Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
155
Total Reports
5
Deaths Reported
320.0%
Death Rate
6.2 yr
Avg Age at Report
Average weight at time of report: 21.1 kg (46.5 lbs)
Top Reported Reactions
Vomiting 28
Lack of efficacy - NOS 14
Lethargy (see also Central nervous system depression in 'Neurological') 13
Digestive tract disorder NOS 11
Seizure NOS 11
Other abnormal test result NOS 10
Diarrhoea 9
INEFFECTIVE, ASCARIDS NOS 8
Lack of efficacy (endoparasite) - hookworm 7
Urinary incontinence 7
Lack of efficacy (endoparasite) - whipworm 6
Pruritus 5
Emesis 5
Emesis (multiple) 5
Ataxia 5
Most Referenced Drugs
Ivermectin + Pyrantel As Pamoate Salt 28
Afoxolaner 28
Milbemycin Oxime + Spinosad 22
Fluralaner Chew Tablets 15
Oclacitinib Maleate 9
Carprofen 4
Grapiprant 4
Fluralaner 13.64% 12-Week Chew 4
Bedinvetmab 4
Desoxycorticosterone Pivalate 3
Selamectin 3
Pyrantel Pamoate;Sarolaner 3
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 3
Prednisone 2
Imidacloprid + Moxidectin 2
Outcome Breakdown
Outcome Unknown
62 (40.0%)
Recovered/Normal
51 (32.9%)
Ongoing
34 (21.9%)
Euthanized
5 (3.2%)
Recovered with Sequela
3 (1.9%)
Gender Distribution
Female 79 (51.0%)
Male 74 (47.7%)
Unknown 2 (1.3%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 1 | |
| 2011 | 4 | |
| 2012 | 7 | |
| 2013 | 5 | |
| 2014 | 14 | |
| 2015 | 21 | |
| 2016 | 8 | |
| 2017 | 21 | |
| 2018 | 12 | |
| 2019 | 10 | |
| 2020 | 8 | |
| 2021 | 6 | |
| 2022 | 5 | |
| 2023 | 12 | |
| 2024 | 15 | |
| 2025 | 6 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #202 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.