2011 | 8 | |
| 2012 | 13 | |
| 2013 | 10 | |
| 2014 | 9 | |
| 2015 | 9 | |
| 2016 | 10 | |
| 2017 | 13 | |
| 2018 | 10 | |
| 2019 | 11 | |
| 2020 | 10 | |
| 2021 | 8 | |
| 2022 | 9 | |
| 2023 | 8 | |
| 2024 | 6 | |
| 2025 | 10 | |
Appaloosa Pet Health Insights
Appaloosa accounts for 159 FDA adverse event reports, ranking #198 by volume among horse breeds, with 16 reports (10.1%) coded as a death outcome. Mean age at report: 16.0 years, average weight 433.9 kg (956.7 lbs).
Top reported signs: Application site swelling (14), Injection site swelling (11), Lack of efficacy - NOS (11). Most-referenced drug: Pergolide Mesylate (22 reports), followed by Ivermectin(1.55%)/Praziquantel(7.75%) Paste (13) and Detomidine Hydrochloride (12).
Outcome coding on 135 status-recorded reports is dominated by Recovered/Normal (38.5%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Horse Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Appaloosa? ▼
There are 159 adverse event reports involving Appaloosa in the FDA database, with 16 reports involving death (10.1% death rate). Appaloosa ranks #198 by report volume.
What are the most common adverse reactions reported for Appaloosa? ▼
The most commonly reported adverse reactions for Appaloosa are Application site swelling (14 reports), Injection site swelling (11 reports), Lack of efficacy - NOS (11 reports), INEFFECTIVE, SEDATION (10 reports), Lethargy (see also Central nervous system depression in 'Neurological') (9 reports).
What drugs are most frequently associated with Appaloosa adverse events? ▼
The drugs most frequently referenced in Appaloosa adverse event reports are Pergolide Mesylate (22 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (13 reports), Detomidine Hydrochloride (12 reports), Omeprazole (12 reports), Ceftiofur Crystalline Free Acid (10 reports).
What is the average age of Appaloosa in adverse event reports? ▼
The average age of Appaloosa at the time of adverse event reports is 16.0 years, with an average weight of 433.9 kg (956.7 lbs).
Does a high number of adverse event reports mean Appaloosa is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Appaloosa safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.