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Breed profile · FDA CVM July 2026 extract

American Curl Shorthair adverse-event record

Adverse-event filings for American Curl Shorthair (Cat) in the FDA Center for Veterinary Medicine openFDA extract. Browse cat breeds, reactions, and outcomes below.

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#178 of 510
by report volume (all breeds)
228
FDA CVM reports on file
3.5%
death-coded share of reports
#205 of 275
by death-coded share (≥50 reports)

How the 228 reports break down

By recorded gender -- every report on file for American Curl Shorthair, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 57 42.75 28.5 14.25 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for American Curl Shorthair drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, American Curl Shorthair ranks #178 of 510 by total reports (228) and #205 of 275 by death-coded share (3.5%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#178
This breed, reports of 510
#205
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. American Curl Shorthair has 228 reports now versus 220 in that prior snapshot: 8 more (3.6%).

Report change
+8
Death-coded reports
+1
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to American Curl Shorthair changes

Total Reports

228

Above-median volume

Deaths Reported

8

of 228 reports

Death-coded share of reports

3.5%

Below-median death-coded share

Avg Age at Report

7.3 yr

5.1 kg avg weight

Breed Safety Scorecard

D (47/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate B+
3.5%

Share of reports coded as a fatality

Euthanasia rate A
1.3%

Share of reports resulting in euthanasia

Full recovery rate F
17.5%

Share of reports coded "Recovered/Normal"

5-year trend F
+350%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

American Curl Shorthair death-coded reports 3.5%
Cross-breed median

3.5% of 228 american curl shorthair reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where American Curl Shorthair's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

4% 25th percentile Higher share than 25% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. American Curl Shorthair 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 5.1 kg (11.2 lbs)

Top Reported Reactions

Application site hair loss 58
Vomiting 29
Lethargy (see also Central nervous system depression in Neurological) 18
Application site scab 16
Application site alopecia 15
Lethargy (see also Central nervous system depression in 'Neurological') 14
Not eating 14
Anorexia 12

Most Referenced Drugs

Selamectin;Sarolaner 106
Frunevetmab 48
Cefovecin 29
Selamectin 27
Maropitant Citrate 19
Gabapentin 6
Oclacitinib Maleate 5
Prednisolone 5

Outcome Breakdown

Outcome Unknown
92 (40.4%)
Ongoing
87 (38.2%)
Recovered/Normal
40 (17.5%)
Died
5 (2.2%)
Euthanized
3 (1.3%)
Recovered with Sequela
1 (0.4%)

Gender Distribution

Male 122 (53.5%)
Female 101 (44.3%)
Unknown 4 (1.8%)
Mixed 1 (0.4%)

Reports by Year

Year Reports Trend
2012 1
2015 2
2016 11
2017 3
2018 4
2019 16
2020 8
2021 12
2022 26
2023 30
2024 57
2025 54
2026 4

American Curl Shorthair: low death-coded share in the FDA CVM extract

Signature read: American Curl Shorthair's 3.5% death-coded share is in the lower third of the ≥50-report cohort (median 4.8%). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, American Curl Shorthair sits at #178 of 510 by report volume among all breeds and #18 of 55 among cat breeds, with 228 reports and 8 (3.5%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #205 of 275. Mean age at report: 7.3 years, average weight 5.1 kg (11.2 lbs).

Top reported signs: Application site hair loss (58), Vomiting (29), Lethargy (see also Central nervous system depression in Neurological) (18). Most-referenced drug: Selamectin;Sarolaner (106 reports), followed by Frunevetmab (48) and Cefovecin (29).

Outcome coding on 228 status-recorded reports is dominated by Outcome Unknown (40.4%). Annual submissions ranged 1-2,026 across 13 years on file.

Cat Breeds With a Similar Report Volume

Showing 6 of 54 cat breeds in our dataset, ranked by closest report volume.

Abyssinian cat
201 reports · 9.5% death-coded
Norwegian Forest
193 reports · 5.7% death-coded
Sphynx
184 reports · 13.6% death-coded
Manx
284 reports · 11.3% death-coded
Burmese
158 reports · 11.4% death-coded
Mixed (Cat)
298 reports · 10.7% death-coded

Nationwide breeds with similar profiles

Two openFDA-derived peer sets for American Curl Shorthair, both outside the Cat family so the neighborhoods are not species containment (the similar-volume list above stays within species).

What to do with this cat

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve American Curl Shorthair? ▼
There are 228 adverse event reports involving American Curl Shorthair in the FDA database, of which 8 were death-coded (3.5% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, American Curl Shorthair ranks #178 of 510 by report volume among all breeds PlainBreed indexes (#18 of 55 among cat breeds).
Where does American Curl Shorthair sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, American Curl Shorthair is #178 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Cat, it is #18 of 55. Among breeds with at least 50 reports, its death-coded share ranks #205 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for American Curl Shorthair? ▼
The most commonly reported adverse reactions for American Curl Shorthair are Application site hair loss (58 reports), Vomiting (29 reports), Lethargy (see also Central nervous system depression in Neurological) (18 reports), Application site scab (16 reports), Application site alopecia (15 reports).
What drugs are most frequently associated with American Curl Shorthair adverse events? ▼
The drugs most frequently referenced in American Curl Shorthair adverse event reports are Selamectin;Sarolaner (106 reports), Frunevetmab (48 reports), Cefovecin (29 reports), Selamectin (27 reports), Maropitant Citrate (19 reports).
What is the average age of American Curl Shorthair in adverse event reports? ▼
The average age of American Curl Shorthair at the time of adverse event reports is 7.3 years, with an average weight of 5.1 kg (11.2 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for American Curl Shorthair (Cat), extract as of July 2026 extract. 228 reports · 8 death-coded (3.5% of reports, not a mortality rate) · #178 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →