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Breed profile · FDA CVM July 2026 extract

Clydesdale adverse-event record

Adverse-event filings for Clydesdale (Horse) in the FDA Center for Veterinary Medicine openFDA extract. Browse horse breeds, reactions, and outcomes below.

#367 of 510
by report volume (all breeds)
19
FDA CVM reports on file
26.3%
death-coded share of reports
2
Application site swelling - top reaction

How the 19 reports break down

By recorded gender -- every report on file for Clydesdale, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 2 1.5 1 0.5 0 2016 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Clydesdale drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Clydesdale ranks #364 of 510 by total reports (19). Death-coded-share rank requires at least 50 reports. National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#364
This breed, reports of 510

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Clydesdale has 19 reports now versus 19 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Clydesdale changes

Total Reports

19

Below-median volume

Deaths Reported

5

of 19 reports

Death-coded share of reports

26.3%

26.3% death-coded

Avg Age at Report

8.3 yr

269.0 kg avg weight

Death-Coded Outcome Share

Clydesdale death-coded reports 26.3%
Cross-breed median

26.3% of 19 clydesdale reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 269.0 kg (593.1 lbs)

Top Reported Reactions

Application site swelling 2
Localised oedema (not application site) 2
Death by euthanasia 2
Fever 2
Uncoded sign 2

Most Referenced Drugs

Detomidine Hydrochloride 2
Acepromazine Maleate 2
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 2
Omeprazole 37% Oral Paste 2
Polysulfated Glycosaminoglycan 2

Outcome Breakdown

Recovered/Normal
6 (31.6%)
Outcome Unknown
5 (26.3%)
Euthanized
3 (15.8%)
Ongoing
3 (15.8%)
Died
2 (10.5%)

Gender Distribution

Male 12 (63.2%)
Female 5 (26.3%)
Mixed 1 (5.3%)
Unknown 1 (5.3%)

Reports by Year

Year Reports Trend
2010 1
2012 1
2013 2
2014 2
2015 1
2016 2
2019 1
2020 1
2021 1
2022 2
2023 2
2024 1
2025 2

Clydesdale: high death-coded share in the FDA CVM extract

Signature read: 19 reports place Clydesdale in the lower third of breed filing volume (#367 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Clydesdale sits at #367 of 510 by report volume among all breeds and #39 of 55 among horse breeds, with 19 reports and 5 (26.3%) death-coded. Mean age at report: 8.3 years, average weight 269.0 kg (593.1 lbs).

Top reported signs: Application site swelling (2), Localised oedema (not application site) (2), Death by euthanasia (2). Most-referenced drug: Detomidine Hydrochloride (2 reports), followed by Acepromazine Maleate (2) and Ivermectin(1.55%)/Praziquantel(7.75%) Paste (2).

Outcome coding on 19 status-recorded reports is dominated by Recovered/Normal (31.6%). Annual submissions ranged 1-2,025 across 13 years on file.

Horse Breeds With a Similar Report Volume

Showing 6 of 54 horse breeds in our dataset, ranked by closest report volume.

Nationwide breeds with similar profiles

Sparse-volume peer sets for Clydesdale drawn from openFDA outside the Horse family so the neighborhoods are not species containment (the similar-volume list above stays within species).

What to do with this horse

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Clydesdale?
There are 19 adverse event reports involving Clydesdale in the FDA database, of which 5 were death-coded (26.3% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Clydesdale ranks #367 of 510 by report volume among all breeds PlainBreed indexes (#39 of 55 among horse breeds).
Where does Clydesdale sit among other breeds in PlainBreed's corpus?
According to FDA CVM report volume, Clydesdale is #367 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Horse, it is #39 of 55. It has fewer than 50 reports, so it is outside the death-rate ranking cohort (≥50 reports). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Clydesdale?
The most commonly reported adverse reactions for Clydesdale are Application site swelling (2 reports), Localised oedema (not application site) (2 reports), Death by euthanasia (2 reports), Fever (2 reports), Uncoded sign (2 reports).
What drugs are most frequently associated with Clydesdale adverse events?
The drugs most frequently referenced in Clydesdale adverse event reports are Detomidine Hydrochloride (2 reports), Acepromazine Maleate (2 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (2 reports), Omeprazole 37% Oral Paste (2 reports), Polysulfated Glycosaminoglycan (2 reports).
What is the average age of Clydesdale in adverse event reports?
The average age of Clydesdale at the time of adverse event reports is 8.3 years, with an average weight of 269.0 kg (593.1 lbs).

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Clydesdale (Horse), extract as of July 2026 extract. 19 reports · 5 death-coded (26.3% of reports, not a mortality rate) · #367 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →