Total Reports
18
FDA CVM filings
Sheep /
2026 FDA CVM data 18 reports on file official source
Crossbred Ovine/sheep — FDA Adverse Event Profile
Adverse-event records and label data for Crossbred Ovine/sheep (Sheep), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.
Crossbred Ovine/sheep (Sheep) has 18 FDA adverse event reports on record, with 9 deaths reported (5000.0% death rate) — ranking #369 by report volume. The most frequently reported reaction is Death (6 cases). The top associated drug is Progesterone. Average age at report: 0.9 years.
Deaths Reported
9
of 18 reports
Death Rate
5000.0%
death-coded share
Avg Age at Report
0.9 yr
52.6 kg avg weight
Death-Coded Outcome Share
Crossbred Ovine/sheep death-coded reports 100.0%
Database median
5000.0% of 18 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 52.6 kg (116.0 lbs)
Top Reported Reactions
Death 6
Hyperextension 5
INEFFECTIVE, ESTRUS INDUCTION 5
Lack of efficacy - NOS 3
Behavioural disorder NOS 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Drug administration duration too long 2
Sudden death 2
Blindness 1
Ocular discharge 1
Anorexia 1
Recumbency 1
Dehydration 1
Depression 1
INEFFECTIVE, PARASITE(S) NOS 1
Most Referenced Drugs
Progesterone 6
Moxidectin 2
Oxytetracycline Hydrochloride 1
Ivermectin 1
Zeranol 1
Monensin Sodium 1
Doramectin; Phenol 1
Oxytetracycline Dihydrate (Oxytetracycline Amphoteric) 1
Levamisole 1
Gamithromycin 1
Albendazole 1
Eprinomectin 1
Outcome Breakdown
Outcome Unknown
11 (55.0%)
Died
9 (45.0%)
Gender Distribution
Female 10 (55.6%)
Mixed 5 (27.8%)
Male 2 (11.1%)
Unknown 1 (5.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 2 | |
| 2011 | 1 | |
| 2012 | 1 | |
| 2013 | 4 | |
| 2014 | 2 | |
| 2016 | 3 | |
| 2017 | 1 | |
| 2018 | 1 | |
| 2020 | 1 | |
| 2021 | 1 | |
| 2024 | 1 | |
Crossbred Ovine/sheep Pet Health Insights
Across the FDA Center for Veterinary Medicine adverse event database, Crossbred Ovine/sheep accounts for 18 submitted reports and currently ranks #369 by report volume within the sheep population. Of those reports, 9 involved a death outcome — a 5000.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 0.9 years, with an average recorded body weight of 52.6 kg (116.0 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.
The most frequently reported clinical signs for Crossbred Ovine/sheep are Death (6 reports), Hyperextension (5 reports), INEFFECTIVE, ESTRUS INDUCTION (5 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Progesterone appears in 6 reports and is the single most-referenced drug, followed by Moxidectin (2) and Oxytetracycline Hydrochloride (1). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same sheep species.
Outcome coding on the 20 reports with a recorded status is dominated by Outcome Unknown (55.0% of coded outcomes). Annual submission volume ranges from 2,010 to 2,024 reports across the 11 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual sheep.
Understanding Crossbred Ovine/sheep Adverse Event Data
Crossbred Ovine/sheep has 18 adverse event reports on file. Lower report volumes may reflect a less common breed, lower reporting rates, or genuinely fewer adverse events.
The 5000.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.
The most frequently referenced drug in adverse reports is Progesterone, appearing in 6 reports. This may indicate widespread use of the medication rather than a specific safety concern for Crossbred Ovine/sheep.
Other Sheep Breeds
Frequently Asked Questions
How many FDA adverse event reports involve Crossbred Ovine/sheep? ▼
There are 18 adverse event reports involving Crossbred Ovine/sheep in the FDA database, with 9 reports involving death (5000.0% death rate). Crossbred Ovine/sheep ranks #369 by report volume.
What are the most common adverse reactions reported for Crossbred Ovine/sheep? ▼
The most commonly reported adverse reactions for Crossbred Ovine/sheep are Death (6 reports), Hyperextension (5 reports), INEFFECTIVE, ESTRUS INDUCTION (5 reports), Lack of efficacy - NOS (3 reports), Behavioural disorder NOS (2 reports).
What drugs are most frequently associated with Crossbred Ovine/sheep adverse events? ▼
The drugs most frequently referenced in Crossbred Ovine/sheep adverse event reports are Progesterone (6 reports), Moxidectin (2 reports), Oxytetracycline Hydrochloride (1 reports), Ivermectin (1 reports), Zeranol (1 reports).
What is the average age of Crossbred Ovine/sheep in adverse event reports? ▼
The average age of Crossbred Ovine/sheep at the time of adverse event reports is 0.9 years, with an average weight of 52.6 kg (116.0 lbs).
Does a high number of adverse event reports mean Crossbred Ovine/sheep is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Crossbred Ovine/sheep safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Guides & Resources
Understanding Adverse Events
What FDA reports are and how they are collected
Breed-Specific Risks
Why some breeds appear in more adverse event reports
Pet Medication Safety
Evaluating medication risks using FDA data
Most Reported Medications
Drugs that appear most in adverse event reports
How FDA CVM Tracks Events
The reporting process and database limitations
Related Data Sources
Data Sources & Methodology
Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.
Crossbred Ovine/sheep ranks #369 by total report volume. Death rate (5000.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.
Read our methodology — how this data is sourced, computed, and verified.
Related
Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial