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2026 FDA CVM data 569 reports on file official source

Sheepdog - Old English — FDA Adverse Event Profile

Adverse-event records and label data for Sheepdog - Old English (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 49 36.75 24.5 12.25 0 2016 2017 2018 2019 2020 2021 2022 2023 Reports filed Death-coded reports
Annual report volume for Sheepdog - Old English drawn from FDA CVM filings.

Sheepdog - Old English (Dog) has 569 FDA adverse event reports on record, with 23 deaths reported (400.0% death rate) — ranking #130 by report volume. The most frequently reported reaction is Vomiting (143 cases). The top associated drug is Milbemycin Oxime + Spinosad. Average age at report: 4.5 years.

Total Reports

569

FDA CVM filings

Deaths Reported

23

of 569 reports

Death Rate

400.0%

death-coded share

Avg Age at Report

4.5 yr

31.5 kg avg weight

Death-Coded Outcome Share

Sheepdog - Old English death-coded reports 100.0%
Database median

400.0% of 569 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 31.5 kg (69.5 lbs)

Top Reported Reactions

Vomiting 143
Emesis 70
Diarrhoea 55
Lethargy (see also Central nervous system depression in 'Neurological') 44
Lack of efficacy (endoparasite) - hookworm 24
Lack of efficacy - NOS 21
Lack of efficacy (ectoparasite) - tick NOS 20
Anorexia 19
Lack of efficacy (bacteria) - Borrelia 19
Lack of efficacy (endoparasite) - roundworm NOS 17
Lack of efficacy (ectoparasite) - flea 16
Seizure NOS 16
Emesis (multiple) 16
Weight loss 14
Other abnormal test result NOS 14

Most Referenced Drugs

Milbemycin Oxime + Spinosad 133
Ivermectin + Pyrantel As Pamoate Salt 48
Pyrantel Pamoate;Sarolaner 42
Spinosad 39
Afoxolaner 33
Carprofen 32
Fluralaner Chew Tablets 31
Moxidectin 29
Milbemycin Oxime + Praziquantel 28
Oclacitinib Maleate 19
Fluralaner 13.64% 12-Week Chew 16
Sarolaner 15
Lotilaner 11
Milbemycin Oxime 9
Imidacloprid + Moxidectin 9

Outcome Breakdown

Recovered/Normal
202 (38.9%)
Outcome Unknown
140 (27.0%)
Ongoing
127 (24.5%)
Recovered with Sequela
27 (5.2%)
Died
12 (2.3%)
Euthanized
11 (2.1%)

Gender Distribution

Male 313 (55.0%)
Female 253 (44.5%)
Unknown 2 (0.4%)
Mixed 1 (0.2%)

Reports by Year

Year Reports Trend
2010 30
2011 22
2012 54
2013 59
2014 30
2015 48
2016 38
2017 49
2018 27
2019 43
2020 48
2021 48
2022 39
2023 34
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Sheepdog - Old English sits in the registered size-class taxonomy. Average reported weight: 31.5 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Sheepdog - Old English Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Sheepdog - Old English accounts for 569 submitted reports and currently ranks #130 by report volume within the dog population. Of those reports, 23 involved a death outcome — a 400.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 4.5 years, with an average recorded body weight of 31.5 kg (69.5 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Sheepdog - Old English are Vomiting (143 reports), Emesis (70 reports), Diarrhoea (55 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Spinosad appears in 133 reports and is the single most-referenced drug, followed by Ivermectin + Pyrantel As Pamoate Salt (48) and Pyrantel Pamoate;Sarolaner (42). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 519 reports with a recorded status is dominated by Recovered/Normal (38.9% of coded outcomes). Annual submission volume ranges from 2,010 to 2,023 reports across the 14 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Sheepdog - Old English Adverse Event Data

Sheepdog - Old English has a moderate volume of adverse event reports (569). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 400.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Spinosad, appearing in 133 reports. This may indicate widespread use of the medication rather than a specific safety concern for Sheepdog - Old English.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Sheepdog - Old English?
There are 569 adverse event reports involving Sheepdog - Old English in the FDA database, with 23 reports involving death (400.0% death rate). Sheepdog - Old English ranks #130 by report volume.
What are the most common adverse reactions reported for Sheepdog - Old English?
The most commonly reported adverse reactions for Sheepdog - Old English are Vomiting (143 reports), Emesis (70 reports), Diarrhoea (55 reports), Lethargy (see also Central nervous system depression in 'Neurological') (44 reports), Lack of efficacy (endoparasite) - hookworm (24 reports).
What drugs are most frequently associated with Sheepdog - Old English adverse events?
The drugs most frequently referenced in Sheepdog - Old English adverse event reports are Milbemycin Oxime + Spinosad (133 reports), Ivermectin + Pyrantel As Pamoate Salt (48 reports), Pyrantel Pamoate;Sarolaner (42 reports), Spinosad (39 reports), Afoxolaner (33 reports).
What is the average age of Sheepdog - Old English in adverse event reports?
The average age of Sheepdog - Old English at the time of adverse event reports is 4.5 years, with an average weight of 31.5 kg (69.5 lbs).
Does a high number of adverse event reports mean Sheepdog - Old English is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Sheepdog - Old English safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Sheepdog - Old English ranks #130 by total report volume. Death rate (400.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial