Total Reports
159
FDA CVM filings
Dog /
FDA CVM · 2025 release 159 reports on file
Terrier - Manchester - FDA Adverse Event Profile
Adverse-event records for Terrier - Manchester (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 159 reports on file, Terrier - Manchester sits at #197 among dog breeds by volume; death-coded share is 5.0% (8 reports).
- #197
- most-reported dog breed
- 5.0%
- death-coded report share
- 36
- Vomiting - top reaction
- 6.8 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
8
of 159 reports
Death Rate
5.0%
death-coded share
Avg Age at Report
6.8 yr
8.7 kg avg weight
Death-Coded Outcome Share
Terrier - Manchester death-coded reports 5.0%
Cross-breed median
5.0% of 159 terrier - manchester reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 8.7 kg (19.2 lbs)
Top Reported Reactions
Vomiting 36
Lethargy (see also Central nervous system depression in 'Neurological') 23
Diarrhoea 16
Emesis 14
Lack of efficacy (endoparasite) - hookworm 10
INEFFECTIVE, HEARTWORM LARVAE 8
Digestive tract disorder NOS 7
Emesis (multiple) 7
Most Referenced Drugs
Milbemycin Oxime + Spinosad 35
Ivermectin + Pyrantel As Pamoate Salt 20
Afoxolaner 12
Spinosad 9
Moxidectin 8
Trilostane 6
Fluralaner Chew Tablets 5
Pyrantel Pamoate;Sarolaner 5
Outcome Breakdown
Recovered/Normal
47 (32.2%)
Outcome Unknown
47 (32.2%)
Ongoing
35 (24.0%)
Recovered with Sequela
9 (6.2%)
Died
4 (2.7%)
Euthanized
4 (2.7%)
Gender Distribution
Female 83 (52.2%)
Male 73 (45.9%)
Unknown 3 (1.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 6 | |
| 2011 | 11 | |
| 2012 | 14 | |
| 2013 | 13 | |
| 2014 | 7 | |
| 2015 | 16 | |
| 2016 | 12 | |
| 2017 | 19 | |
| 2018 | 5 | |
| 2019 | 15 | |
| 2020 | 9 | |
| 2021 | 9 | |
| 2022 | 7 | |
| 2023 | 4 | |
| 2024 | 9 | |
| 2025 | 3 | |
Terrier - Manchester Pet Health Insights
Terrier - Manchester accounts for 159 FDA adverse event reports, ranking #197 by volume among dog breeds, with 8 reports (5.0%) coded as a death outcome. Mean age at report: 6.8 years, average weight 8.7 kg (19.2 lbs).
Top reported signs: Vomiting (36), Lethargy (see also Central nervous system depression in 'Neurological') (23), Diarrhoea (16). Most-referenced drug: Milbemycin Oxime + Spinosad (35 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (20) and Afoxolaner (12).
Outcome coding on 146 status-recorded reports is dominated by Recovered/Normal (32.2%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Setter (unspecified)
161 reports · 4.3% death rate
Australian Kelpie
156 reports · 1.9% death rate
Spaniel - Springer Welsh
155 reports · 3.2% death rate
Collie - Smooth-haired
152 reports · 11.2% death rate
Dachshund - Standard Wire-haired
152 reports · 2.6% death rate
Foxhound (unspecified)
168 reports · 4.8% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Terrier - Manchester? ▼
There are 159 adverse event reports involving Terrier - Manchester in the FDA database, with 8 reports involving death (5.0% death rate). Terrier - Manchester ranks #197 by report volume.
What are the most common adverse reactions reported for Terrier - Manchester? ▼
The most commonly reported adverse reactions for Terrier - Manchester are Vomiting (36 reports), Lethargy (see also Central nervous system depression in 'Neurological') (23 reports), Diarrhoea (16 reports), Emesis (14 reports), Lack of efficacy (endoparasite) - hookworm (10 reports).
What drugs are most frequently associated with Terrier - Manchester adverse events? ▼
The drugs most frequently referenced in Terrier - Manchester adverse event reports are Milbemycin Oxime + Spinosad (35 reports), Ivermectin + Pyrantel As Pamoate Salt (20 reports), Afoxolaner (12 reports), Spinosad (9 reports), Moxidectin (8 reports).
What is the average age of Terrier - Manchester in adverse event reports? ▼
The average age of Terrier - Manchester at the time of adverse event reports is 6.8 years, with an average weight of 8.7 kg (19.2 lbs).
Does a high number of adverse event reports mean Terrier - Manchester is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - Manchester safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.