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Breed profile · FDA CVM July 2026 extract

Appaloosa adverse-event record

Adverse-event filings for Appaloosa (Horse) in the FDA Center for Veterinary Medicine openFDA extract. Browse horse breeds, reactions, and outcomes below.

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#196 of 510
by report volume (all breeds)
167
FDA CVM reports on file
10.2%
death-coded share of reports
#47 of 275
by death-coded share (≥50 reports)

How the 167 reports break down

By recorded gender -- every report on file for Appaloosa, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 16 12 8 4 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Appaloosa drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Appaloosa ranks #196 of 510 by total reports (167) and #47 of 275 by death-coded share (10.2%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#196
This breed, reports of 510
#47
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Appaloosa has 167 reports now versus 165 in that prior snapshot: 2 more (1.2%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Appaloosa changes

Total Reports

167

Above-median volume

Deaths Reported

17

of 167 reports

Death-coded share of reports

10.2%

High death-coded share

Avg Age at Report

15.9 yr

434.1 kg avg weight

Death-Coded Outcome Share

Appaloosa death-coded reports 10.2%
Cross-breed median

10.2% of 167 appaloosa reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Appaloosa's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

10% 83rd percentile Higher share than 83% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). Below this entry. 20%–25%: 2 indexed breeds (1%). Below this entry. 25%–30%: 3 indexed breeds (1%). Below this entry. 30%–35%: 4 indexed breeds (1%). Below this entry. 35%–40%: 5 indexed breeds (2%). Below this entry. 40%–45%: 6 indexed breeds (2%). Below this entry. 45%–50%: 3 indexed breeds (1%). Below this entry. 50%–55%: 7 indexed breeds (3%). Below this entry. 55%–60%: 7 indexed breeds (3%). Below this entry. 60%–65%: 21 indexed breeds (8%). Below this entry. 65%–70%: 11 indexed breeds (4%). Below this entry. 70%–75%: 15 indexed breeds (5%). Below this entry. 75%–80%: 13 indexed breeds (5%). Below this entry. 80%–85%: 11 indexed breeds (4%). Below this entry. 85%–90%: 12 indexed breeds (4%). Below this entry. 90%–95%: 12 indexed breeds (4%). Below this entry. 95%–100%: 142 indexed breeds (52%). This entry sits in this band. Appaloosa 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 434.1 kg (957.2 lbs)

Top Reported Reactions

Application site swelling 14
Injection site swelling 12
Lack of efficacy - NOS 12
INEFFECTIVE, SEDATION 10
Tachypnoea 9
Lethargy (see also Central nervous system depression in 'Neurological') 9
Lip oedema (see also 'Skin') 8
Death 8

Most Referenced Drugs

Pergolide Mesylate 24
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 13
Detomidine Hydrochloride 13
Omeprazole 13
Ceftiofur Crystalline Free Acid 10
Ivermectin, Praziquantel 8
Ivermectin + Praziquantel 8
Xylazine 6

Outcome Breakdown

Recovered/Normal
56 (39.2%)
Outcome Unknown
52 (36.4%)
Ongoing
18 (12.6%)
Died
11 (7.7%)
Euthanized
6 (4.2%)

Gender Distribution

Male 98 (58.7%)
Female 62 (37.1%)
Mixed 5 (3.0%)
Unknown 2 (1.2%)

Reports by Year

Year Reports Trend
2010 15
2011 8
2012 13
2013 10
2014 9
2015 9
2016 10
2017 13
2018 10
2019 11
2020 10
2021 8
2022 9
2023 8
2024 6
2025 16
2026 2

Appaloosa: high death-coded share in the FDA CVM extract

Signature read: Appaloosa's 10.2% death-coded share is in the upper third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Appaloosa sits at #196 of 510 by report volume among all breeds and #11 of 55 among horse breeds, with 167 reports and 17 (10.2%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #47 of 275. Mean age at report: 15.9 years, average weight 434.1 kg (957.2 lbs).

Top reported signs: Application site swelling (14), Injection site swelling (12), Lack of efficacy - NOS (12). Most-referenced drug: Pergolide Mesylate (24 reports), followed by Ivermectin(1.55%)/Praziquantel(7.75%) Paste (13) and Detomidine Hydrochloride (13).

Outcome coding on 143 status-recorded reports is dominated by Recovered/Normal (39.2%). Annual submissions ranged 2-2,026 across 17 years on file.

Horse Breeds With a Similar Report Volume

Showing 6 of 54 horse breeds in our dataset, ranked by closest report volume.

Miniature
164 reports · 15.9% death-coded
Pony (unspecified)
151 reports · 11.9% death-coded
Warmblood - Dutch
184 reports · 2.7% death-coded
Tennessee Walking Horse
186 reports · 12.9% death-coded
Morgan
145 reports · 10.3% death-coded
Crossbred Equine/horse
190 reports · 7.9% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for Appaloosa, both outside the Horse family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (10.2% death-coded here).

Domestic ferret (Pet ferret) 9.9% · Ferret Mastiff (unspecified) 9.8% · Dog Himalayan 10.6% · Cat Persian 9.7% · Cat

What to do with this horse

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Appaloosa? ▼
There are 167 adverse event reports involving Appaloosa in the FDA database, of which 17 were death-coded (10.2% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Appaloosa ranks #196 of 510 by report volume among all breeds PlainBreed indexes (#11 of 55 among horse breeds).
Where does Appaloosa sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Appaloosa is #196 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Horse, it is #11 of 55. Among breeds with at least 50 reports, its death-coded share ranks #47 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Appaloosa? ▼
The most commonly reported adverse reactions for Appaloosa are Application site swelling (14 reports), Injection site swelling (12 reports), Lack of efficacy - NOS (12 reports), INEFFECTIVE, SEDATION (10 reports), Tachypnoea (9 reports).
What drugs are most frequently associated with Appaloosa adverse events? ▼
The drugs most frequently referenced in Appaloosa adverse event reports are Pergolide Mesylate (24 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (13 reports), Detomidine Hydrochloride (13 reports), Omeprazole (13 reports), Ceftiofur Crystalline Free Acid (10 reports).
What is the average age of Appaloosa in adverse event reports? ▼
The average age of Appaloosa at the time of adverse event reports is 15.9 years, with an average weight of 434.1 kg (957.2 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Appaloosa (Horse), extract as of July 2026 extract. 167 reports · 17 death-coded (10.2% of reports, not a mortality rate) · #196 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →