Total Reports
569
FDA CVM filings
Adverse-event records and label data for Sheepdog - Old English (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.
Sheepdog - Old English (Dog) has 569 FDA adverse event reports on record, with 23 deaths reported (400.0% death rate) — ranking #130 by report volume. The most frequently reported reaction is Vomiting (143 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 4.5 years.
Total Reports
569
FDA CVM filings
Deaths Reported
23
of 569 reports
Death Rate
400.0%
death-coded share
Avg Age at Report
4.5 yr
31.5 kg avg weight
400.0% of 569 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
| Year | Reports | Trend |
|---|---|---|
| 2010 | 30 | |
| 2011 | 22 | |
| 2012 | 54 | |
| 2013 | 59 | |
| 2014 | 30 | |
| 2015 | 48 | |
| 2016 | 38 | |
| 2017 | 49 | |
| 2018 | 27 | |
| 2019 | 43 | |
| 2020 | 48 | |
| 2021 | 48 | |
| 2022 | 39 | |
| 2023 | 34 | |
Across the FDA Center for Veterinary Medicine adverse event database, Sheepdog - Old English accounts for 569 submitted reports and currently ranks #130 by report volume within the dog population. Of those reports, 23 involved a death outcome — a 400.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 4.5 years, with an average recorded body weight of 31.5 kg (69.5 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.
The most frequently reported clinical signs for Sheepdog - Old English are Vomiting (143 reports), Emesis (70 reports), Diarrhoea (55 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 133 reports and is the single most-referenced drug, followed by Ivermectin + Pyrantel As Pamoate Salt (48) and Pyrantel Pamoate;Sarolaner (42). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.
Outcome coding on the 519 reports with a recorded status is dominated by Recovered/Normal (38.9% of coded outcomes). Annual submission volume ranges from 2,010 to 2,023 reports across the 14 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.
Sheepdog - Old English has a moderate volume of adverse event reports (569). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.
The 400.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.
The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 133 reports. This may indicate widespread use of the medication rather than a specific safety concern for Sheepdog - Old English.
What FDA reports are and how they are collected
Why some breeds appear in more adverse event reports
Evaluating medication risks using FDA data
Drugs that appear most in adverse event reports
The reporting process and database limitations
Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.
Sheepdog - Old English ranks #130 by total report volume. Death rate (400.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.
Read our methodology — how this data is sourced, computed, and verified.