Total Reports
529
FDA CVM filings
Dog /
FDA CVM · 2025 release 529 reports on file
Bullmastiff - FDA Adverse Event Profile
Adverse-event records for Bullmastiff (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 529 reports on file, Bullmastiff sits at #136 among dog breeds by volume; death-coded share is 6.2% (33 reports).
- #136
- most-reported dog breed
- 6.2%
- death-coded report share
- 103
- Vomiting - top reaction
- 3.8 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
33
of 529 reports
Death Rate
6.2%
death-coded share
Avg Age at Report
3.8 yr
46.4 kg avg weight
Death-Coded Outcome Share
Bullmastiff death-coded reports 6.2%
Cross-breed median
6.2% of 529 bullmastiff reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 46.4 kg (102.3 lbs)
Top Reported Reactions
Vomiting 103
Emesis 58
Lethargy (see also Central nervous system depression in 'Neurological') 47
Diarrhoea 43
Lack of efficacy (endoparasite) - heartworm 33
INEFFECTIVE, HEARTWORM LARVAE 31
Anorexia 26
Lack of efficacy (ectoparasite) - flea 25
Most Referenced Drugs
Milbemycin Oxime + Spinosad 141
Ivermectin + Pyrantel As Pamoate Salt 83
Spinosad 39
Milbemycin Oxime + Praziquantel 35
Carprofen 34
Afoxolaner 23
Oclacitinib Maleate 22
Fluralaner Chew Tablets 21
Outcome Breakdown
Recovered/Normal
170 (34.6%)
Outcome Unknown
169 (34.4%)
Ongoing
101 (20.6%)
Euthanized
19 (3.9%)
Recovered with Sequela
18 (3.7%)
Died
14 (2.9%)
Gender Distribution
Male 283 (53.5%)
Female 226 (42.7%)
Unknown 17 (3.2%)
Mixed 3 (0.6%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 14 | |
| 2011 | 32 | |
| 2012 | 40 | |
| 2013 | 34 | |
| 2014 | 49 | |
| 2015 | 48 | |
| 2016 | 49 | |
| 2017 | 48 | |
| 2018 | 42 | |
| 2019 | 31 | |
| 2020 | 29 | |
| 2021 | 25 | |
| 2022 | 25 | |
| 2023 | 16 | |
| 2024 | 31 | |
| 2025 | 16 | |
Bullmastiff Pet Health Insights
Bullmastiff accounts for 529 FDA adverse event reports, ranking #136 by volume among dog breeds, with 33 reports (6.2%) coded as a death outcome. Mean age at report: 3.8 years, average weight 46.4 kg (102.3 lbs).
Top reported signs: Vomiting (103), Emesis (58), Lethargy (see also Central nervous system depression in 'Neurological') (47). Most-referenced drug: Milbemycin Oxime + Spinosad (141 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (83) and Spinosad (39).
Outcome coding on 491 status-recorded reports is dominated by Recovered/Normal (34.6%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Bullmastiff? ▼
There are 529 adverse event reports involving Bullmastiff in the FDA database, with 33 reports involving death (6.2% death rate). Bullmastiff ranks #136 by report volume.
What are the most common adverse reactions reported for Bullmastiff? ▼
The most commonly reported adverse reactions for Bullmastiff are Vomiting (103 reports), Emesis (58 reports), Lethargy (see also Central nervous system depression in 'Neurological') (47 reports), Diarrhoea (43 reports), Lack of efficacy (endoparasite) - heartworm (33 reports).
What drugs are most frequently associated with Bullmastiff adverse events? ▼
The drugs most frequently referenced in Bullmastiff adverse event reports are Milbemycin Oxime + Spinosad (141 reports), Ivermectin + Pyrantel As Pamoate Salt (83 reports), Spinosad (39 reports), Milbemycin Oxime + Praziquantel (35 reports), Carprofen (34 reports).
What is the average age of Bullmastiff in adverse event reports? ▼
The average age of Bullmastiff at the time of adverse event reports is 3.8 years, with an average weight of 46.4 kg (102.3 lbs).
Does a high number of adverse event reports mean Bullmastiff is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Bullmastiff safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.