Total Reports
569
FDA CVM filings
Dog /
FDA CVM · 2025 release 569 reports on file
Sheepdog - Old English - FDA Adverse Event Profile
Adverse-event records for Sheepdog - Old English (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 569 reports on file, Sheepdog - Old English sits at #130 among dog breeds by volume; death-coded share is 4.0% (23 reports).
- #130
- most-reported dog breed
- 4.0%
- death-coded report share
- 143
- Vomiting - top reaction
- 4.5 yr
- average age at report
Read report counts next to breed popularity: a bigger number often just means more owners and more vet visits.
Deaths Reported
23
of 569 reports
Death Rate
4.0%
death-coded share
Avg Age at Report
4.5 yr
31.5 kg avg weight
Death-Coded Outcome Share
Sheepdog - Old English death-coded reports 4.0%
Cross-breed median
4.0% of 569 sheepdog - old english reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 31.5 kg (69.5 lbs)
Top Reported Reactions
Vomiting 143
Emesis 70
Diarrhoea 55
Lethargy (see also Central nervous system depression in 'Neurological') 44
Lack of efficacy (endoparasite) - hookworm 24
Lack of efficacy - NOS 21
Lack of efficacy (ectoparasite) - tick NOS 20
Anorexia 19
Most Referenced Drugs
Milbemycin Oxime + Spinosad 133
Ivermectin + Pyrantel As Pamoate Salt 48
Pyrantel Pamoate;Sarolaner 42
Spinosad 39
Afoxolaner 33
Carprofen 32
Fluralaner Chew Tablets 31
Moxidectin 29
Outcome Breakdown
Recovered/Normal
202 (38.9%)
Outcome Unknown
140 (27.0%)
Ongoing
127 (24.5%)
Recovered with Sequela
27 (5.2%)
Died
12 (2.3%)
Euthanized
11 (2.1%)
Gender Distribution
Male 313 (55.0%)
Female 253 (44.5%)
Unknown 2 (0.4%)
Mixed 1 (0.2%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 30 | |
| 2011 | 22 | |
| 2012 | 54 | |
| 2013 | 59 | |
| 2014 | 30 | |
| 2015 | 48 | |
| 2016 | 38 | |
| 2017 | 49 | |
| 2018 | 27 | |
| 2019 | 43 | |
| 2020 | 48 | |
| 2021 | 48 | |
| 2022 | 39 | |
| 2023 | 34 | |
Sheepdog - Old English Pet Health Insights
Sheepdog - Old English accounts for 569 FDA adverse event reports, ranking #130 by volume among dog breeds, with 23 reports (4.0%) coded as a death outcome. Mean age at report: 4.5 years, average weight 31.5 kg (69.5 lbs).
Top reported signs: Vomiting (143), Emesis (70), Diarrhoea (55). Most-referenced drug: Milbemycin Oxime + Spinosad (133 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (48) and Pyrantel Pamoate;Sarolaner (42).
Outcome coding on 519 status-recorded reports is dominated by Recovered/Normal (38.9%). Annual submissions ranged 2,010-2,023 across 14 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Sheepdog - Old English? ▼
There are 569 adverse event reports involving Sheepdog - Old English in the FDA database, with 23 reports involving death (4.0% death rate). Sheepdog - Old English ranks #130 by report volume.
What are the most common adverse reactions reported for Sheepdog - Old English? ▼
The most commonly reported adverse reactions for Sheepdog - Old English are Vomiting (143 reports), Emesis (70 reports), Diarrhoea (55 reports), Lethargy (see also Central nervous system depression in 'Neurological') (44 reports), Lack of efficacy (endoparasite) - hookworm (24 reports).
What drugs are most frequently associated with Sheepdog - Old English adverse events? ▼
The drugs most frequently referenced in Sheepdog - Old English adverse event reports are Milbemycin Oxime + Spinosad (133 reports), Ivermectin + Pyrantel As Pamoate Salt (48 reports), Pyrantel Pamoate;Sarolaner (42 reports), Spinosad (39 reports), Afoxolaner (33 reports).
What is the average age of Sheepdog - Old English in adverse event reports? ▼
The average age of Sheepdog - Old English at the time of adverse event reports is 4.5 years, with an average weight of 31.5 kg (69.5 lbs).
Does a high number of adverse event reports mean Sheepdog - Old English is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Sheepdog - Old English safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.