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2026 FDA CVM data 559 reports on file official source

Cattle Dog (unspecified) — FDA Adverse Event Profile

Adverse-event records and label data for Cattle Dog (unspecified) (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

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Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 71 53.25 35.5 17.75 0 2018 2019 2020 2021 2022 2023 2024 2025 Reports filed Death-coded reports
Annual report volume for Cattle Dog (unspecified) drawn from FDA CVM filings.

Cattle Dog (unspecified) (Dog) has 559 FDA adverse event reports on record, with 27 deaths reported (480.0% death rate) — ranking #133 by report volume. The most frequently reported reaction is Vomiting (98 cases). The top associated drug is Moxidectin. Average age at report: 5.0 years.

Total Reports

559

FDA CVM filings

Deaths Reported

27

of 559 reports

Death Rate

480.0%

death-coded share

Avg Age at Report

5.0 yr

20.7 kg avg weight

Death-Coded Outcome Share

Cattle Dog (unspecified) death-coded reports 100.0%
Database median

480.0% of 559 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 20.7 kg (45.6 lbs)

Top Reported Reactions

Vomiting 98
Lack of efficacy (endoparasite) - heartworm 85
Lethargy (see also Central nervous system depression in 'Neurological') 50
Diarrhoea 39
Lack of efficacy - NOS 35
Seizure NOS 28
Emesis 22
Lack of efficacy (ectoparasite) - flea 18
Panting 18
Lack of efficacy (endoparasite) - hookworm 18
Behavioural disorder NOS 16
Elevated alanine aminotransferase (ALT) 16
Lethargy (see also Central nervous system depression in Neurological) 16
Decreased appetite 15
Death 15

Most Referenced Drugs

Moxidectin 107
Milbemycin Oxime + Spinosad 90
Pyrantel Pamoate;Sarolaner 82
Milbemycin Oxime + Praziquantel 47
Oclacitinib Maleate 43
Bedinvetmab 31
Sarolaner 29
Melarsomine Dihydrochloride 27
Carprofen 24
Maropitant Citrate 22
Selamectin 16
Lotilaner 15
Gabapentin 14
Spinosad 13
Dexmedetomidine Hydrochloride 13

Outcome Breakdown

Ongoing
264 (47.2%)
Recovered/Normal
143 (25.6%)
Outcome Unknown
116 (20.8%)
Died
18 (3.2%)
Recovered with Sequela
9 (1.6%)
Euthanized
9 (1.6%)

Gender Distribution

Female 310 (55.5%)
Male 240 (42.9%)
Unknown 7 (1.3%)
Mixed 2 (0.4%)

Reports by Year

Year Reports Trend
2012 15
2013 33
2014 30
2015 17
2016 34
2017 43
2018 40
2019 36
2020 59
2021 71
2022 43
2023 50
2024 62
2025 26
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Cattle Dog (unspecified) sits in the registered size-class taxonomy. Average reported weight: 20.7 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Cattle Dog (unspecified) Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Cattle Dog (unspecified) accounts for 559 submitted reports and currently ranks #133 by report volume within the dog population. Of those reports, 27 involved a death outcome — a 480.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 5.0 years, with an average recorded body weight of 20.7 kg (45.6 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Cattle Dog (unspecified) are Vomiting (98 reports), Lack of efficacy (endoparasite) - heartworm (85 reports), Lethargy (see also Central nervous system depression in 'Neurological') (50 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Moxidectin appears in 107 reports and is the single most-referenced drug, followed by Milbemycin Oxime + Spinosad (90) and Pyrantel Pamoate;Sarolaner (82). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 559 reports with a recorded status is dominated by Ongoing (47.2% of coded outcomes). Annual submission volume ranges from 2,012 to 2,025 reports across the 14 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Cattle Dog (unspecified) Adverse Event Data

Cattle Dog (unspecified) has a moderate volume of adverse event reports (559). Report counts are influenced by breed popularity, owner awareness, and veterinary reporting practices.

The 480.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.

The most frequently referenced drug in adverse reports is Moxidectin, appearing in 107 reports. This may indicate widespread use of the medication rather than a specific safety concern for Cattle Dog (unspecified).

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Cattle Dog (unspecified)?
There are 559 adverse event reports involving Cattle Dog (unspecified) in the FDA database, with 27 reports involving death (480.0% death rate). Cattle Dog (unspecified) ranks #133 by report volume.
What are the most common adverse reactions reported for Cattle Dog (unspecified)?
The most commonly reported adverse reactions for Cattle Dog (unspecified) are Vomiting (98 reports), Lack of efficacy (endoparasite) - heartworm (85 reports), Lethargy (see also Central nervous system depression in 'Neurological') (50 reports), Diarrhoea (39 reports), Lack of efficacy - NOS (35 reports).
What drugs are most frequently associated with Cattle Dog (unspecified) adverse events?
The drugs most frequently referenced in Cattle Dog (unspecified) adverse event reports are Moxidectin (107 reports), Milbemycin Oxime + Spinosad (90 reports), Pyrantel Pamoate;Sarolaner (82 reports), Milbemycin Oxime + Praziquantel (47 reports), Oclacitinib Maleate (43 reports).
What is the average age of Cattle Dog (unspecified) in adverse event reports?
The average age of Cattle Dog (unspecified) at the time of adverse event reports is 5.0 years, with an average weight of 20.7 kg (45.6 lbs).
Does a high number of adverse event reports mean Cattle Dog (unspecified) is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Cattle Dog (unspecified) safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Cattle Dog (unspecified) ranks #133 by total report volume. Death rate (480.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial